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Bridging mechanical properties with atomic structures of polymorphic α-synuclein fibrils by single-molecule analysis and molecular dynamics simulations
期刊论文
AGGREGATE, 2025, 卷号: 6, 期号: 5
作者:
Bi, Lulu
;
Li, Linge
;
Li, Xiang
;
Wu, Shaojuan
;
Zhang, Xia
Adobe PDF(4227Kb)
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浏览/下载:136/7
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提交时间:2025/02/24
Crystal atomic structure
Molecular docking
Molecular dynamics
Neurodegenerative diseases
Dynamics simulation
Mechanical
Molecular simulations
Optical-
Parkinson's disease
Property
Single molecule
Single-molecule analysis
Α-syn fibril
α-synuclein
Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics
期刊论文
CIRCULATION, 2025, 卷号: 151, 期号: 17, 页码: 1248-1267
作者:
Han, Ximeng
;
Li, Yi
;
Wang, Enci
;
Zhu, Huan
;
Huang, Xiuzhen
收藏
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浏览/下载:18/0
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提交时间:2025/05/12
aortic diseases
developmental origin
lineage tracing
smooth muscle cell
TGF-beta
Amyloid-β Deposition Prediction with Large Language Model Driven and Task Oriented Learning of Brain Functional Networks
期刊论文
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2025, 卷号: 44, 期号: 4, 页码: 1809-1820
作者:
Yuxiao Liu
;
Mianxin Liu
;
Yuanwang Zhang
;
Yihui Guan
;
Qihao Guo
Adobe PDF(2838Kb)
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浏览/下载:174/5
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提交时间:2025/01/06
Functional neuroimaging
Neurodegenerative diseases
Neurophysiology
Positron emission tomography
Alzheimers disease
Brain networks
Convolutional networks
Emission tomography
Functional brain network
Functionals
Graph convolutional network
Language model
Large language model
Positron emission
Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer disease phenotypes in mouse models
期刊论文
NATURE BIOTECHNOLOGY, 2025
作者:
Feng, Xin
;
Jiang, Bo-Wen
;
Zhai, Si-Nan
;
Liu, Chu-Xiao
;
Wu, Hao
收藏
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浏览/下载:53/0
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提交时间:2025/04/11
Disease control
Neurodegenerative diseases
Neurons
Adeno-associated virus
Alzheimers disease
Disease phenotypes
Mice models
Neuroinflammation
Proinflammatory molecules
Protein kinase
RNA aptamer
Small-molecule inhibitors
Target proteins
Asynchronous Functional Brain Network Construction with Spatiotemporal Transformer for MCI Classification
期刊论文
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2025, 卷号: 44, 期号: 3, 页码: 1168-1180
作者:
Jianjia Zhang
;
Xiaotong Wu
;
Xiang Tang
;
Luping Zhou
;
Lei Wang
Adobe PDF(2613Kb)
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浏览/下载:190/1
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提交时间:2024/10/28
Brain mapping
Computer aided diagnosis
Computer aided network analysis
Neurodegenerative diseases
Alzheimers disease
Brain networks
Computer-aided
Functional brain network
Functional connectivity
Functionals
Region-of-interest
Regions of interest
Resting-state functional magnetic resonance imaging
Transformer
Identification of novel tau positron emission tomography tracers for chronic traumatic encephalopathy by comprehensive in silico screening and molecular dynamics simulation
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2025, 卷号: 27, 期号: 2, 页码: 754-767
作者:
Qi, Bote
;
Guan, Lulu
;
Tan, Jingwang
;
Li, Gengchen
;
Sun, Yunxiang
Adobe PDF(3086Kb)
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浏览/下载:105/1
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提交时间:2024/12/27
Binding energy
Computerized tomography
Germanium compounds
Neurodegenerative diseases
Neurophysiology
Photons
Positron emission tomography
Positrons
Binding affinities
Dynamics simulation
Emission tomography
Hydrogen bonding interactions
Hydrophobics
In-silico screening
Mild traumatic brain injuries
Neurodegenerative
Positron emission
Protofibrils
Silk-Based Self-Unfolding Electrode Array for Minimally-invasive Large-Scale Deep Brain Activity Monitoring
会议论文
2025 IEEE 38TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), Kaohsiung, Taiwan, 19-23 Jan. 2025
作者:
Jizhi Liang
;
Songtao Lai
;
Xiner Wang
收藏
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浏览/下载:36/0
|
提交时间:2025/03/25
Brain
Cerebrospinal fluid
Electrophysiology
Neurodegenerative diseases
Neurons
Scaffolds
Scaffolds (biology)
Deep-brain neural interface
Electrode arrays
Large-scales
Microelectrodes arrays
Minimally invasive
Neural interfaces
Parkinsonian sheep model
Sheep model
Silk-enabled self-unfolding
Unfoldings
Noninvasive Arterial Motion Monitoring with Aluminum Nitride-Based Piezoelectric Micromachined Ultrasonic Transducer
会议论文
2025 IEEE 38TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), Kaohsiung, Taiwan, 19-23 Jan. 2025
作者:
Yunhao Wang
;
Junxiang Cai
Adobe PDF(1137Kb)
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浏览/下载:37/2
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提交时间:2025/03/25
Cardiology
Diseases
Noninvasive medical procedures
Piezoelectric transducers
Ultrasonic applications
Ultrasonic sensors
Arterial motion
Arterial motion monitoring
Cardiovascular disease
Hot topics
Medical ultrasound systems
Micro-machined ultrasonic transducer
Piezoelectric
Piezoelectric micromachined ultrasonic transducer
Portable medical ultrasound system
Pulse echoes
A Coarse-to-Fine Framework for Mid-Radiotherapy Head and Neck Cancer MRI Segmentation
会议论文
LECTURE NOTES IN COMPUTER SCIENCE, Marrakesh, Morocco, October 17, 2024 - October 17, 2024
作者:
Ni, Jing
;
Yao, Qiulei
;
Liu, Yanfei
;
Qi, Haikun
Adobe PDF(1220Kb)
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收藏
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浏览/下载:8/1
|
提交时间:2025/05/30
Arthroplasty
Diseases
Magnetic resonance
Neuroimaging
Radiotherapy
3D segmentation
Adaptive radiation therapies
Coarse segmentation
Coarse to fine
Fine segmentations
Head-and-neck cancer
Magnetic resonance image
Prior information
Target volumes
Treatment modality
CIResDiff: A Clinically-Informed Residual Diffusion Model for Predicting Idiopathic Pulmonary Fibrosis Progression
会议论文
LECTURE NOTES IN COMPUTER SCIENCE (INCLUDING SUBSERIES LECTURE NOTES IN ARTIFICIAL INTELLIGENCE AND LECTURE NOTES IN BIOINFORMATICS), Marrakesh, Morocco, October 6, 2024 - October 6, 2024
作者:
Jiang, Caiwen
;
Xing, Xiaodan
;
Ou, Zaixin
;
Liu, Mianxin
;
Simon, Walsh
收藏
|
浏览/下载:239/0
|
提交时间:2024/11/29
Diagnosis
Patient treatment
Prediction models
Pulmonary diseases
Clinically informed
CLIP-based text processing
CT-scan
Diffusion model
Disease progression
Idiopathic pulmonary fibrosis
Prediction of pulmonary fibrose progression
Pulmonary fibrosis
Residual diffusion model
Text-processing
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