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合作作者[TOP 5]

  • Aoki, Yasunori

    合作成果数：7

  • Toshiaki Tsuchitani

    合作成果数：2

  • Chiba, Koji

    合作成果数：2

  • Nakamura, Ryo

    合作成果数：2

  • Tomaru, Atsuko

    合作成果数：2
Yuichi Sugiyama 非中科院特聘教授
所在学院： iHuman研究所
职务： 特聘教授
研究方向：
备注： --
Yuichi Sugiyama

科研成果

9 2720 144 24 0 3
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 [1] Asano, Satoshi.,Galetin, Aleksandra.,Tomita, Yoshiko.,Giacomini, Kathleen M..,Chu, Xiaoyan.,...&Sugiyama, Yuichi.(2025).Predicting OCT2/MATEs-Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium).CLINICAL PHARMACOLOGY & THERAPEUTICS.浏览/下载:6/0; 被引[WOS]:0; IF:6.3/6.2评论推荐收藏
 [2] Yoshikado, Takashi,Aoki, Yasunori,Nakamura, Ryo,Shida, Saeko,Sugiyama, Yuichi,&Chiba, Koji.(2025).Elucidating Contributions of Drug Transporters/Enzyme to Nonlinear Pharmacokinetics of Grazoprevir by PBPK Modeling With a Cluster Gauss-Newton Method.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY,14(4),770-780.浏览/下载:100/3; 被引[WOS]:0; IF:3.1/3.6评论推荐收藏
 [3] Tsuchitani, Toshiaki,Kato, Motohiro,Tomaru, Atsuko,Aoki, Yasunori,&Sugiyama, Yuichi.(2024).Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters?.CTS-CLINICAL AND TRANSLATIONAL SCIENCE,17(12).浏览/下载:292/2; 被引[WOS]:1; IF:3.1/3.6评论推荐收藏
 [4] Nakamura, Ryo,Yoshikado, Takashi,Aoki, Yasunori,Sugiyama, Yuichi,&Chiba, Koji.(2024).Elucidation of DPP-4 involvement in systemic distribution and renal reabsorption of linagliptin by PBPK modeling with a cluster Gauss-Newton method.CTS-CLINICAL AND TRANSLATIONAL SCIENCE,17(10).浏览/下载:332/4; 被引[WOS]:0; IF:3.1/3.6评论推荐收藏
 [5] Aoki, Yasunori,Rowland, Malcom,&Sugiyama, Yuichi.(2024).When to consider intra-target microdosing: physiologically based pharmacokinetic modeling approach to quantitatively identify key factors for observing target engagement.FRONTIERS IN PHARMACOLOGY,15.浏览/下载:394/2; 被引[WOS]:0; IF:4.4/5.0评论推荐收藏
 [6] Weiss, H. Markus,Sugiyama, Yuichi,&van Duijn, Esther.(2024).Editorial: Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug development.FRONTIERS IN PHARMACOLOGY,15.浏览/下载:389/1; 被引[WOS]:0; IF:4.4/5.0评论推荐收藏
 [7] Tsuchitani, Toshiaki,Tomaru, Atsuko,Aoki, Yasunori,Ishiguro, Naoki,Tsuda, Yasuhiro,&Sugiyama, Yuichi.(2024).Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY,13(7),1224-1237.浏览/下载:326/1; 被引[WOS]:4; IF:3.1/3.6评论推荐收藏
 [8] Aoki, Yasunori,&Sugiyama, Yuichi.(2023).Cluster Gauss-Newton method for a quick approximation of profile likelihood: With application to physiologically-based pharmacokinetic models.CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY.浏览/下载:401/0; 被引[WOS]:7; IF:3.1/3.6评论推荐收藏
 [9] Sugiyama, Yuichi,&Aoki, Yasunori.(2023).A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept.DRUG METABOLISM AND DISPOSITION,51(9).浏览/下载:480/131; 被引[WOS]:12; IF:4.4/3.7评论推荐收藏