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AI-driven high-throughput droplet screening of cell-free gene expression
期刊论文
NATURE COMMUNICATIONS, 2025
作者:
Zhu, Jiawei
;
Meng, Yaru
;
Gao, Wenli
;
Yang, Shuo
;
Zhu, Wenjie
Adobe PDF(2626Kb)
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浏览/下载:351/5
|
提交时间:2024/07/26
high-throughput screening
droplet microfluidics
cell-free gene expression
artificial intelligence
synthetic biology
A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
Adobe PDF(18107Kb)
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浏览/下载:76/2
|
提交时间:2025/02/12
Ablation
Biological organs
Chemotherapy
Gene expression
Gene therapy
Lung cancer
Mammals
Nanoparticles
Oligonucleotides
Transplantation (surgical)
Docetaxel
Endosomal escapes
Nano-devices
PH-responsive
Prodrug nanoparticle
Prodrugs
Receptor 1 small interference RNA
Receptor-1
Small interference RNA
Triple-negative breast cancers
Organ-specific gene expression control using DNA origami-based nanodevices
期刊论文
NANO LETTERS, 2024, 卷号: 24, 期号: 27, 页码: 8410–8417
作者:
Liu YX
;
Wang RX
;
Chen QMX
;
Chang Y
;
Chen Q
Adobe PDF(6648Kb)
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|
浏览/下载:334/30
|
提交时间:2024/06/23
DNA origami
LNP (lipid-based nanoparticle)
Cryo-EM
gene expression
mRNA
siRNA
Identification of key genes associated with persistent immune changes and secondary immune activation responses induced by influenza vaccination after COVID-19 recovery by machine learning methods
期刊论文
COMPUTERS IN BIOLOGY AND MEDICINE, 2024, 卷号: 169
作者:
Ren, Jingxin
;
Zhou, XianChao
;
Huang, Ke
;
Chen, Lei
;
Guo, Wei
Adobe PDF(8347Kb)
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收藏
|
浏览/下载:306/0
|
提交时间:2024/01/19
Blood
Chemical activation
Gene expression
Machine learning
Patient treatment
Recovery
Vaccines
Blood samples
COVID-19 recovery
Genes expression
Healthy controls
Immune activation
Immune change
Influenza vaccines
Machine learning methods
Machine-learning
Sample sets
scICML: Information-Theoretic Co-Clustering-Based Multi-View Learning for the Integrative Analysis of Single-Cell Multi-Omics Data
期刊论文
IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2024, 卷号: 21, 期号: 1, 页码: 200-207
作者:
Zeng, Pengcheng
;
Lin, Zhixiang
Adobe PDF(1032Kb)
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浏览/下载:286/44
|
提交时间:2024/03/08
Clustering
multi-view learning
single-cell multi-omics integration
Bioinformatics
Cytology
Data integration
Gene expression
Information analysis
Information theory
Pattern matching
'omics'
Clusterings
Genes expression
Genomics
Multi-view learning
Mutual informations
Optimisations
Pattern-matching
Single cells
Single-cell multi-omic integration
Identification and Expression Analysis of the Nucleotidyl Transferase Protein (NTP) Family in Soybean (
Glycine max
) under Various Abiotic Stresses
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 2
作者:
Kang, Liqing
;
Li, Changgen
;
Qin, Aokang
;
Liu, Zehui
;
Li, Xuanyue
Adobe PDF(4933Kb)
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浏览/下载:317/34
|
提交时间:2024/03/04
nucleotidyl transferase protein (NTP)
Glycine max
abiotic stress
RNA-seq
gene expression
subcellular localization
Expression profiles of east-west highly differentiated genes in Uyghur genomes
期刊论文
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 4
作者:
Ning, Zhilin
;
Tan, Xinjiang
;
Yuan, Yuan
;
Huang, Ke
;
Pan, Yuwen
Adobe PDF(1349Kb)
|
收藏
|
浏览/下载:369/64
|
提交时间:2023/05/29
gene expression
RNASeq
Xinjiang's Uyghurs
next-generation sequencing
A guidebook of spatial transcriptomic technologies, data resources and analysis approaches
期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2023, 卷号: 21, 页码: 940-955
作者:
Yue, Liangchen
;
Liu, Feng
;
Hu, Jiongsong
;
Yang, Pin
;
Wang, Yuxiang
Adobe PDF(5611Kb)
|
收藏
|
浏览/下载:269/0
|
提交时间:2023/03/17
Diagnosis
Disease control
Gene expression
Analysis approach
Cellular genes
Data resources
Disease diagnosis
Genes expression
Multicellular organisms
Single cells
Spatial transcriptomic technology
Technology data
Transcriptomics
TMELand: An end-to-end Pipeline for Quantification and Visualization of Waddingtons Epigenetic Landscape based on Gene Regulatory Network
期刊论文
IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2023, 卷号: PP, 期号: 99, 页码: 1-9
作者:
Lin Zhu
;
Xin Kang
;
Chunhe Li
;
Jie Zheng
Adobe PDF(4456Kb)
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收藏
|
浏览/下载:283/0
|
提交时间:2023/07/14
Boolean algebra
Cytology
Data visualization
Differential equations
Gene expression
Hopfield neural networks
Cell-fate
End to end
Epigenetics
Gene regulatory networks
ScRNA-seq data
State transition path
State transitions
Transition paths
Waddington epigenetic landscape
Bioinformatics study of the potential therapeutic effects of ginsenoside Rf in reversing nonalcoholic fatty liver disease
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 149
作者:
Chen, Lichun
;
Wang, Liziniu
;
Ao, Weizhen
;
Chen, Yu
;
Li, Songjian
Adobe PDF(17286Kb)
|
收藏
|
浏览/下载:324/2
|
提交时间:2022/05/27
NAFLD
Hepatic steatosis
Ginsenoside Rf
Molecular docking
Gene expression
Bioinformatics
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