Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector

doi:10.1016/j.cell.2021.09.009

	Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector
	Gao, Mingjun 1; He, Yang 1; Yin, Xin 1,9; Zhong, Xiangbin 1,10,11; Yan, Bingxiao 1; Wu, Yue 1; Chen, Jin 1; Li, Xiaoyuan2 ; Zhai, Keran 1; Huang, Yifeng 1; Gong, Xiangyu 1; Chang, Huizhong 1; Xie, Shenghan2 ; Liu, Jiyun 1; Yue, Jiaxing 3; Xu, Jianlong 4; Zhang, Guiquan 5; Deng, Yiwen 1; Wang, Ertao 1; Tharreau, Didier 6; Wang, Guo-Liang 7; Yang, Weibing 1,8; He, Zuhua 1
	2021
发表期刊	CELL (IF:45.5[JCR-2023],49.0[5-Year])
ISSN	0092-8674
EISSN	1097-4172
卷号	184 期号:21 页码:5391-+
DOI	10.1016/j.cell.2021.09.009
摘要	Plant immunity is activated upon pathogen perception and often affects growth and yield when it is constitutively active. How plants fine-tune immune homeostasis in their natural habitats remains elusive. Here, we discover a conserved immune suppression network in cereals that orchestrates immune homeostasis, centering on a Ca2+-sensor, RESISTANCE OF RICE TO DISEASES1 (ROD1). ROD1 promotes reactive oxygen species (ROS) scavenging by stimulating catalase activity, and its protein stability is regulated by ubiquitination. ROD1 disruption confers resistance to multiple pathogens, whereas a natural ROD1 allele prevalent in indica rice with agroecology-specific distribution enhances resistance without yield penalty. The fungal effector AvrPiz-t structurally mimics ROD1 and activates the same ROS-scavenging cascade to suppress host immunity and promote virulence. We thus reveal a molecular framework adopted by both host and pathogen that integrates Ca2+ sensing and ROS homeostasis to suppress plant immunity, suggesting a principle for breeding disease-resistant, high-yield crops.
收录类别	SCIE
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology
WOS类目	Biochemistry & Molecular Biology ; Cell Biology
WOS记录号	WOS:000714065000017
出版者	CELL PRESS
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/130325
专题	生命科学与技术学院_博士生生命科学与技术学院_硕士生
通讯作者	Zhong, Xiangbin; Yang, Weibing; He, Zuhua
作者单位	1.Chinese Acad Sci, Inst Plant Physiol & Ecol, CAS Ctr Excellence Mol Plant Sci, Natl Key Lab Plant Mol Genet, Shanghai 200032, Peoples R China; 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China; 3.Sun Yat Sen Univ, Ctr Canc, Guangzhou 510060, Peoples R China; 4.Chinese Acad Agr Sci, Insititute Crop Sci, Beijing 100081, Peoples R China; 5.South China Agr Univ, Coll Agr, Guangzhou 510642, Peoples R China; 6.MUSE, Montpellier SupAgro, IRD, PHIM,CIRAD,INRAE, Montpellier 05, France; 7.Ohio State Univ, Dept Plant Pathol, Columbus, OH 43210 USA; 8.Chinese Acad Sci, Inst Plant Physiol & Ecol, CAS JIC Ctr Excellence Plant & Microbial Sci, Shanghai 200032, Peoples R China; 9.Chinese Acad Sci, Inst Microbiol, State Key Lab Plant Genom, Beijing 100101, Peoples R China; 10.Fujian Agr & Forestry Univ, Coll Resources & Environm, Fuzhou 350002, Peoples R China; 11.Fujian Agr & Forestry Univ, Haixia Inst Sci & Technol, Fuzhou 350002, Peoples R China
推荐引用方式 GB/T 7714	Gao, Mingjun,He, Yang,Yin, Xin,et al. Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector[J]. CELL,2021,184(21):5391-+.
APA	Gao, Mingjun.,He, Yang.,Yin, Xin.,Zhong, Xiangbin.,Yan, Bingxiao.,...&He, Zuhua.(2021).Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector.CELL,184(21),5391-+.
MLA	Gao, Mingjun,et al."Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector".CELL 184.21(2021):5391-+.