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合作作者[TOP 5]

  • 赵素文

    合作成果数：51

  • 刘志杰

    合作成果数：20

  • Raymond C. Stevens

    合作成果数：20

  • 徐菲

    合作成果数：16

  • 武丽杰

    合作成果数：15

访问统计


  总访问量
 1885
  访问来源
    内部： 9
    外部： 1876
    国内： 1580
    国外： 305

  年访问量
 173
  访问来源
    内部： 1
    外部： 172
    国内： 157
    国外： 16

  月访问量
 27
  访问来源
    内部： 1
    外部： 26
    国内： 22
    国外： 5

访问量

访问量

1. Crystal Structure of the Human Cannabinoid Receptor CB2 [5644]
2. A structurally guided dissection-then-evolution strategy for ligan.. [3246]
3. High-throughput identification of G protein-coupled receptor modul.. [2776]
4. Crystal Structure of the Human Cannabinoid Receptor CB1 [2583]
5. G protein-coupled receptors: structure- and function-based drug di.. [2067]
6. Ligands of Adrenergic Receptors: A Structural Point of View [1730]
7. Crystal structure of a multi-domain human smoothened receptor in c.. [1647]
8. Cryo-EM structures of orphan GPR21 signaling complexes [1631]
9. Molecular Mechanism for Ligand Recognition and Subtype Selectivity.. [1612]
10. Crystal structures of agonist-bound human cannabinoid receptor CB1 [1452]
11. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Pol.. [1396]
12. Structural basis for strychnine activation of human bitter taste r.. [1291]
13. Structural insights into the committed step of bacterial phospholi.. [1290]
14. Salvianolic acids from antithrombotic Traditional Chinese Medicine.. [1277]
15. Cryo-EM structure of constitutively active human Frizzled 7 in com.. [1277]
16. Salvianolic acids from antithrombotic Traditional Chinese Medicine.. [1225]
17. Identification of natural products as novel ligands for the human .. [1220]
18. The activation mechanism and antibody binding mode for orphan GPR2.. [1208]
19. Human GLP-1 receptor transmembrane domain structure in complex wit.. [1180]
20. Crystal structure of the Frizzled 4 receptor in a ligand-free stat.. [1132]
21. Determination of an underneath binding in the transmembrane domain.. [1080]
22. Colocalization Strategy Unveils an Underside Binding Site in the T.. [1080]
23. Novel Variants in GDF9 Gene Affect Promoter Activity and Litter Si.. [1051]
24. MD Simulations Revealing Special Activation Mechanism of Cannabino.. [987]
25. Structural basis of G protein couple receptor polypharmacology [931]
26. Novel Functionalized Cannabinoid Receptor Probes: Development of E.. [878]
27. The structural study of mutation-induced inactivation of human mus.. [859]
28. The structure-based traceless specific fluorescence labeling of th.. [857]
29. Activation and Signaling Mechanism Revealed by Cannabinoid Recepto.. [857]
30. Elucidation of Distinct Modular Assemblies of Smoothened Receptor .. [849]
31. A novel G protein-biased and subtype-selective agonist for a G pro.. [826]
32. A core epitope targeting antibody of SARS-CoV-2 [784]
33. Structural insight into apelin receptor-G protein stoichiometry [772]
34. Structural basis of ligand recognition and self-activation of orph.. [755]
35. Ugi Reaction Mediated Detergent Assembly for Membrane Protein Stud.. [705]
36. Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a.. [670]
37. Determination of the melanocortin-4 receptor structure identifies .. [666]
38. Structure-Based Design of Melanocortin 4 Receptor Ligands Based on.. [643]
39. Structure-Based Ligand Discovery Targeting the Transmembrane Domai.. [641]
40. 人源大麻素受体CB2的晶体结构 [591]
41. Unlocking TAS2R14 activation through intricate multi-ligand bindin.. [562]
42. A computational evaluation of targeted oxidation strategy (TOS) fo.. [539]
43. Bitter taste TAS2R14 activation by intracellular tastants and chol.. [534]
44. Conjugated secondary 12 alpha-hydroxylated bile acids promote live.. [521]
45. Structure-Based Design of Dual-Acting Compounds Targeting Adenosin.. [509]
46. Metabolic Reprogramming in Cancer Is Induced to Increase Proton Pr.. [486]
47. Building the Chordata Olfactory Receptor Database using more than .. [475]
48. Allosterically inhibited PFKL via prostaglandin E2 withholds gluco.. [455]
49. The chordata olfactory receptor database [442]
50. Furin cleavage sites naturally occur in coronaviruses [430]
51. Association analysis between novel variants in LEPR gene and litte.. [429]
52. A framework for Frizzled-G protein coupling and implications to th.. [410]
53. Structure-Based Design of Melanocortin 4 Receptor Ligands based on.. [367]
54. Unveiling the structural mechanisms of nonpeptide ligand recognit.. [325]
55. GPCR Allosteric Modulator Discovery [284]
56. Cryo-EM structure of an activated GPR4-Gs signaling complex [108]
57. Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan R.. [58]
58. Structural basis of β-glucopyranosides salicin recognition by a h.. [50]

下载量

1. Crystal Structure of the Human Cannabinoid Receptor CB2 [1217]
2. High-throughput identification of G protein-coupled receptor modul.. [759]
3. A structurally guided dissection-then-evolution strategy for ligan.. [658]
4. Crystal Structure of the Human Cannabinoid Receptor CB1 [657]
5. Ligands of Adrenergic Receptors: A Structural Point of View [529]
6. Molecular Mechanism for Ligand Recognition and Subtype Selectivity.. [464]
7. Crystal structure of a multi-domain human smoothened receptor in c.. [405]
8. Structural insights into the committed step of bacterial phospholi.. [393]
9. Cryo-EM structure of constitutively active human Frizzled 7 in com.. [384]
10. Cryo-EM structures of orphan GPR21 signaling complexes [366]
11. Salvianolic acids from antithrombotic Traditional Chinese Medicine.. [351]
12. G protein-coupled receptors: structure- and function-based drug di.. [351]
13. Salvianolic acids from antithrombotic Traditional Chinese Medicine.. [344]
14. Novel Variants in GDF9 Gene Affect Promoter Activity and Litter Si.. [290]
15. The activation mechanism and antibody binding mode for orphan GPR2.. [256]
16. MD Simulations Revealing Special Activation Mechanism of Cannabino.. [187]
17. Unlocking TAS2R14 activation through intricate multi-ligand bindin.. [84]
18. Bitter taste TAS2R14 activation by intracellular tastants and chol.. [25]
19. Structure-Based Ligand Discovery Targeting the Transmembrane Domai.. [20]
20. Determination of an underneath binding in the transmembrane domain.. [17]
21. Colocalization Strategy Unveils an Underside Binding Site in the T.. [16]
22. Structural basis for strychnine activation of human bitter taste r.. [16]
23. The chordata olfactory receptor database [16]
24. Crystal structures of agonist-bound human cannabinoid receptor CB1 [15]
25. Allosterically inhibited PFKL via prostaglandin E2 withholds gluco.. [15]
26. Unveiling the structural mechanisms of nonpeptide ligand recognit.. [14]
27. The structure-based traceless specific fluorescence labeling of th.. [13]
28. Crystal structure of the Frizzled 4 receptor in a ligand-free stat.. [11]
29. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Pol.. [9]
30. Structural basis of G protein couple receptor polypharmacology [9]
31. A core epitope targeting antibody of SARS-CoV-2 [9]
32. Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a.. [8]
33. Building the Chordata Olfactory Receptor Database using more than .. [8]
34. A framework for Frizzled-G protein coupling and implications to th.. [8]
35. Human GLP-1 receptor transmembrane domain structure in complex wit.. [7]
36. Cryo-EM structure of an activated GPR4-Gs signaling complex [7]
37. A novel G protein-biased and subtype-selective agonist for a G pro.. [5]
38. Ugi Reaction Mediated Detergent Assembly for Membrane Protein Stud.. [5]
39. Structural insight into apelin receptor-G protein stoichiometry [5]
40. Identification of natural products as novel ligands for the human .. [4]
41. Elucidation of Distinct Modular Assemblies of Smoothened Receptor .. [4]
42. 人源大麻素受体CB2的晶体结构 [3]
43. Structural basis of ligand recognition and self-activation of orph.. [2]
44. Structure-Based Design of Dual-Acting Compounds Targeting Adenosin.. [2]
45. Activation and Signaling Mechanism Revealed by Cannabinoid Recepto.. [1]
46. The structural study of mutation-induced inactivation of human mus.. [1]
47. Determination of the melanocortin-4 receptor structure identifies .. [1]
48. Structure-Based Design of Melanocortin 4 Receptor Ligands Based on.. [1]
49. Novel Functionalized Cannabinoid Receptor Probes: Development of E.. [1]
50. Association analysis between novel variants in LEPR gene and litte.. [1]