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Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7
Authors:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
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Ligands of Adrenergic Receptors: A Structural Point of View 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7
Authors:  Wu, Yiran;  Zeng, Liting;  Zhao, Suwen
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G protein-coupled receptors: structure- and function-based drug discovery 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1
Authors:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz
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Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13752-13765
Authors:  Hu, Tao;  Zheng, Guoxun;  Xue, Dongxiang;  Zhao, Simeng;  Li, Fei
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Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G(s) 期刊论文
CELL RESEARCH, 2021
Authors:  Xu, Lu;  Chen, Bo;  Schihada, Hannes;  Wright, Shane C.;  Turku, Ainoleena
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Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13830-13840
Authors:  Zhao, Fei;  Wu, Yiran;  Zhou, Fang;  Xue, Dongxiang;  Zhao, Simeng
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Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
Authors:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
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Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3870-3884
Authors:  Jiang, Shan;  Iliopoulos-Tsoutsouvas, Christos;  Tong, Fei;  Brust, Christina A.;  Keenan, Catherine M.
Favorite  |  View/Download:116/0  |  Submit date:2021/05/14
Conjugated secondary 12 alpha-hydroxylated bile acids promote liver fibrogenesis 期刊论文
EBIOMEDICINE, 2021, 卷号: 66
Authors:  Xie, Guoxiang;  Jiang, Runqiu;  Wang, Xiaoning;  Liu, Ping;  Zhao, Aihua
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A computational evaluation of targeted oxidation strategy (TOS) for potential inhibition of SARS-CoV-2 by disulfiram and analogues 期刊论文
BIOPHYSICAL CHEMISTRY, 2021, 卷号: 276
Authors:  Xu, Luyan;  Tong, Jiahui;  Wu, Yiran;  Zhao, Suwen;  Li, Bo-Lin
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