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合作作者[TOP 5]

  • Aoki, Yasunori

    合作成果数：7

  • Toshiaki Tsuchitani

    合作成果数：2

  • Chiba, Koji

    合作成果数：2

  • Nakamura, Ryo

    合作成果数：2

  • Tomaru, Atsuko

    合作成果数：2
Yuichi Sugiyama 非中科院特聘教授
所在学院： iHuman研究所
职务： 特聘教授
研究方向：
备注： --
Yuichi Sugiyama

科研成果

8 2500 132 17 0 2
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 [1] Yoshikado, Takashi,Aoki, Yasunori,Nakamura, Ryo,Shida, Saeko,Sugiyama, Yuichi,&Chiba, Koji.(2025).Elucidating Contributions of Drug Transporters/Enzyme to Nonlinear Pharmacokinetics of Grazoprevir by PBPK Modeling With a Cluster Gauss-Newton Method.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY.浏览/下载:86/3; 被引[WOS]:0; IF:3.1/3.6评论推荐收藏
 [2] Tsuchitani, Toshiaki,Kato, Motohiro,Tomaru, Atsuko,Aoki, Yasunori,&Sugiyama, Yuichi.(2024).Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters?.CTS-CLINICAL AND TRANSLATIONAL SCIENCE,17(12).浏览/下载:255/2; 被引[WOS]:1; IF:3.1/3.6评论推荐收藏
 [3] Nakamura, Ryo,Yoshikado, Takashi,Aoki, Yasunori,Sugiyama, Yuichi,&Chiba, Koji.(2024).Elucidation of DPP-4 involvement in systemic distribution and renal reabsorption of linagliptin by PBPK modeling with a cluster Gauss-Newton method.CTS-CLINICAL AND TRANSLATIONAL SCIENCE,17(10).浏览/下载:307/4; 被引[WOS]:0; IF:3.1/3.6评论推荐收藏
 [4] Aoki, Yasunori,Rowland, Malcom,&Sugiyama, Yuichi.(2024).When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement.FRONTIERS IN PHARMACOLOGY,15.浏览/下载:365/2; 被引[WOS]:0; IF:4.4/5.0评论推荐收藏
 [5] Weiss, H. Markus,Sugiyama, Yuichi,&van Duijn, Esther.(2024).Editorial: Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug development.FRONTIERS IN PHARMACOLOGY,15.浏览/下载:363/1; 被引[WOS]:0; IF:4.4/5.0评论推荐收藏
 [6] Tsuchitani, Toshiaki,Tomaru, Atsuko,Aoki, Yasunori,Ishiguro, Naoki,Tsuda, Yasuhiro,&Sugiyama, Yuichi.(2024).Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY.浏览/下载:300/1; 被引[WOS]:2; IF:3.1/3.6评论推荐收藏
 [7] Aoki, Yasunori,&Sugiyama, Yuichi.(2023).Cluster Gauss-Newton method for a quick approximation of profile likelihood: With application to physiologically-based pharmacokinetic models.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY.浏览/下载:381/0; 被引[WOS]:5; IF:3.1/3.6评论推荐收藏
 [8] Sugiyama, Yuichi,&Aoki, Yasunori.(2023).A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept.DRUG METABOLISM AND DISPOSITION,51(9).浏览/下载:443/119; 被引[WOS]:9; IF:4.4/3.7评论推荐收藏