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合作作者[TOP 5]

  • 赵素文

    合作成果数：18

  • 吴屹然

    合作成果数：16

  • 合作成果数：12

  • 陶厚朝

    合作成果数：9

  • Raymond C. Stevens

    合作成果数：8

访问统计


  总访问量
 4292
  访问来源
    内部： 30
    外部： 4262
    国内： 3909
    国外： 383

  年访问量
 492
  访问来源
    内部： 0
    外部： 492
    国内： 466
    国外： 26

  月访问量
 5
  访问来源
    内部： 0
    外部： 5
    国内： 5
    国外： 0

访问量

访问量

1. A structurally guided dissection-then-evolution strategy for ligan.. [3278]
2. Cryo-EM structures of orphan GPR21 signaling complexes [1699]
3. Crystal structure of a multi-domain human smoothened receptor in c.. [1678]
4. Cryo-EM structure of constitutively active human Frizzled 7 in com.. [1292]
5. The activation mechanism and antibody binding mode for orphan GPR2.. [1235]
6. Crystal structure of the Frizzled 4 receptor in a ligand-free stat.. [1145]
7. Determination of an underneath binding in the transmembrane domain.. [1098]
8. Colocalization Strategy Unveils an Underside Binding Site in the T.. [1097]
9. Multiregional profiling of the brain transmembrane proteome uncove.. [923]
10. The structure-based traceless specific fluorescence labeling of th.. [874]
11. Elucidation of Distinct Modular Assemblies of Smoothened Receptor .. [867]
12. Structural Basis for Apelin Control of the Human Apelin Receptor [858]
13. Structural insight into apelin receptor-G protein stoichiometry [788]
14. Structural basis of ligand recognition and self-activation of orph.. [766]
15. 一种卷曲受体7的小分子抑制剂及其制备方法和应用 [670]
16. Structure-Based Ligand Discovery Targeting the Transmembrane Domai.. [658]
17. Structure-Activity Relationship Studies of Hydantoin-Cored Ligands.. [653]
18. The importance of ligands for G protein-coupled receptor stability [644]
19. 一种FZD7鼠源单克隆抗体及其制备方法和应用 [618]
20. Toward the first orphan GPCR structure [600]
21. Cryo-EM structure of human kappa-opioid receptor-G(i) complex boun.. [592]
22. 平滑受体配体及其应用 [573]
23. Structural and Druggability Landscape of Frizzled G Protein-Couple.. [566]
24. 孤儿受体GPR52晶体结构揭示配体结合新机制 [535]
25. Structural insights into the lipid and ligand regulation of a huma.. [530]
26. The versatile binding landscape of the TAAR1 pocket for LSD and ot.. [521]
27. Molecular recognition of the atypical chemokine-like peptide GPR15.. [518]
28. Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therap.. [506]
29. The binding mechanism of an anti-multiple myeloma antibody to the .. [485]
30. Structural Mass Spectrometry Captures Residue-Resolved Comprehensi.. [474]
31. Structural basis of Frizzled 4 in recognition of Dishevelled 2 unv.. [453]
32. Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Ty.. [418]
33. A framework for Frizzled-G protein coupling and implications to th.. [417]
34. Nonlinear relationship between body mass index and serum uric acid.. [412]
35. Association between glycemia risk index and arterial stiffness in .. [380]
36. Unveiling the structural mechanisms of nonpeptide ligand recognit.. [337]
37. 人源Apelin受体与天然配体Apelin的多肽类似物的复合物晶体结构 [330]
38. Crystal structure of the first orphan GPCR [325]
39. 强啡肽单抗融合蛋白的克隆、表达及功能分析 [309]
40. Structural insights into the regulation of monomeric and dimeric a.. [208]
41. 靶向FZD7的单克隆抗体及其制备方法和用途 [80]
42. Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan R.. [58]
43. Association of iodized salt intake with the risk of physical frail.. [43]

下载量

1. A structurally guided dissection-then-evolution strategy for ligan.. [666]
2. Crystal structure of a multi-domain human smoothened receptor in c.. [419]
3. Cryo-EM structure of constitutively active human Frizzled 7 in com.. [394]
4. Cryo-EM structures of orphan GPR21 signaling complexes [381]
5. The activation mechanism and antibody binding mode for orphan GPR2.. [272]
6. Molecular recognition of the atypical chemokine-like peptide GPR15.. [90]
7. The binding mechanism of an anti-multiple myeloma antibody to the .. [80]
8. Structural basis of Frizzled 4 in recognition of Dishevelled 2 unv.. [55]
9. The versatile binding landscape of the TAAR1 pocket for LSD and ot.. [30]
10. Multiregional profiling of the brain transmembrane proteome uncove.. [25]
11. Structure-Based Ligand Discovery Targeting the Transmembrane Domai.. [20]
12. Determination of an underneath binding in the transmembrane domain.. [17]
13. Colocalization Strategy Unveils an Underside Binding Site in the T.. [16]
14. Unveiling the structural mechanisms of nonpeptide ligand recognit.. [14]
15. Structural insights into the regulation of monomeric and dimeric a.. [14]
16. The structure-based traceless specific fluorescence labeling of th.. [13]
17. Structural Mass Spectrometry Captures Residue-Resolved Comprehensi.. [13]
18. Crystal structure of the Frizzled 4 receptor in a ligand-free stat.. [11]
19. Toward the first orphan GPCR structure [9]
20. The importance of ligands for G protein-coupled receptor stability [8]
21. 平滑受体配体及其应用 [8]
22. A framework for Frizzled-G protein coupling and implications to th.. [8]
23. Structural Basis for Apelin Control of the Human Apelin Receptor [6]
24. Structure-Activity Relationship Studies of Hydantoin-Cored Ligands.. [5]
25. Structural insight into apelin receptor-G protein stoichiometry [5]
26. 一种卷曲受体7的小分子抑制剂及其制备方法和应用 [5]
27. Elucidation of Distinct Modular Assemblies of Smoothened Receptor .. [4]
28. Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Ty.. [4]
29. Structural and Druggability Landscape of Frizzled G Protein-Couple.. [3]
30. Structural insights into the lipid and ligand regulation of a huma.. [3]
31. Association between glycemia risk index and arterial stiffness in .. [3]
32. Association of iodized salt intake with the risk of physical frail.. [3]
33. Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therap.. [2]
34. Structural basis of ligand recognition and self-activation of orph.. [2]
35. Nonlinear relationship between body mass index and serum uric acid.. [2]
36. 孤儿受体GPR52晶体结构揭示配体结合新机制 [1]
37. 一种FZD7鼠源单克隆抗体及其制备方法和应用 [1]
38. 人源Apelin受体与天然配体Apelin的多肽类似物的复合物晶体结构 [1]
39. 靶向FZD7的单克隆抗体及其制备方法和用途 [1]