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合作作者[TOP 5]

  • 杨海涛

    合作成果数：75

  • 杨秀娜

    合作成果数：68

  • 赵耀

    合作成果数：32

  • Guddat, Luke W.

    合作成果数：32

  • 高岩

    合作成果数：20

访问统计


  总访问量
 2300
  访问来源
    内部： 12
    外部： 2288
    国内： 1979
    国外： 321

  年访问量
 202
  访问来源
    内部： 0
    外部： 202
    国内： 178
    国外： 24

  月访问量
 37
  访问来源
    内部： 0
    外部： 37
    国内： 31
    国外： 6

访问量

访问量

1. Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors [6503]
2. Structure of the RNA-dependent RNA polymerase from COVID-19 virus [3225]
3. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase [1786]
4. Structure-based design of antiviral drug candidates targeting the .. [1509]
5. Structure of the herpes simplex virus type 2 C-capsid with capsid-.. [1346]
6. Structures of cell wall arabinosyltransferases with the anti-tuber.. [1320]
7. Structural basis of trehalose recycling by the ABC transporter Lpq.. [1307]
8. Cryo-EM structures of a prokaryotic heme transporter CydDC [1246]
9. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxyge.. [1183]
10. Inhibition mechanism of SARS-CoV-2 main protease by ebselen and it.. [1131]
11. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug .. [1128]
12. Mycobacterial dynamin-like protein IniA mediates membrane fission [1089]
13. Structural insights into substrate recognition by the type VII sec.. [1065]
14. Structures of fungal and plant acetohydroxyacid synthases [1020]
15. Structural basis for SARS-CoV-2 neutralizing antibodies with novel.. [983]
16. Conformational Changes in a Macrolide Antibiotic Binding Protein F.. [943]
17. Discovery and characterization of potent pan-variant SARS-CoV-2 ne.. [917]
18. An electron transfer path connects subunits of a mycobacterial res.. [872]
19. Structural biology of SARS-CoV-2 and implications for therapeutic .. [863]
20. Architecture of a SARS-CoV-2 mini replication and transcription co.. [856]
21. Structure of Mycobacterium tuberculosis cytochrome bcc in complex .. [853]
22. High-throughput screening identifies established drugs as SARS-CoV.. [837]
23. Structure-based discovery of dual pathway inhibitors for SARS-CoV-.. [809]
24. Structural basis for replicase polyprotein cleavage and substrate .. [797]
25. 一种治疗和//或预防冠状病毒引发的疾病的化合物及其应用 [766]
26. High-throughput screening of SARS-CoV-2 main and papain-like prote.. [765]
27. Structural basis for the inhibition of SARS-CoV-2 main protease by.. [764]
28. Cryo-EM snapshots of mycobacterial arabinosyltransferase complex E.. [743]
29. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD.. [739]
30. Cryo-EM structure of a herpesvirus capsid at 3.1 angstrom [732]
31. Crystal structure of a membrane-bound O-acyltransferase [729]
32. Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mp.. [727]
33. 丹参提取物和醌类化合物在抗冠状病毒中的应用 [703]
34. Crystal structure of SARS-CoV-2 main protease in complex with prot.. [679]
35. The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Doma.. [671]
36. Structure basis for allosteric regulation of lymphocytic choriomen.. [671]
37. Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded .. [664]
38. Coupling of N7-methyltransferase and 3 '-5 ' exoribonuclease with .. [663]
39. 二氢杨梅素在抗冠状病毒中的应用 [646]
40. Delicate structural coordination of the Severe Acute Respiratory S.. [632]
41. Host-mediated ubiquitination of a mycobacterial protein suppresses.. [597]
42. 紫草素在抗冠状病毒中的应用 [594]
43. 柯里拉京在抗冠状病毒中的应用 [589]
44. 一种抗新冠纳米抗体及其应用 [588]
45. COMPOUND FOR TREATING AND//OR PREVENTING DISEASES CAUSED BY CORONA.. [569]
46. Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transc.. [567]
47. Crystal structure of L-glutamate N-acetyltransferase ArgA from Myc.. [563]
48. Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir [560]
49. TMPRSS2 and glycan receptors synergistically facilitate coronaviru.. [559]
50. 丙基-2-咪唑二硫醚在抗冠状病毒中的应用 [531]
51. MmpL3抑制剂、组合物及其用途 [516]
52. A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucle.. [512]
53. 苏木的活性成分在抗冠状病毒中的应用 [510]
54. APPLICATION OF DISULFIRAM IN CORONAVIRUS RESISTANCE [497]
55. 化合物在抗冠状病毒中的应用 [494]
56. Structure-based design of anti-mycobacterial drug leads that targe.. [489]
57. 一种抗新冠纳米抗体及其应用 [487]
58. Use of an N-substituted pyridyl benzisoselazolone compound [478]
59. 卡莫氟或其药学上可接受的盐在抗冠状病毒中的应用 [470]
60. Architecture of African swine fever virus and implications for vir.. [468]
61. 秦皮素在抗冠状病毒中的应用 [468]
62. 双硫仑在抗冠状病毒中的应用 [466]
63. 化合物及其用于治疗和//或预防由冠状病毒引起的疾病的用途 [465]
64. 用于治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [454]
65. 用于治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [453]
66. 一种化合物及其在制备治疗肠道病毒相关疾病的药物中的应用 [448]
67. 一种包括Nafamostat和K777的药物组合及其应用 [447]
68. 甲异靛在抗冠状病毒中的应用 [445]
69. 替徳格塞在抗冠状病毒中的应用 [437]
70. 双硫仑在冠状病毒耐药中的应用 [430]
71. 多酚类物质在抗冠状病毒中的应用 [416]
72. N-取代吡啶基苯并异硒唑酮化合物的应用 [411]
73. N-取代的吡啶基苯并异萘唑酮化合物的用途 [410]
74. 质子泵抑制剂在抗冠状病毒中的应用 [394]
75. ANTI-CORONAVIRUS APPLICATION OF COMPOUND [392]
76. De novo design of SARS-CoV-2 main protease inhibitor.. [391]
77. Aloxistatin在制备抗病毒感染的药物中的应用 [389]
78. Structure of the human ATP synthase [382]
79. 治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [382]
80. APPLICATION OF N-SUBSTITUTED PYRIDYL BENZISOSELENAZOLONE COMPOUND [379]
81. Structural insights into trehalose capture and translocation by my.. [378]
82. 一种化合物及其在制备治疗肠道病毒相关疾病的药物中的应用 [364]
83. Molecular recognition of trehalose and trehalose analogues by M.. [359]
84. Structural and functional studies of drug targets for Mycobacteriu.. [357]
85. APPLICATION OF SULFIRAM IN CORONAVIRUS RESISTANCE [355]
86. 双硫仑在抗冠状病毒中的应用 [348]
87. Inhibition of M. tuberculosis and human ATP synthase by BDQ.. [347]
88. Structure-based design of pan-coronavirus inhibitors targeting hos.. [338]
89. An oligopeptide permease, OppABCD, requires an iron-sulfur cluster.. [337]
90. Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase e.. [336]
91. A brain-to-gut signal controls intestinal fat absorption [336]
92. Molecular basis for substrate transport of Mycobacterium tuberculo.. [327]
93. MMPL3抑制剂，其组合物及其用途 [319]
94. Uses of N-substituted pyridylbenzisocellazolone compounds [318]
95. Structural analysis of phosphoribosyltransferase-mediated cell wal.. [308]
96. Uses of disulfiram in anti-coronaviruses [284]
97. Molecular recognition of trehalose and trehalose analogues by Myco.. [276]
98. Structure of the priming arabinosyltransferase AftA required for A.. [274]
99. Structural basis for the broad substrate specificity of two acyl-C.. [273]
100. 多酚类物质在抗冠状病毒中的应用 [272]

下载量

1. Structure of the RNA-dependent RNA polymerase from COVID-19 virus [620]
2. Discovery and characterization of potent pan-variant SARS-CoV-2 ne.. [428]
3. Structures of fungal and plant acetohydroxyacid synthases [410]
4. Structure of the herpes simplex virus type 2 C-capsid with capsid-.. [407]
5. Mycobacterial dynamin-like protein IniA mediates membrane fission [331]
6. Structural insights into substrate recognition by the type VII sec.. [326]
7. Architecture of a SARS-CoV-2 mini replication and transcription co.. [321]
8. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxyge.. [314]
9. Structural biology of SARS-CoV-2 and implications for therapeutic .. [293]
10. Inhibition mechanism of SARS-CoV-2 main protease by ebselen and it.. [277]
11. Conformational Changes in a Macrolide Antibiotic Binding Protein F.. [266]
12. Structural basis for SARS-CoV-2 neutralizing antibodies with novel.. [263]
13. Cryo-EM structures of a prokaryotic heme transporter CydDC [250]
14. Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mp.. [191]
15. Structure-based discovery of dual pathway inhibitors for SARS-CoV-.. [188]
16. Structure basis for allosteric regulation of lymphocytic choriomen.. [176]
17. High-throughput screening of SARS-CoV-2 main and papain-like prote.. [150]
18. The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Doma.. [80]
19. Structures of cell wall arabinosyltransferases with the anti-tuber.. [37]
20. Architecture of African swine fever virus and implications for vir.. [32]
21. Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors [29]
22. TMPRSS2 and glycan receptors synergistically facilitate coronaviru.. [27]
23. Structural basis of trehalose recycling by the ABC transporter Lpq.. [25]
24. Structure-based design of antiviral drug candidates targeting the .. [23]
25. Structure-based design of pan-coronavirus inhibitors targeting hos.. [18]
26. Host-mediated ubiquitination of a mycobacterial protein suppresses.. [12]
27. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug .. [11]
28. Cryo-EM snapshots of mycobacterial arabinosyltransferase complex E.. [11]
29. Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir [11]
30. An oligopeptide permease, OppABCD, requires an iron-sulfur cluster.. [11]
31. Structural basis for the inhibition of SARS-CoV-2 main protease by.. [10]
32. Cryo-EM structures of a mycobacterial ABC transporter that mediate.. [10]
33. Delicate structural coordination of the Severe Acute Respiratory S.. [9]
34. An electron transfer path connects subunits of a mycobacterial res.. [8]
35. Structural basis for replicase polyprotein cleavage and substrate .. [8]
36. Structure of the priming arabinosyltransferase AftA required for A.. [8]
37. Aloxistatin在制备抗病毒感染的药物中的应用 [8]
38. Inherent symmetry and flexibility in hepatitis B virus subviral pa.. [7]
39. Expanding the utilization of binding pockets proves to be effectiv.. [7]
40. 一种抗新冠纳米抗体及其应用 [6]
41. De novo design of SARS-CoV-2 main protease inhibitor.. [6]
42. Crystal structure of a membrane-bound O-acyltransferase [5]
43. COMPOUND FOR TREATING AND//OR PREVENTING DISEASES CAUSED BY CORONA.. [5]
44. Molecular basis for substrate transport of Mycobacterium tuberculo.. [5]
45. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase [4]
46. MmpL3抑制剂、组合物及其用途 [4]
47. Use of an N-substituted pyridyl benzisoselazolone compound [4]
48. Structure-based design of anti-mycobacterial drug leads that targe.. [4]
49. Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded .. [4]
50. 一种包括Nafamostat和K777的药物组合及其应用 [4]
51. APPLICATION OF N-SUBSTITUTED PYRIDYL BENZISOSELENAZOLONE COMPOUND [3]
52. 丹参提取物和醌类化合物在抗冠状病毒中的应用 [3]
53. 双硫仑在抗冠状病毒中的应用 [3]
54. Uses of N-substituted pyridylbenzisocellazolone compounds [3]
55. 紫草素在抗冠状病毒中的应用 [3]
56. 双硫仑在冠状病毒耐药中的应用 [3]
57. 用于治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [3]
58. N-取代吡啶基苯并异硒唑酮类化合物的应用 [3]
59. Structural analysis of phosphoribosyltransferase-mediated cell wal.. [3]
60. The structural and functional analysis of mycobacteria cysteine de.. [3]
61. Crystal structure of L-glutamate N-acetyltransferase ArgA from Myc.. [2]
62. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD.. [2]
63. High-throughput screening identifies established drugs as SARS-CoV.. [2]
64. Coupling of N7-methyltransferase and 3 '-5 ' exoribonuclease with .. [2]
65. Crystal structure of SARS-CoV-2 main protease in complex with prot.. [2]
66. Structure of Mycobacterium tuberculosis cytochrome bcc in complex .. [2]
67. MMPL3 INHIBITORS, COMPOSITIONS AND USES THEREOF [2]
68. N-取代吡啶基苯并异硒唑酮化合物的应用 [2]
69. 质子泵抑制剂在抗冠状病毒中的应用 [2]
70. Uses of disulfiram in anti-coronaviruses [2]
71. 苏木的活性成分在抗冠状病毒中的应用 [2]
72. APPLICATION OF DISULFIRAM IN CORONAVIRUS RESISTANCE [2]
73. 一种治疗和//或预防冠状病毒引发的疾病的化合物及其应用 [2]
74. 二氢杨梅素在抗冠状病毒中的应用 [2]
75. 用于治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [2]
76. 多酚类物质在抗冠状病毒中的应用 [2]
77. 双硫仑在抗冠状病毒中的应用 [2]
78. 双硫仑在抗冠状病毒中的应用 [2]
79. N-取代的吡啶基苯并异萘唑酮化合物的用途 [2]
80. 治疗和//或预防由冠状病毒引起的疾病的化合物及其用途 [2]
81. 一种抗新冠纳米抗体及其应用 [2]
82. 化合物在抗冠状病毒中的应用 [2]
83. 一种化合物及其在制备治疗肠道病毒相关疾病的药物中的应用 [2]
84. A brain-to-gut signal controls intestinal fat absorption [2]
85. 一种化合物及其在制备治疗肠道病毒相关疾病的药物中的应用 [2]
86. Cryo-EM structure of a herpesvirus capsid at 3.1 angstrom [1]
87. ANTI-CORONAVIRUS APPLICATION OF COMPOUND [1]
88. 多酚类物质在抗冠状病毒中的应用 [1]
89. 甲异靛在抗冠状病毒中的应用 [1]
90. 替徳格塞在抗冠状病毒中的应用 [1]
91. A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucle.. [1]
92. 丙基-2-咪唑二硫醚在抗冠状病毒中的应用 [1]
93. 柯里拉京在抗冠状病毒中的应用 [1]
94. 秦皮素在抗冠状病毒中的应用 [1]
95. 卡莫氟或其药学上可接受的盐在抗冠状病毒中的应用 [1]
96. Structural insights into trehalose capture and translocation by my.. [1]
97. Inhibition of M. tuberculosis and human ATP synthase by BDQ.. [1]