Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male

doi:10.1016/j.scr.2021.102186

	Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male
	Guo, Jinghui1,2 ; Fang, Fang 3; Dai, Qiuting1,2 ; Zhang, Wenxin1,2 ; Di, Weihao1,2 ; Hu, Jiaan 3; Zhao, Jian1,2 ; Cao, Jiumei 3; Wang, Ying1
	2021-04
发表期刊	STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year])
ISSN	1873-5061
EISSN	1876-7753
卷号	52
发表状态	已发表
DOI	10.1016/j.scr.2021.102186
摘要	As the global median population age increases, neurological diseases associated with aging pose significant challenges to human health. Appropriate modeling systems can be useful tools to better understand the mechanism of age-related neuronal degeneration diseases. Here, we successfully generated an iPSC-derived modeling system of an 82-year-old healthy man, this newly established line showed that all pluripotent markers were expressed, and the differentiation potential was confirmed by trilineage differentiation. STR profiling proved the cell line identity, and G-binding showed the normal karyotype.
收录类别	SCIE
语种	英语
WOS研究方向	Cell Biology ; Biotechnology & Applied Microbiology
WOS类目	Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology
WOS记录号	WOS:000631896900002
出版者	ELSEVIER
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/126147
专题	生命科学与技术学院_硕士生生命科学与技术学院_博士生免疫化学研究所_PI研究组_赵简组
通讯作者	Cao, Jiumei; Wang, Ying
作者单位	1.Shanghai Tech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai, Peoples R China; 2.Shanghai Tech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China; 3.Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Geriatr, Sch Med, Shanghai, Peoples R China
第一作者单位	免疫化学研究所; 生命科学与技术学院
通讯作者单位	免疫化学研究所
第一作者的第一单位	免疫化学研究所
推荐引用方式 GB/T 7714	Guo, Jinghui,Fang, Fang,Dai, Qiuting,et al. Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male[J]. STEM CELL RESEARCH,2021,52.
APA	Guo, Jinghui.,Fang, Fang.,Dai, Qiuting.,Zhang, Wenxin.,Di, Weihao.,...&Wang, Ying.(2021).Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male.STEM CELL RESEARCH,52.
MLA	Guo, Jinghui,et al."Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male".STEM CELL RESEARCH 52(2021).