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ShanghaiTech University Knowledge Management System
| Intrinsic heterogeneity in axon regeneration | |
| 2022-11 | |
| 发表期刊 | BIOCHEMICAL SOCIETY TRANSACTIONS (IF:3.8[JCR-2023],4.3[5-Year]) |
| ISSN | 0300-5127 |
| EISSN | 1470-8752 |
| 发表状态 | 已发表 |
| DOI | 10.1042/BST20220624 |
| 摘要 | The nervous system is composed of a variety of neurons and glial cells with different morphology and functions. In the mammalian peripheral nervous system (PNS) or the lower vertebrate central nervous system (CNS), most neurons can regenerate extensively after axotomy, while the neurons in the mammalian CNS possess only limited regenera-tive ability. This heterogeneity is common within and across species. The studies about the transcriptomes after nerve injury in different animal models have revealed a series of molecular and cellular events that occurred in neurons after axotomy. However, responses of various types of neurons located in different positions of individuals were different remarkably. Thus, researchers aim to find the key factors that are conducive to regeneration, so as to provide the molecular basis for solving the regeneration difficulties after CNS injury. Here we review the heterogeneity of axonal regeneration among different cell subtypes in different animal models or the same organ, emphasizing the importance of comparative studies within and across species. |
| URL | 查看原文 |
| 收录类别 | SCI ; SCIE |
| 语种 | 英语 |
| 资助项目 | [32130035] ; [92168107] ; [2021ZD0202500] ; [QYZDJ-SSW-SMC025] ; [2018SHZDZX05] |
| WOS研究方向 | Biochemistry & Molecular Biology |
| WOS类目 | Biochemistry & Molecular Biology |
| WOS记录号 | WOS:000886865300001 |
| 出版者 | PORTLAND PRESS LTD |
| 引用统计 | 正在获取...
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| 文献类型 | 期刊论文 |
| 条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/251702 |
| 专题 | 生命科学与技术学院_博士生 生命科学与技术学院_硕士生 生命科学与技术学院_PI研究组_罗振革组 |
| 通讯作者 | Fu, Xiu-Qing; Luo, Zhen-Ge |
| 作者单位 | 1.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 第一作者单位 | 生命科学与技术学院 |
| 通讯作者单位 | 生命科学与技术学院 |
| 第一作者的第一单位 | 生命科学与技术学院 |
| 推荐引用方式 GB/T 7714 | Fu, Xiu-Qing,Zhan, Wen-Rong,Tian, Wei-Ya,et al. Intrinsic heterogeneity in axon regeneration[J]. BIOCHEMICAL SOCIETY TRANSACTIONS,2022. |
| APA | Fu, Xiu-Qing,Zhan, Wen-Rong,Tian, Wei-Ya,Cao, Dong-Dong,&Luo, Zhen-Ge.(2022).Intrinsic heterogeneity in axon regeneration.BIOCHEMICAL SOCIETY TRANSACTIONS. |
| MLA | Fu, Xiu-Qing,et al."Intrinsic heterogeneity in axon regeneration".BIOCHEMICAL SOCIETY TRANSACTIONS (2022). |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
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