1.
Enhanced base editing by co-expression of free uracil DNA glycosyl..
[2862]
|
2.
Efficient generation of mouse models of human diseases via ABE- an..
[1568]
|
3.
Efficient base editing in G/C-rich regions to model androgen insen..
[1373]
|
4.
BE-PLUS: a new base editing tool with broadened editing window and..
[1263]
|
5.
Highly efficient and precise base editing in discarded human tripr..
[1247]
|
6.
Comparison of cytosine base editors and development of the BEable-..
[1238]
|
7.
Base editing with a Cpf1-cytidine deaminase fusion
[1148]
|
8.
Loss of Sun2 promotes the progression of prostate cancer by regula..
[1146]
|
9.
Highly efficient prime editing by introducing same-sense mutations..
[1141]
|
10.
Eliminating base-editor-induced genome-wide and transcriptome-wide..
[914]
|
11.
Efficient base editing in methylated regions with a human APOBEC3A..
[881]
|
12.
Cas12a Base Editors Induce Efficient and Specific Editing with Low..
[825]
|
13.
To BE or not to BE, that is the question
[736]
|
14.
Breaking bad: The mutagenic effect of DNA repair
[732]
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15.
APOBEC3 induces mutations during repair of CRISPR-Cas9-generated D..
[732]
|
16.
Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base..
[670]
|
17.
Knockout of circRNAs by base editing back-splice sites of circular..
[660]
|
18.
One Prime for All Editing
[657]
|
19.
Generation of isogenic single and multiplex gene knockout mice by ..
[636]
|
20.
Development and Application of Base Editors
[611]
|
21.
Gene editing and its applications in biomedicine
[584]
|
22.
The Future of Genome Editing
[559]
|
23.
Discrete RNA–DNA hybrid cleavage by the EXD2 exonuclease pinpoint..
[551]
|
24.
APOBEC: From mutator to editor
[549]
|
25.
一种包含支架的引导RNA及利用其的遗传编辑的方法
[531]
|
26.
GENOMIC EDITING OF IMPROVED EFFICIENCY AND ACCURACY
[481]
|
27.
BASE EDITING SYSTEM AND METHOD
[475]
|
28.
Genomic and Transcriptomic Analyses of Prime Editing Guide RNA-Ind..
[460]
|
29.
Base editing of the HBG promoter induces potent fetal hemoglobin e..
[407]
|
30.
一种融合蛋白在遗传编辑的用途
[403]
|
31.
一对用于编辑人PCSK9核酸序列的辅助引导RNA//引导RNA
[396]
|
32.
FUSION PROTEINS FOR BASE EDITING
[392]
|
33.
一种碱基编辑分子及其用途
[386]
|
34.
Design and application of the transformer base editor in mammalian..
[383]
|
35.
抑制基因编辑中的非预期突变
[382]
|
36.
CRISPR Adventures in China
[376]
|
37.
一种基因碱基编辑器
[376]
|
38.
用于碱基编辑的融合蛋白
[367]
|
39.
一种碱基编辑分子及其用途
[366]
|
40.
Inhibition of unintended mutations in gene editing
[366]
|
41.
用于治疗β-血红蛋白病的基因疗法
[362]
|
42.
GENE THERAPY FOR TREATING BETA-HEMOGLOBINOPATHIES
[355]
|
43.
用于治疗β-血红蛋白病的基因疗法
[352]
|
44.
提高效率和准确性的基因组编辑
[352]
|
45.
一对用于编辑人PCSK9核酸序列的辅助引导RNA//引导RNA
[347]
|
46.
提高效率和准确性的基因组编辑
[346]
|
47.
提高效率和准确性的基因组编辑
[343]
|
48.
No observable guide-RNA-independent off-target mutation induced by..
[339]
|
49.
基因编辑中非预期突变的抑制
[336]
|
50.
提高效率和准确性的基因组编辑
[333]
|
51.
FUSION PROTEINS FOR IMPROVED PRECISION IN BASE EDITING
[332]
|
52.
促进人细胞中γ-珠蛋白产生的方法,编码CRISPR相关蛋白(CAS)、核碱基脱..
[323]
|
53.
提高效率和准确性的基因组编辑
[312]
|
54.
A Tale of Two Moieties: Rapidly Evolving CRISPR/Cas-Based Genome E..
[310]
|
55.
用于碱基编辑的融合蛋白
[308]
|
56.
用于提高碱基编辑精度的融合蛋白
[308]
|
57.
用于治疗β-血红蛋白病的基因疗法
[308]
|
58.
Base editing of organellar DNA with programmable deaminases
[298]
|
59.
基因疗法治疗β-血红蛋白病
[296]
|
60.
基因编辑中非预期突变的抑制
[294]
|
61.
提高效率和准确性的基因组编辑
[291]
|
62.
用于治疗β-血红蛋白病的基因疗法
[290]
|
63.
用于提高碱基编辑精度的融合蛋白
[288]
|
64.
基因编辑中非有意突变的抑制
[285]
|
65.
一种基因碱基编辑器
[284]
|
66.
抑制基因编辑中的非预期突变
[279]
|
67.
FUSION PROTEINS FOR IMPROVED PRECISION IN BASE EDITING
[277]
|
68.
INHIBITION OF UNINTENDED MUTATIONS IN GENE EDITING
[276]
|
69.
一种纳米抗菌材料及其制备方法
[272]
|
70.
FUSION PROTEINS FOR BASE EDITING
[263]
|
71.
基因编辑中非故意突变的抑制
[262]
|
72.
一种碱基编辑系统及其构建和应用方法
[259]
|
73.
硅纳米针阵列抗菌材料的制备及其抗菌性能研究
[252]
|
74.
基因编辑中非故意突变的抑制
[251]
|
75.
用于治疗β-血红蛋白病的基因疗法
[249]
|
76.
计算生物学分析在基因组编辑研究中的应用
[246]
|
77.
用于提高碱基编辑精度的融合蛋白
[246]
|
78.
Prime editor-mediated functional reshaping of ACE2 prevents the en..
[246]
|
79.
基因编辑中非故意突变的抑制
[245]
|
80.
基因编辑中非预期突变的抑制
[234]
|
81.
基因编辑中非故意突变的抑制
[232]
|
82.
Marketing's Role in Promoting the Common Good: A Systematic Examin..
[230]
|
83.
FUSION PROTEINS FOR BASE EDITING
[229]
|
84.
用于碱基编辑的融合蛋白
[224]
|
85.
碱基编辑技术的发展与应用
[213]
|
86.
基因编辑中非故意突变的抑制
[211]
|
87.
Expanding genome editing scopes with artificial intelligence
[154]
|
88.
Targeted Delivery of mRNA with Polymer-Lipid Nanoparticles for In ..
[126]
|
89.
Efficient Genome Editing of Human T Cells with Innovative Transfor..
[120]
|
90.
Innovative Transformer Base Editor (tBE)-Mediated Undetected Off-T..
[119]
|
91.
Development of Best-in-Class Gene Editing Therapy for β-Hemoglo..
[116]
|
92.
Precise Base Editing of Hyperlipidemia-Associated Genes by the Tra..
[104]
|
93.
CRISP相关蛋白(CAS)、核baze脱氨基、单指导RNA(SGRNA)和帮助单指导RNA(..
[95]
|
94.
Specific and efficient RNA A-to-I editing through cleavage of an A..
[73]
|
95.
高效和特异性的RNA编辑系统
[41]
|
96.
Rapid, Efficient and Durable Fetal Hemoglobin Production Following..
[31]
|
97.
Leveraging base excision repair for efficient adenine base editing..
[29]
|