Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group

doi:10.1039/c9ra00749k

	Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group
	Cong, Zhanqing1,2,3 ; Gao, Feng 1,2; Liu, Hong1,2,3
	2019
发表期刊	RSC ADVANCES (IF:3.9[JCR-2023],3.9[5-Year])
ISSN	2046-2069
卷号	9 期号:19 页码:10820-10824
发表状态	已发表
DOI	10.1039/c9ra00749k
摘要	The nickel(ii)-catalyzed ortho-arylation of unactivated C-H bonds utilizing amino acids as directing groups with aryl iodides or bromides as coupling electrophiles is described. This protocol features excellent mono-selectivity, good regioselectivity, and wide functional group tolerance. Additionally, the obtained products bearing a biaryl motif and an amino acid represent bioactive molecules with wide bioactivities.
收录类别	SCI ; SCIE ; EI
语种	英语
资助项目	Major Project of Chinese National Programs for Fundamental Research and Development[2015CB910304]
WOS研究方向	Chemistry
WOS类目	Chemistry, Multidisciplinary
WOS记录号	WOS:000465297300044
出版者	ROYAL SOC CHEMISTRY
EI入藏号	20191606792386
EI主题词	Amino acids ; Aromatic compounds ; Bioactivity ; Catalysis
EI分类号	Medicine and Pharmacology:461.6 ; Chemical Reactions:802.2 ; Organic Compounds:804.1
WOS关键词	BETA-C(SP(3))-H ARYLATION ; INTRAMOLECULAR AMINATION ; C(SP(2))-H BONDS ; C(SP(3))-H BONDS ; FUNCTIONALIZATION ; DERIVATIVES ; ACTIVATION ; BENZAMIDES ; 8-AMINOQUINOLINE ; THIOLATION
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/37516
专题	生命科学与技术学院_硕士生生命科学与技术学院_特聘教授组_柳红组
通讯作者	Liu, Hong
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 3.ShanghaiTech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China
第一作者单位	生命科学与技术学院
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Cong, Zhanqing,Gao, Feng,Liu, Hong. Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group[J]. RSC ADVANCES,2019,9(19):10820-10824.
APA	Cong, Zhanqing,Gao, Feng,&Liu, Hong.(2019).Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group.RSC ADVANCES,9(19),10820-10824.
MLA	Cong, Zhanqing,et al."Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C-H bonds utilizing amino acids as a directing group".RSC ADVANCES 9.19(2019):10820-10824.