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Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets 预印本
2025
作者:  Song, Minfang;  Ma, Shuai;  Wang, Gong;  Wang, Yukun;  Yang, Zhenzhen
Adobe PDF(2429Kb)  |  收藏  |  浏览/下载:419/7  |  提交时间:2024/10/14
An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes 期刊论文
PROTEIN & CELL, 2025
作者:  Mao, Weijia
Adobe PDF(1142Kb)  |  收藏  |  浏览/下载:38/3  |  提交时间:2025/03/25
Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework 预印本
2025
作者:  Li, Wenhui;  Huang, Baicheng;  Guo, Menghao;  Zeng, Zihan
收藏  |  浏览/下载:52/0  |  提交时间:2025/03/10
Developing safe and efficient CGBE editor based on Cas-embedding strategy 期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2025, 卷号: 10, 期号: 2
作者:  Lin, Tian;  Wang, Xin;  Zhang, Yu;  Li, Guanglei;  Huang, Xingxu
Adobe PDF(4784Kb)  |  收藏  |  浏览/下载:56/2  |  提交时间:2025/03/03
Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis 期刊论文
EMBO JOURNAL, 2024, 卷号: 43, 期号: 24
作者:  Li, Zhean;  Luo, Lingling;  Ju, Xiaohui;  Huang, Shisheng;  Lei, Liqun
Adobe PDF(5941Kb)  |  收藏  |  浏览/下载:74/3  |  提交时间:2025/02/12
Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a 期刊论文
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1
作者:  Liu, Yajing;  Lou, Sensen;  Li, Jinhui;  Liu, Yuanhua;  Huang, Shisheng
Adobe PDF(1307Kb)  |  收藏  |  浏览/下载:307/3  |  提交时间:2024/09/30
Epigenomic landscapes during prefrontal cortex development and aging in rhesus 期刊论文
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 8
作者:  Ning, Chao;  Wu, Xi;  Zhao, Xudong;  Lu, Zongyang;  Yao, Xuelong
Adobe PDF(3955Kb)  |  收藏  |  浏览/下载:312/1  |  提交时间:2024/09/02
用于提高碱基编辑精度的融合蛋白 专利
申请号:CN202410663572.1,申请日期: 2024-08-02,类型:发明申请,状态:实质审查
发明人:  陈佳;  黄行许;  杨力;  杨贝;  李潇飒
Adobe PDF(7832Kb)  |  收藏  |  浏览/下载:310/1  |  提交时间:2024/08/02
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering 期刊论文
CELL RESEARCH, 2024
作者:  Cheng, Peng;  Mao, Cong;  Tang, Jin;  Yang, Sen;  Cheng, Yu
Adobe PDF(5347Kb)  |  收藏  |  浏览/下载:383/3  |  提交时间:2024/07/22
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1
作者:  Liu, Yin;  Liu, Xinyi;  Wei, Dongyi;  Dang, Lu;  Xu, Xiaoran
Adobe PDF(3111Kb)  |  收藏  |  浏览/下载:382/61  |  提交时间:2024/07/02
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