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A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
Adobe PDF(18107Kb)
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浏览/下载:76/2
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提交时间:2025/02/12
Ablation
Biological organs
Chemotherapy
Gene expression
Gene therapy
Lung cancer
Mammals
Nanoparticles
Oligonucleotides
Transplantation (surgical)
Docetaxel
Endosomal escapes
Nano-devices
PH-responsive
Prodrug nanoparticle
Prodrugs
Receptor 1 small interference RNA
Receptor-1
Small interference RNA
Triple-negative breast cancers
Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer
期刊论文
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1
作者:
Zhu, Binyu
;
Cai, Ying
;
Zhou, Lingli
;
Zhao, Lei
;
Chen, Jiameng
Adobe PDF(4666Kb)
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浏览/下载:57/2
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提交时间:2025/02/24
Interleukin 15-Presenting Nanovesicles with Doxorubicin-Loaded Ferritin Cores for Cancer Immunochemotherapy
期刊论文
ADVANCED SCIENCE, 2024
作者:
Zhai, Yihui
;
Zhang, Wen
;
Wang, Jinming
;
Kong, Ying
;
Rong, Rong
Adobe PDF(5190Kb)
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浏览/下载:161/3
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提交时间:2024/12/17
CTLs
IL15, immunotherapy
nanovesicles
NK cells
Cabozantinib-encapsulated and maytansine-conjugated high-density lipoprotein for immunotherapy in colorectal cancer
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 376, 页码: 138-148
作者:
Zheng, Chao
;
Jiang, Linyang
;
Gong, Xiang
;
Zhang, Wen
;
Pu, Rong
Adobe PDF(12782Kb)
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浏览/下载:245/4
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提交时间:2024/10/25
Synthetic high-density lipoprotein
Cabozantinib
Maytansine
Myeloid-derived suppressor cell
Immunosuppression
Colorectal cancer
Conformation Influences Biological Fates of Peptide-Based Nanofilaments by Modulating Protein Adsorption and Interfilament Entanglement
期刊论文
ADVANCED MATERIALS, 2024, 卷号: 37, 期号: 3
作者:
Cai, Ying
;
Xu, Tiantian
;
Zhu, Binyu
;
Chen, Junfan
;
Jiang, Linyang
Adobe PDF(11596Kb)
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浏览/下载:178/3
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提交时间:2024/12/17
drug delivery
nanofilaments
peptides
protein adsorptions
self-assembly
Enhancing immunotherapy efficacy against MHC-I deficient triple-negative breast cancer using LCL161-loaded macrophage membrane-decorated nanoparticles
期刊论文
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7
作者:
Zhang, Wen
;
Zhai, Yihui
;
Cai, Ying
;
Gong, Xiang
;
Jiang, Yunxuan
Adobe PDF(3490Kb)
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浏览/下载:257/2
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提交时间:2024/07/22
MHC-I deficiency
Macrophage
CD47
Immunotherapy
Triple-negative breast cancer
Phagocytosis
Immune checkpoint
Innate immunity
Chemical conjugation mitigates immunotoxicity of chemotherapy via reducing receptor-mediated drug leakage from lipid nanoparticles
期刊论文
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 23
作者:
Zheng, Chao
;
Zhang, Wen
;
Gong, Xiang
;
Xiong, Fengqin
;
Jiang, Linyang
Adobe PDF(7471Kb)
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浏览/下载:309/7
|
提交时间:2024/06/21
Diseases
Drug delivery
Lipoproteins
Liposomes
Mammals
Medical nanotechnology
Tumors
Cancer therapy
Drug leakage
High density lipoprotein
Immunotoxicity
Lipid nanoparticles
Low toxicity
Lymph node
Maytansine
Nanocarriers
Optimal design
Adenosine-modulating synthetic high-density lipoprotein for chemoimmunotherapy of triple-negative breast cancer
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 367, 页码: 637-648
作者:
Gong, Xiang
;
Zheng, Chao
;
Cai, Ying
;
Zhang, Wen
;
Zhu, Binyu
Adobe PDF(11207Kb)
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收藏
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浏览/下载:361/3
|
提交时间:2024/02/23
Cancer cells
Chemotherapy
Controlled drug delivery
Diseases
Lipoproteins
Mammals
Peptides
Phospholipids
Targeted drug delivery
Tumors
Adenosine
Cancer cells
Drug-conjugates
High density lipoprotein
Immunogenic cell death
Immunosuppression
Peptide drugs
Peptide-drug conjugate
Synthetic high-density lipoprotein
Triple-negative breast cancers
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
ADVANCED MATERIALS, 2024, 卷号: 36, 期号: 3
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
Adobe PDF(5155Kb)
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浏览/下载:285/2
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提交时间:2023/12/22
Cell death
Diseases
Endothelial cells
Ligands
Peptides
T-cells
Drug-conjugates
Endothelial-cells
Fas ligand
Immunotherapy
Integrin targeting
Peptide drugs
Peptide-drug conjugate
T lymphocytes
Triple-negative breast cancers
Tumor-associated endothelial cell
Histopathological auxiliary system for brain tumour (HAS-Bt) based on weakly supervised learning using a WHO CNS5-style pipeline
期刊论文
JOURNAL OF NEURO-ONCOLOGY, 2023
作者:
Ma, Yixin
;
Shi, Feng
;
Sun, Tianyang
;
Chen, Hong
;
Cheng, Haixia
Adobe PDF(3673Kb)
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收藏
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浏览/下载:529/141
|
提交时间:2023/05/29
Neuropathology
Histology
Deep learning
Multiply instance learning
Clinical practice
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