A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance

doi:10.1038/s42003-021-02686-x

	A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance
	Zhang, Yi-Min 1,2,3; Yu, Hong-Xiao 1,2,3; Ye, Wang-Wei 1,2; Shan, Jun-Xiang 1,2; Dong, Nai-Qian 1,2; Guo, Tao 1,2; Xiang, You-Huang 1,2,3; Zhang, Hai1,2,4 ; Yang, Yi-Bing 1,2,3; Li, Ya-Chao1,2,4 ; Zhao, Huai-Yu 1,2,3; Lu, Zi-Qi1,2,4 ; Guo, Shuang-Qin 1,2,3; Lei, Jie-Jie 1,2,3; Liao, Ben1,2,4 ; Mu, Xiao-Rui 1,2,3; Cao, Ying-Jie 1,2,3; Yu, Jia-Jun1,2,4 ; Lin, Hong-Xuan1,2,3,4,5
	2021-10-07
发表期刊	COMMUNICATIONS BIOLOGY (IF:5.2[JCR-2023],5.6[5-Year])
EISSN	2399-3642
卷号	4 期号:1
DOI	10.1038/s42003-021-02686-x
摘要	Zhang et al. report QTL GS3.1 as regulating rice grain size via metabolic flux allocation between two branches of phenylpropanoid metabolism. Their results identify the biosynthetic pathway for grain size regulation via a multidrug and toxic compounds extrusion transporter, and demonstrate enlarged grains, reduced flavonoid content, and increased lignin content in the panicles with GS3.1. Grain size is a key component trait of grain weight and yield. Numbers of quantitative trait loci (QTLs) have been identified in various bioprocesses, but there is still little known about how metabolism-related QTLs influence grain size and yield. The current study report GS3.1, a QTL that regulates rice grain size via metabolic flux allocation between two branches of phenylpropanoid metabolism. GS3.1 encodes a MATE (multidrug and toxic compounds extrusion) transporter that regulates grain size by directing the transport of p-coumaric acid from the p-coumaric acid biosynthetic metabolon to the flavonoid biosynthetic metabolon. A natural allele of GS3.1 was identified from an African rice with enlarged grains, reduced flavonoid content and increased lignin content in the panicles. Notably, the natural allele of GS3.1 caused no alterations in other tissues and did not affect stress tolerance, revealing an ideal candidate for breeding efforts. This study uncovers insights into the regulation of grain size though metabolic-flux distribution. In this way, it supports a strategy of enhancing crop yield without introducing deleterious side effects on stress tolerance mechanisms.
URL	查看原文
收录类别	SCIE
语种	英语
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Science & Technology - Other Topics
WOS类目	Biology ; Multidisciplinary Sciences
WOS记录号	WOS:000704983200007
出版者	NATURE PORTFOLIO
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/128415
专题	生命科学与技术学院_博士生生命科学与技术学院_特聘教授组_林鸿宣组生命科学与技术学院_硕士生
通讯作者	Lin, Hong-Xuan
作者单位	1.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Shanghai Inst Plant Physiol & Ecol, Natl Key Lab Plant Mol Genet, Shanghai 200032, Peoples R China; 2.Chinese Acad Sci, Collaborat Innovat Ctr Genet & Dev, Shanghai Inst Plant Physiol & Ecol, Shanghai 200032, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 4.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China; 5.Guangdong Lab Lingnan Modern Agr, Guangzhou 510642, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Zhang, Yi-Min,Yu, Hong-Xiao,Ye, Wang-Wei,et al. A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance[J]. COMMUNICATIONS BIOLOGY,2021,4(1).
APA	Zhang, Yi-Min.,Yu, Hong-Xiao.,Ye, Wang-Wei.,Shan, Jun-Xiang.,Dong, Nai-Qian.,...&Lin, Hong-Xuan.(2021).A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance.COMMUNICATIONS BIOLOGY,4(1).
MLA	Zhang, Yi-Min,et al."A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance".COMMUNICATIONS BIOLOGY 4.1(2021).