Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele

doi:10.1016/j.scr.2021.102198

	Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele
	Guo, Jinghui1,2 ; Di, Weihao1,2 ; Zhang, Wenxin1,2 ; Dai, Qiuting1,2 ; Zhao, Jian1,2 ; Deng, Yulei 3; Wang, Ying1
	2021-03
发表期刊	STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year])
ISSN	1873-5061
EISSN	1876-7753
卷号	51
发表状态	已发表
DOI	10.1016/j.scr.2021.102198
摘要	Induced pluripotent stem cells play vitally essential roles in regenerative medicines for disease modeling and drug screening. Here, we successfully generated an iPSC line from PBMC of a 60-year-old female with mild cognitive impairment in an APOE 4/4 background to better understand studies relating to MCI and other cognitive diseases. In the newly-developed hiPSC line SIAISi009-A, all pluripotent markers were well expressed. Moreover, cells displayed a normal karyotype and have differentiation potential proven by in vitro trilineage differentiation method.
收录类别	SCIE
语种	英语
WOS研究方向	Cell Biology ; Biotechnology & Applied Microbiology
WOS类目	Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology
WOS记录号	WOS:000629039100042
出版者	ELSEVIER
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/126170
专题	生命科学与技术学院_硕士生生命科学与技术学院_博士生免疫化学研究所_PI研究组_赵简组
通讯作者	Deng, Yulei; Wang, Ying
作者单位	1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai, Peoples R China; 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China; 3.Jiaotong Univ, Shanghai Ruijin Hosp, Sch Med, Neurol Dept, Shanghai, Peoples R China
第一作者单位	免疫化学研究所; 生命科学与技术学院
通讯作者单位	免疫化学研究所
第一作者的第一单位	免疫化学研究所
推荐引用方式 GB/T 7714	Guo, Jinghui,Di, Weihao,Zhang, Wenxin,et al. Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele[J]. STEM CELL RESEARCH,2021,51.
APA	Guo, Jinghui.,Di, Weihao.,Zhang, Wenxin.,Dai, Qiuting.,Zhao, Jian.,...&Wang, Ying.(2021).Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele.STEM CELL RESEARCH,51.
MLA	Guo, Jinghui,et al."Generation of an induced pluripotent stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild cognitive impairment (MCI) having two copies of APOE4/4 allele".STEM CELL RESEARCH 51(2021).