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Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282
作者:  Qibang Sui;  Yuanyang Zhou;  Manjia Li;  Dan Wang;  Rongrong Cui
Adobe PDF(7302Kb)  |  收藏  |  浏览/下载:65/12  |  提交时间:2024/11/27
Routes to Molecular Glue Degrader Discovery 期刊论文
TRENDS IN BIOCHEMICAL SCIENCES, 2025
作者:  Liu YF(刘艳芬);  Bai JY(白洁云);  Li D(李栋);  Cang Y(仓勇)
收藏  |  浏览/下载:67/0  |  提交时间:2024/12/03
一种噻唑烷二酮类化合物、其药物组合物和其用途 专利
申请号:CN202410806451.8,申请日期: 2024-12-24,类型:发明申请,状态:公开
发明人:  范国平;  白芳;  许红涛;  祝献民;  王林
Adobe PDF(2056Kb)  |  收藏  |  浏览/下载:18/1  |  提交时间:2024/12/24
Cryo-EM structure of Nipah virus RNA polymerase complex 期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 50
作者:  Yiru Wang;  Lixia Zhao;  Yi Zhang;  Yuhan Wang;  Jiao Tang
收藏  |  浏览/下载:90/1  |  提交时间:2024/11/27
Multiple-Wave Admixture and Adaptive Evolution of the Pamirian Wakhi People 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2024, 卷号: 41, 期号: 12
作者:  Xu, Wanxing;  Liu, Jiaojiao;  Zhang, Xiaoxi;  Wen, Jia;  Feng, Qidi
收藏  |  浏览/下载:24/0  |  提交时间:2024/12/23
Activation of imprinted gene Pw1 promotes cardiac fibrosis after ischemic injury 期刊论文
CIRCULATION, 2024
作者:  Kou S(叩珊);  Lu ZK(卢正开);  Deng DF(邓德方);  Ye M(叶敏);  Sui Y(隋雨)
Adobe PDF(13390Kb)  |  收藏  |  浏览/下载:118/11  |  提交时间:2024/12/04
A TT1-SCE1 module integrates ubiquitination and SUMOylation to regulate heat tolerance in rice 期刊论文
MOLECULAR PLANT, 2024, 卷号: 17, 期号: 12
作者:  Yu, Hong-Xiao;  Cao, Ying-Jie;  Yang, Yi-Bing;  Shan, Jun-Xiang;  Ye, Wang-Wei
Adobe PDF(4409Kb)  |  收藏  |  浏览/下载:14/1  |  提交时间:2024/12/17
Heat Acclimation in Mice Requires Preoptic BDNF Neurons and Postsynaptic Potentiation. 期刊论文
CELL RESEARCH, 2024
作者:  Chen BT(陈宝婷);  Gao CC(高翠翠);  Shen W(沈伟)
JPEG(326Kb)  |  收藏  |  浏览/下载:56/2  |  提交时间:2024/11/28
MAI-TargetFisher: A proteome-wide drug target prediction method synergetically enhanced by artificial intelligence and physical modeling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024
作者:  Li, Shiwei;  Ren, Pengxuan;  Wang, Lin;  Han, Qilei;  Li, Fenglei
收藏  |  浏览/下载:69/0  |  提交时间:2024/12/02
Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader 期刊论文
CELL DEATH & DISEASE, 2024
作者:  Chen, Li;  Zou, Yahui;  Sun, Renhong;  Huang, Mei;  Zhu, Xiaotong
收藏  |  浏览/下载:67/0  |  提交时间:2024/12/03