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Fluorine-19 labeling of the tryptophan residues in the G protein-coupled receptor NK1R using the 5-fluoroindole precursor in Pichia pastoris expression 期刊论文
JOURNAL OF BIOMOLECULAR NMR, 2024
作者:  Pan, Benxun;  Guo, Canyong;  Liu, Dongsheng;  Wuthrich, Kurt
Adobe PDF(2252Kb)  |  收藏  |  浏览/下载:133/1  |  提交时间:2024/05/14
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023
作者:  Li, Cuixia;  Wu, Yiran;  Wang, Wenli;  Xu, Lu;  Zhou, Yan
Adobe PDF(4644Kb)  |  收藏  |  浏览/下载:349/9  |  提交时间:2023/09/25
Inhibitory to non-inhibitory evolution of the ? subunit of the F1FO-ATPase of Paracoccus denitrificans and a-proteobacteria as related to mitochondrial endosymbiosis 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 卷号: 10
作者:  Mendoza-Hoffmann, Francisco;  Yang, Lingyun;  Buratto, Damiano;  Brito-Sanchez, Jorge;  Garduno-Javier, Gilberto
Adobe PDF(4969Kb)  |  收藏  |  浏览/下载:286/63  |  提交时间:2023/09/18
Selective polypeptide ligand binding to the extracellular surface of the transmembrane domains of the class B GPCRs GLP-1R and GCGR 期刊论文
ISCIENCE, 2023, 卷号: 26, 期号: 6
作者:  Wang, Huixia;  Hu, Wanhui;  Xu, Tiandan;  Yuan, Ya;  Liu, Dongsheng
Adobe PDF(6452Kb)  |  收藏  |  浏览/下载:294/2  |  提交时间:2023/08/21
Cryo-EM structure of human kappa-opioid receptor-G(i) complex bound to an endogenous agonist dynorphin A 期刊论文
PROTEIN & CELL, 2023, 卷号: 14, 期号: 6
作者:  Chen, Yuxiang;  Chen, Bo;  Wu, Tingting;  Zhou, Fangfang;  Xu, Fei
Adobe PDF(8922Kb)  |  收藏  |  浏览/下载:304/0  |  提交时间:2023/07/11
Solvent accessibility of a GPCR transmembrane domain probed by in-membrane chemical modification (IMCM) 期刊论文
FEBS LETTERS, 2023
作者:  Dandan Feng;  Guanru Feng;  Yanzhuo Song;  Kurt Wuthrich
Adobe PDF(571Kb)  |  收藏  |  浏览/下载:246/0  |  提交时间:2023/09/22
Adenosine A2AReceptor (A2AAR) Ligand Screening Using the 19F-NMR Probe FPPA 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 28, 页码: 15061-15064
作者:  Zhang, Jinfeng;  Feng, Dandan;  Cheng, Jianjun;  Wüthrich, Kurt
Adobe PDF(1667Kb)  |  收藏  |  浏览/下载:302/1  |  提交时间:2023/07/28
Transition-Linker Containing Detergents for Membrane Protein Studies 期刊论文
CHEMISTRY - A EUROPEAN JOURNAL, 2022
作者:  Luo, Weiling;  Yang, Meifang;  Zhao, Yitian;  Wang, Huixia;  Yang, Xiaodi
Adobe PDF(2541Kb)  |  收藏  |  浏览/下载:462/3  |  提交时间:2022/11/04
一种FZD7鼠源单克隆抗体及其制备方法和应用 专利
申请号:CN202110341336.4,申请日期: 2022-10-04,类型:发明申请,状态:实质审查
发明人:  徐菲;  徐鹭;  吴亭亭
Unknown(969Kb)  |  收藏  |  浏览/下载:442/0  |  提交时间:2022/10/04
GPCR structural characterization by NMR spectroscopy in solution 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 9
作者:  Yang, Lingyun;  Liu, Dongsheng;  Wuethrich, Kurt
Adobe PDF(1243Kb)  |  收藏  |  浏览/下载:338/2  |  提交时间:2023/01/16