Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor

doi:10.1016/j.scr.2021.102173

	Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor
	Zhang, Wenxin1,2 ; Hua, Yishi 1; Di, Weihao1,2 ; Guo, Jinghui1,2 ; Dai, Qiuting1,2 ; Zhao, Jian1,2 ; Zhang, Bei 3; Wang, Ying1
	2021-03
发表期刊	STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year])
ISSN	1873-5061
EISSN	1876-7753
卷号	51
发表状态	已发表
DOI	10.1016/j.scr.2021.102173
摘要	Peripheral blood mononuclear cells (PBMC) were donated by a healthy 61-year old Chinese Han female. Human OKSM (OCT3/4, KLF4 SOX2, and c-MYC) transcription factors were used to reprogram her PBMCs with the non-integrating episomal vector system. Immunocytochemistry for pluripotency makers confirmed the pluripotency of transgene-free iPSCs and their ability to differentiate spontaneously three germ layers in vitro. The iPSC line displayed a normal karyotype. Our model offers the possibility to be used a control in pathological mechanism studies.
收录类别	SCIE
语种	英语
WOS研究方向	Cell Biology ; Biotechnology & Applied Microbiology
WOS类目	Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology
WOS记录号	WOS:000629039100023
出版者	ELSEVIER
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/126172
专题	生命科学与技术学院_硕士生生命科学与技术学院_博士生免疫化学研究所_PI研究组_赵简组
通讯作者	Zhang, Bei; Wang, Ying
作者单位	1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai, Peoples R China; 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China; 3.Tongji Univ, Shanghai East Hosp, Dept Neurol, Sch Med, Shanghai, Peoples R China
第一作者单位	免疫化学研究所; 生命科学与技术学院
通讯作者单位	免疫化学研究所
第一作者的第一单位	免疫化学研究所
推荐引用方式 GB/T 7714	Zhang, Wenxin,Hua, Yishi,Di, Weihao,et al. Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor[J]. STEM CELL RESEARCH,2021,51.
APA	Zhang, Wenxin.,Hua, Yishi.,Di, Weihao.,Guo, Jinghui.,Dai, Qiuting.,...&Wang, Ying.(2021).Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor.STEM CELL RESEARCH,51.
MLA	Zhang, Wenxin,et al."Generation of a human induced pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han healthy female donor".STEM CELL RESEARCH 51(2021).