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Regulation of de novo and maintenance DNA methylation by DNA methyltransferases in post-implantation embryos
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 301, 期号: 1
作者:
Xu, Zhen
;
Shi, Jiajia
Adobe PDF(1280Kb)
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浏览/下载：199/10
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提交时间：2024/12/02
Cell culture
Gene encoding
Genome
Methylation
Stem cells
Bisulfite-sequencing
Control region
De novo methylation
DNA Methylation
DNMT1
DNMT3A
DNMT3B
Genomic imprinting
Implantation
Imprinting control region
Maintenance methylation
Whole-genome bisulphite sequencing
PPARγ and C/EBPα enable adipocyte differentiation upon inhibition of histone methyltransferase PRC2 in malignant tumors
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 10
作者:
Zhao, Jiaqi
;
Qian, Hui
;
An, Yang
;
Chu, Liping
;
Tan, Dongxia
Adobe PDF(8402Kb)
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浏览/下载：274/7
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提交时间：2024/11/08
Cell culture
Transcription
Adipocyte differentiation
C/EBPα sarcoma
Histone methyltransferases
Malignant tumors
Mesenchymal stem cell
Peroxisome proliferator-activated receptor
Polycomb
Polycomb repressive complex 2 inhibitor
PPARγ
Terminal differentiation
The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 5
作者:
Wu, Mengying
;
Hu, Liqiao
;
He, Lingli
;
Yuan, Liang
;
Yang, Lingling
Adobe PDF(2194Kb)
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浏览/下载：254/3
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提交时间：2024/05/11
Acylation
Cell signaling
Transcription
Transcription factors
Tumors
Coactivators
Crucial functions
Direct interactions
Direct links
Hippo pathway
Palmitoylation
Protein-protein interactions
Signalling pathways
TEAD4
Tumour suppressor
Structure and biochemical characterization of L-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of L-2-hydroxyglutaric aciduria
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 1
作者:
Yang, Jun
;
Chen, Xingchen
;
Jin, Shan
;
Ding, Jianping
Adobe PDF(3335Kb)
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浏览/下载：357/0
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提交时间：2024/01/19
Catalyst activity
Mitochondria
2-hydroxyglutaric aciduria
2-oxoglutarate
Biochemical characterization
Catalytic mechanisms
Drosophilla melanogaster
L-2-hydroxyglutarate dehydrogenase
Mitochondrial membranes
Protein crystallography
Structure characterization
Substrate specificity
Adenine base editor–mediated splicing remodeling activates noncanonical splice sites
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 12
作者:
Liu, Yuanyuan
;
Li, Qing
;
Yan, Tong
;
Chen, Haoran
;
Wang, Jiahua
Adobe PDF(2791Kb)
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浏览/下载：313/1
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提交时间：2023/12/22
Cell culture
Proteins
Acceptor sites
Adenine base editor
Dinucleotides
Editing tools
Enhanced GFP
Gene editing
Gene splicing
Noncanonical acceptor
Splice site
Splicing acceptor
PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 8
作者:
Song, Ziguo
;
Zhang, Guiquan
;
Huang, Shuhong
;
Liu, Yao
;
Li, Guanglei
Adobe PDF(1357Kb)
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浏览/下载：609/1
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提交时间：2023/07/28
Efficiency
Genes
Base editing
Gene inactivation
Nonsense mutation
Off-target
Prime editing
Prime editor-STOP
Start codons
Stop codons
Templated
Versatile tools
Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 6
作者:
Zhang, Yanchun
;
Xiong, Xuexue
;
Sun, Renhong
;
Zhu, Xiaotong
;
Wang, Chen
Adobe PDF(2978Kb)
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浏览/下载：370/6
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提交时间：2024/04/12
Amino acids
Cells
Diagnosis
Diseases
Enzymes
Tumors
Cell motility
Fps/fes related
Invasiveness
Ovarian cancer cells
Ovarian cancers
Ovarian carcinoma
Overexpressions
Protein degradation
Proteolysis-targeting chimera
Tyrosine kinase
Development of the non-receptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023
作者:
Yanchun Zhang
;
Xuexue Xiong
;
Renhong Sun
;
Xiaotong Zhu
;
Chen Wang
Adobe PDF(2707Kb)
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浏览/下载：320/4
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提交时间：2023/09/25
Protein degradation
PROTAC
Tyrosine kinase
FER
Ovarian cancer
An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 4
作者:
Huang, Ji
;
Liu, Xiangyang
;
Sun, Yadong
;
Li, Zhuang
;
Lin, Min-Han
Adobe PDF(1534Kb)
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浏览/下载：299/1
|
提交时间：2023/07/11
An A-Kinase Anchoring Protein (ACBD3) Coordinates Traffic-Induced PKA Activation At The Golgi
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 5
作者:
Jia, Jie
;
Tang, Shuocheng
;
Yue, Xihua
;
Jing, Shuaiyang
;
Zhu, Lianhui
Adobe PDF(23708Kb)
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收藏
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浏览/下载：324/1
|
提交时间：2023/04/24
Enzymes
A-kinase-anchoring proteins
Acyl-CoA
Acyl-CoA-binding domain-containing 3
Binding domain
Endoplasmic reticulum
Golgi
KDEL receptor
Membrane trafficking
Protein kinase A
Regulatory subunits
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