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ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1
作者:  Xie, Yusang;  Mei, Hong;  Wang, Wei;  Li, Xiao;  Hu, Pengfei
Adobe PDF(2481Kb)  |  收藏  |  浏览/下载:31/2  |  提交时间:2025/01/13
一种噻唑烷二酮类化合物、其药物组合物和其用途 专利
申请号:CN202410806451.8,申请日期: 2024-12-24,类型:发明申请,状态:公开
发明人:  范国平;  白芳;  许红涛;  祝献民;  王林
Adobe PDF(2056Kb)  |  收藏  |  浏览/下载:86/1  |  提交时间:2024/12/24
Design and synthesis of Thieno[3, 2-b]pyridinone derivatives exhibiting potent activities against Mycobacterium tuberculosis in vivo by targeting Enoyl-ACP reductase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 279
作者:  Liang, Lihong;  Liu, Zhiyong;  Chen, Jie;  Zha, Qin;  Zhou, Yihuan
Adobe PDF(1929Kb)  |  收藏  |  浏览/下载:197/2  |  提交时间:2024/09/30
High-temperature exposure during the early embryonic stage lowers core body temperature after growth via a hypothalamic Igfbp2-dependent mechanism 期刊论文
SCIENTIFIC REPORTS, 2024, 卷号: 14, 期号: 1
作者:  Yoshimura, Yuki;  Watanabe, Tatsuo;  Nakamura, Kazuomi;  Futatsugi, Akira;  Mikoshiba, Katsuhiko
Adobe PDF(4447Kb)  |  收藏  |  浏览/下载:91/2  |  提交时间:2024/12/23
MAI-TargetFisher: A proteome-wide drug target prediction method synergetically enhanced by artificial intelligence and physical modeling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024
作者:  Li, Shiwei;  Ren, Pengxuan;  Wang, Lin;  Han, Qilei;  Li, Fenglei
收藏  |  浏览/下载:129/0  |  提交时间:2024/12/02
A general temperature-guided language model to design proteins of enhanced stability and activity 期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 48
作者:  Jiang, Fan;  Li, Mingchen;  Dong, Jiajun;  Yu, Yuanxi;  Sun, Xinyu
Adobe PDF(2257Kb)  |  收藏  |  浏览/下载:70/1  |  提交时间:2024/12/27
Golgin45 assists mitosis via its nuclear localization sequence 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 735
作者:  Gao, Jingkai;  Zhu, Lianhui;  Yue, Xihua;  Jing, Shuaiyang;  Tang, Shuocheng
Adobe PDF(6239Kb)  |  收藏  |  浏览/下载:130/1  |  提交时间:2024/11/11
Astrocyte-specific secretome profiling reveals its correlation with neurological disorders 预印本
2024
作者:  Liu, Jie;  Gao, Jing;  Guo, Lin;  Ma, Guoming;  Guan, Mingfeng
Adobe PDF(7310Kb)  |  收藏  |  浏览/下载:46/9  |  提交时间:2025/01/06
Motif-guided Identification of KRAS-interacting Proteins 期刊论文
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1
作者:  Sanan, Wu;  Xiaoyang,Gao;  Di, Wu;  Lu, Liu;  Han, Yao
Adobe PDF(5705Kb)  |  收藏  |  浏览/下载:186/18  |  提交时间:2024/12/02
一种化合物及其在制备治疗肠道病毒相关疾病的药物中的应用 专利
申请号:CN202380028365.2,申请日期: 2024-11-08,类型:发明申请,状态:实质审查
发明人:  杨海涛;  周浩;  段胤凯;  王镐锋;  杨秀娜
Adobe PDF(1152Kb)  |  收藏  |  浏览/下载:166/2  |  提交时间:2024/11/08