Differentiated demographic histories and local adaptations between Sherpas and Tibetans

doi:10.1186/s13059-017-1242-y

	Differentiated demographic histories and local adaptations between Sherpas and Tibetans
	Zhang, Chao 1,2; Lu, Yan 1; Feng, Qidi 1,2; Wang, Xiaoji1,2,3 ; Lou, Haiyi 1; Liu, Jiaojiao1,2,3 ; Ning, Zhilin 1,2; Yuan, Kai 1,2; Wang, Yuchen 1,2; Zhou, Ying 1,2; Deng, Lian 1,2; Liu, Lijun 4; Yang, Yajun 5,6; Li, Shilin 5,6; Ma, Lifeng 4; Zhang, Zhiying 4; Jin, Li 5,6; Su, Bing 7; Kang, Longli 4; Xu, Shuhua1,2,3,8
	2017-06-15
发表期刊	GENOME BIOLOGY (IF:10.1[JCR-2023],16.5[5-Year])
ISSN	1474-760X
卷号	18
发表状态	已发表
DOI	10.1186/s13059-017-1242-y
摘要	Background: The genetic relationships reported by recent studies between Sherpas and Tibetans are controversial. To gain insights into the population history and the genetic basis of high-altitude adaptation of the two groups, we analyzed genome-wide data in 111 Sherpas (Tibet and Nepal) and 177 Tibetans (Tibet and Qinghai), together with available data from present-day human populations.
关键词	Sherpa Tibetan Next-generation sequencing High-altitude adaptation Population history Gene flow
URL	查看原文
收录类别	SCI
语种	英语
资助项目	Science and Technology Commission of Shanghai Municipality (STCSM)[14YF1406800] ; Science and Technology Commission of Shanghai Municipality (STCSM)[16YF1413900]
WOS研究方向	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS类目	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS记录号	WOS:000403323600002
出版者	BIOMED CENTRAL LTD
WOS关键词	HIGH-ALTITUDE ADAPTATION ; GENETIC-EVIDENCE ; HAPLOTYPE STRUCTURE ; POSITIVE SELECTION ; GENOME SEQUENCES ; NORTHERN CHINA ; NITRIC-OXIDE ; HYPOXIA ; HIMALAYAS ; ORIGINS
原始文献类型	Article
通讯作者	Xu, Shuhua
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/2914
专题	生命科学与技术学院生命科学与技术学院_特聘教授组_徐书华组生命科学与技术学院_硕士生生命科学与技术学院_博士生
通讯作者	Xu, Shuhua
作者单位	1.Chinese Acad Sci, Max Planck Independent Res Grp Populat Genom, CAS MPG Partner Inst Computat Biol PICB, Key Lab Computat Biol,Shanghai Inst Biol Sci, Shanghai 200031, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 4.Xizang Minzu Univ, Sch Med, Key Lab Mol Genet Mech & Intervent Res High Altit, Xianyang 712082, Shaanxi, Peoples R China 5.Fudan Univ, State Key Lab Genet Engn, Shanghai 200433, Peoples R China 6.Fudan Univ, Minist Educ MOE, Key Lab Contemporary Anthropol, Sch Life Sci, Shanghai 200433, Peoples R China 7.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Peoples R China 8.Collaborat Innovat Ctr Genet & Dev, Shanghai 200438, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Zhang, Chao,Lu, Yan,Feng, Qidi,et al. Differentiated demographic histories and local adaptations between Sherpas and Tibetans[J]. GENOME BIOLOGY,2017,18.
APA	Zhang, Chao.,Lu, Yan.,Feng, Qidi.,Wang, Xiaoji.,Lou, Haiyi.,...&Xu, Shuhua.(2017).Differentiated demographic histories and local adaptations between Sherpas and Tibetans.GENOME BIOLOGY,18.
MLA	Zhang, Chao,et al."Differentiated demographic histories and local adaptations between Sherpas and Tibetans".GENOME BIOLOGY 18(2017).