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Design and synthesis of Thieno[3, 2-b]pyridinone derivatives exhibiting potent activities against Mycobacterium tuberculosis in vivo by targeting Enoyl-ACP reductase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 279
作者:  Liang, Lihong;  Liu, Zhiyong;  Chen, Jie;  Zha, Qin;  Zhou, Yihuan
Adobe PDF(1929Kb)  |  收藏  |  浏览/下载:155/2  |  提交时间:2024/09/30
Not only ClpC1 but also ClpX are drug targets of Ilamycins 预印本
2024
作者:  Gao, Yamin;  Fang, Cuiting;  Zhou, Biao;  Hameed, H.M. Adnan;  Sun, Changli
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载:222/30  |  提交时间:2024/08/14
Cryo-EM structures of a prokaryotic heme transporter CydDC 期刊论文
PROTEIN & CELL, 2023
作者:  Zhu, Chen;  Shi, Yanfeng;  Yu, Jing;  Zhao, Wenhao;  Li, Lingqiao
Adobe PDF(795Kb)  |  收藏  |  浏览/下载:879/175  |  提交时间:2023/07/11
MMPL3抑制剂,其组合物及其用途 专利
申请号:ZA202104192,申请日期: 2022-07-27,类型:发明授权,状态:授权
发明人:  Rao Zihe;  Li Jun;  Zhang Bing;  Yang Haitao
收藏  |  浏览/下载:232/0  |  提交时间:2023/10/01
Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 1608
作者:  Wang, Haofeng;  Xiao, Yunjie;  Chen, Xia;  Zhang, Mengwen;  Sun, Guangxin
Adobe PDF(8913Kb)  |  收藏  |  浏览/下载:813/201  |  提交时间:2022/11/08
抗结核药物靶点的结构研究进展 期刊论文
自然杂志, 2021, 卷号: 43, 期号: 5, 页码: 335-342
作者:  陈晓博;  李俊
Adobe PDF(2973Kb)  |  收藏  |  浏览/下载:195/0  |  提交时间:2022/12/14
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6496, 页码: 1211
作者:  Zhang, Lu;  Zhao, Yao;  Gao, Yan;  Wu, Lijie;  Gao, Ruogu
Adobe PDF(1981Kb)  |  收藏  |  浏览/下载:1143/34  |  提交时间:2020/06/16
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6492, 页码: 779-+
作者:  Gao, Yan;  Yan, Liming;  Huang, Yucen;  Liu, Fengjiang;  Zhao, Yao
Adobe PDF(963Kb)  |  收藏  |  浏览/下载:2995/577  |  提交时间:2020/04/17
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2) 期刊论文
PROTEIN & CELL, 2020, 卷号: 11, 期号: 7, 页码: 505-517
作者:  Zhang, Lu;  Zhao, Yao;  Gao, Ruogu;  Li, Jun;  Yang, Xiuna
Adobe PDF(5000Kb)  |  收藏  |  浏览/下载:620/10  |  提交时间:2020/05/25
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity 期刊论文
NATURE, 2020, 卷号: 577, 期号: 7792, 页码: 682-+
作者:  Wang, Lin;  Wu, Juehui;  Li, Jun;  Yang, Hua;  Tang, Tianqi
Adobe PDF(6556Kb)  |  收藏  |  浏览/下载:521/12  |  提交时间:2020/02/21