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The immune checkpoint molecule B7-H4 regulates R-cell mass and insulin secretion by modulating cholesterol metabolism through Stat5 signalling 期刊论文
MOLECULAR METABOLISM, 2025, 卷号: 91
作者:  Xia, Fangzhen;  Zhang, Ziteng;  Qian, Zhen;  Fang, Xiaoyu;  Wang, Junxue
Adobe PDF(4609Kb)  |  收藏  |  浏览/下载:31/1  |  提交时间:2024/12/17
一种自动化细胞表达重组蛋白的设备 专利
申请号:CN202411396224.9,申请日期: 2024-12-31,类型:发明申请,状态:公开
发明人:  李昂狄;  徐昊;  孙立萍;  刘俊林;  刘志杰
Adobe PDF(947Kb)  |  收藏  |  浏览/下载:30/3  |  提交时间:2024/12/31
Cryo-EM structure of Nipah virus RNA polymerase complex 期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 50
作者:  Yiru Wang;  Lixia Zhao;  Yi Zhang;  Yuhan Wang;  Jiao Tang
收藏  |  浏览/下载:110/1  |  提交时间:2024/11/27
Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters? 期刊论文
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 12
作者:  Tsuchitani, Toshiaki;  Kato, Motohiro;  Tomaru, Atsuko;  Aoki, Yasunori;  Sugiyama, Yuichi
Adobe PDF(6271Kb)  |  收藏  |  浏览/下载:29/1  |  提交时间:2024/12/17
Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1
作者:  Zinzula, Luca;  Beck, Florian;  Camasta, Marianna;  Bohn, Stefan;  Liu, Chuan
Adobe PDF(3911Kb)  |  收藏  |  浏览/下载:32/1  |  提交时间:2024/12/17
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2024
作者:  Ouyang, Qi;  Zhao, Fei;  Ye, Jingjing;  Xu, Mengyang;  Pu, Suyun
Adobe PDF(5147Kb)  |  收藏  |  浏览/下载:60/4  |  提交时间:2024/12/04
Elucidation of DPP-4 involvement in systemic distribution and renal reabsorption of linagliptin by PBPK modeling with a cluster Gauss-Newton method 期刊论文
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 10
作者:  Nakamura, Ryo;  Yoshikado, Takashi;  Aoki, Yasunori;  Sugiyama, Yuichi;  Chiba, Koji
Adobe PDF(4911Kb)  |  收藏  |  浏览/下载:101/4  |  提交时间:2024/11/04
Structure basis of ligand recognition and activation of GPR55 期刊论文
CELL RESEARCH, 2024
作者:  Chang, Hao;  Li, Xiaoting;  Shen, Ling;  Ge, Xuanrui;  Hao, Shuming
Adobe PDF(1392Kb)  |  收藏  |  浏览/下载:116/8  |  提交时间:2024/11/11
昙花提取物及其在调控多巴胺受体通路中的应用 专利
申请号:CN202310317332.1,申请日期: 2024-09-27,类型:发明申请,状态:公开
发明人:  彭瑶;  谈绮文;  刘志杰;  胡霁;  李菲
Adobe PDF(667Kb)  |  收藏  |  浏览/下载:215/5  |  提交时间:2024/09/27
昙花提取物在调控皮肤节律相关通路中的应用 专利
申请号:CN202310307578.0,申请日期: 2024-09-27,类型:发明申请,状态:实质审查
发明人:  彭瑶;  谈绮文;  刘志杰;  周方方
Adobe PDF(1212Kb)  |  收藏  |  浏览/下载:217/5  |  提交时间:2024/09/27