1.
Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiti..
[3094]
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2.
Enhanced base editing by co-expression of free uracil DNA glycosyl..
[2863]
|
3.
A pan-coronavirus fusion inhibitor targeting the HR1 domain of hum..
[1774]
|
4.
Comparison of cytosine base editors and development of the BEable-..
[1238]
|
5.
Selection of an ASIC1a-blocking combinatorial antibody that protec..
[1181]
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6.
Base editing with a Cpf1-cytidine deaminase fusion
[1150]
|
7.
Highly efficient prime editing by introducing same-sense mutations..
[1145]
|
8.
Eliminating base-editor-induced genome-wide and transcriptome-wide..
[916]
|
9.
Efficient base editing in methylated regions with a human APOBEC3A..
[884]
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10.
Identification of recombinant Fabs for structural and functional c..
[841]
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11.
Cas12a Base Editors Induce Efficient and Specific Editing with Low..
[827]
|
12.
Inhibitory antibodies identify unique sites of therapeutic vulnera..
[808]
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13.
Structures and immune recognition of Env trimers from two Asia pre..
[754]
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14.
Selection of a picomolar antibody that targets CXCR2-mediated neut..
[744]
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15.
To BE or not to BE, that is the question
[736]
|
16.
APOBEC3 induces mutations during repair of CRISPR-Cas9-generated D..
[732]
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17.
One Prime for All Editing
[657]
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18.
Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived pept..
[647]
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19.
Crl activates transcription by stabilizing active conformation of ..
[634]
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20.
Development and Application of Base Editors
[614]
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21.
Antigenic mapping reveals sites of vulnerability on alpha-HCoV spi..
[611]
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22.
Crystal structure of the post-fusion core of the Human coronavirus..
[573]
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23.
Discrete RNA–DNA hybrid cleavage by the EXD2 exonuclease pinpoint..
[552]
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24.
APOBEC: From mutator to editor
[551]
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25.
一种包含支架的引导RNA及利用其的遗传编辑的方法
[531]
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26.
GENOMIC EDITING OF IMPROVED EFFICIENCY AND ACCURACY
[483]
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27.
BASE EDITING SYSTEM AND METHOD
[476]
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28.
Base editing of the HBG promoter induces potent fetal hemoglobin e..
[408]
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29.
一种融合蛋白在遗传编辑的用途
[405]
|
30.
一对用于编辑人PCSK9核酸序列的辅助引导RNA//引导RNA
[396]
|
31.
FUSION PROTEINS FOR BASE EDITING
[393]
|
32.
一种碱基编辑分子及其用途
[386]
|
33.
抑制基因编辑中的非预期突变
[382]
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34.
一种基因碱基编辑器
[376]
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35.
一种碱基编辑分子及其用途
[369]
|
36.
用于碱基编辑的融合蛋白
[368]
|
37.
Inhibition of unintended mutations in gene editing
[366]
|
38.
FUSION PROTEINS FOR IMPROVED PRECISION IN BASE EDITING
[362]
|
39.
用于治疗β-血红蛋白病的基因疗法
[362]
|
40.
GENE THERAPY FOR TREATING BETA-HEMOGLOBINOPATHIES
[356]
|
41.
Visualization of conformational transition of GRP94 in solution
[354]
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42.
提高效率和准确性的基因组编辑
[353]
|
43.
基因编辑中非故意突变的抑制
[352]
|
44.
用于治疗β-血红蛋白病的基因疗法
[352]
|
45.
Amplification editing enables efficient and precise duplication of..
[350]
|
46.
一对用于编辑人PCSK9核酸序列的辅助引导RNA//引导RNA
[349]
|
47.
提高效率和准确性的基因组编辑
[349]
|
48.
提高效率和准确性的基因组编辑
[344]
|
49.
提高效率和准确性的基因组编辑
[337]
|
50.
基因编辑中非预期突变的抑制
[336]
|
51.
FUSION PROTEINS FOR IMPROVED PRECISION IN BASE EDITING
[333]
|
52.
促进人细胞中γ-珠蛋白产生的方法,编码CRISPR相关蛋白(CAS)、核碱基脱..
[325]
|
53.
Recent progress in gene therapy for familial hypercholesterolemia ..
[316]
|
54.
提高效率和准确性的基因组编辑
[312]
|
55.
用于碱基编辑的融合蛋白
[311]
|
56.
用于提高碱基编辑精度的融合蛋白
[310]
|
57.
用于治疗β-血红蛋白病的基因疗法
[309]
|
58.
基因疗法治疗β-血红蛋白病
[297]
|
59.
基因编辑中非预期突变的抑制
[295]
|
60.
提高效率和准确性的基因组编辑
[292]
|
61.
用于治疗β-血红蛋白病的基因疗法
[291]
|
62.
用于提高碱基编辑精度的融合蛋白
[289]
|
63.
基因编辑中非有意突变的抑制
[288]
|
64.
一种基因碱基编辑器
[286]
|
65.
抑制基因编辑中的非预期突变
[279]
|
66.
FUSION PROTEINS FOR IMPROVED PRECISION IN BASE EDITING
[278]
|
67.
INHIBITION OF UNINTENDED MUTATIONS IN GENE EDITING
[276]
|
68.
FUSION PROTEINS FOR BASE EDITING
[263]
|
69.
基因编辑中非故意突变的抑制
[263]
|
70.
一种碱基编辑系统及其构建和应用方法
[260]
|
71.
用于治疗β-血红蛋白病的基因疗法
[256]
|
72.
基因编辑中非故意突变的抑制
[253]
|
73.
用于治疗β-血红蛋白病的基因疗法
[251]
|
74.
用于提高碱基编辑精度的融合蛋白
[249]
|
75.
Prime editor-mediated functional reshaping of ACE2 prevents the en..
[248]
|
76.
基因编辑中非预期突变的抑制
[235]
|
77.
基因编辑中非故意突变的抑制
[235]
|
78.
FUSION PROTEINS FOR BASE EDITING
[232]
|
79.
用于碱基编辑的融合蛋白
[226]
|
80.
基因编辑中非故意突变的抑制
[212]
|
81.
基因编辑中非故意突变的抑制
[204]
|
82.
CRISP相关蛋白(CAS)、核baze脱氨基、单指导RNA(SGRNA)和帮助单指导RNA(..
[95]
|
83.
Specific and efficient RNA A-to-I editing through cleavage of an A..
[77]
|
84.
高效和特异性的RNA编辑系统
[42]
|
85.
Leveraging base excision repair for efficient adenine base editing..
[30]
|