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The immune checkpoint molecule B7-H4 regulates R-cell mass and insulin secretion by modulating cholesterol metabolism through Stat5 signalling 期刊论文
MOLECULAR METABOLISM, 2025, 卷号: 91
作者:  Xia, Fangzhen;  Zhang, Ziteng;  Qian, Zhen;  Fang, Xiaoyu;  Wang, Junxue
Adobe PDF(4609Kb)  |  收藏  |  浏览/下载:25/1  |  提交时间:2024/12/17
一种自动化细胞表达重组蛋白的设备 专利
申请号:CN202411396224.9,申请日期: 2024-12-31,类型:发明申请,状态:公开
发明人:  李昂狄;  徐昊;  孙立萍;  刘俊林;  刘志杰
Adobe PDF(947Kb)  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/12/31
Cryo-EM structure of Nipah virus RNA polymerase complex 期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 50
作者:  Yiru Wang;  Lixia Zhao;  Yi Zhang;  Yuhan Wang;  Jiao Tang
收藏  |  浏览/下载:105/1  |  提交时间:2024/11/27
Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease 期刊论文
SCIENCE SIGNALING, 2024, 卷号: 17, 期号: 865
作者:  Barekatain, Mahta;  Johansson, Linda C.;  Lam, Jordy H.;  Chang, Hao;  Sadybekov, Anastasiia V.
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载:32/3  |  提交时间:2024/12/17
Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters? 期刊论文
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 12
作者:  Tsuchitani, Toshiaki;  Kato, Motohiro;  Tomaru, Atsuko;  Aoki, Yasunori;  Sugiyama, Yuichi
Adobe PDF(6271Kb)  |  收藏  |  浏览/下载:25/1  |  提交时间:2024/12/17
Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1
作者:  Zinzula, Luca;  Beck, Florian;  Camasta, Marianna;  Bohn, Stefan;  Liu, Chuan
Adobe PDF(3911Kb)  |  收藏  |  浏览/下载:28/1  |  提交时间:2024/12/17
A novel AAV Vector for gene therapy of RPE-related retinal degenerative diseases via intravitreal delivery 期刊论文
MOLECULAR NEURODEGENERATION, 2024, 卷号: 19, 期号: 1
作者:  Gong, Yajun;  Huang, Xianyu;  Tu, Tianxiang;  Chu, Cenfeng;  Xian, Chunrui
Adobe PDF(1205Kb)  |  收藏  |  浏览/下载:33/3  |  提交时间:2024/12/17
具有芳基取代的环状胺类化合物及其制备方法和用途 专利
申请号:202411576462.8,申请日期: 2024-11-06,类型:发明专利,
发明人:  程建军;  汪胜;  黎慧琼;  唐凌杰;  宴浩瀚
Adobe PDF(261Kb)  |  收藏  |  浏览/下载:55/2  |  提交时间:2024/12/04
Characterizing Y224 conformational flexibility in FtmOx1-catalysis using 19F NMR spectroscopy 期刊论文
CATALYSIS SCIENCE & TECHNOLOGY, 2024
作者:  Wang, Xinye;  Yang, Lingyun;  Wang, Shenlin;  Wang, Jun;  Li, Kelin
Adobe PDF(1564Kb)  |  收藏  |  浏览/下载:21/1  |  提交时间:2024/12/17
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2024
作者:  Ouyang, Qi;  Zhao, Fei;  Ye, Jingjing;  Xu, Mengyang;  Pu, Suyun
Adobe PDF(5147Kb)  |  收藏  |  浏览/下载:56/4  |  提交时间:2024/12/04