关键词云

成果统计

合作作者[TOP 5]

  • 刘志杰

    合作成果数:46

  • 武丽杰

    合作成果数:20

  • 吴屹然

    合作成果数:14

  • 赵素文

    合作成果数:13

  • 刘俊林

    合作成果数:12

访问统计


  总访问量
 3121

  访问来源
    内部: 16
    外部: 3105
    国内: 2763
    国外: 358

  年访问量
 401

  访问来源
    内部: 3
    外部: 398
    国内: 364
    国外: 37

  月访问量
 23

  访问来源
    内部: 0
    外部: 23
    国内: 13
    国外: 10

访问量

访问量

1. Crystal Structure of the Human Cannabinoid Receptor CB2 [5680]
2. Structure of the RNA-dependent RNA polymerase from COVID-19 virus [3278]
3. Crystal Structure of the Human Cannabinoid Receptor CB1 [2651]
4. Molecular insights into ligand recognition and G protein coupling .. [1757]
5. Crystal structures of agonist-bound human cannabinoid receptor CB1 [1478]
6. Organized cannabinoid receptor distribution in neurons revealed by.. [1461]
7. Structural insights into the activation initiation of full-length .. [1414]
8. Structural basis for strychnine activation of human bitter taste r.. [1397]
9. The unconventional activation of the muscarinic acetylcholine rece.. [1334]
10. Structural basis of CXC chemokine receptor 2 activation and signal.. [1112]
11. Functionality-Independent DNA Encoding of Complex Natural Products [1103]
12. Design and Synthesis of Novel GPR139 Agonists with Therapeutic Eff.. [1027]
13. MD Simulations Revealing Special Activation Mechanism of Cannabino.. [1007]
14. Structural insight into the constitutive activity of human orphan .. [907]
15. Novel Functionalized Cannabinoid Receptor Probes: Development of E.. [901]
16. Structural and Functional Insights into Cannabinoid Receptors [894]
17. The structural study of mutation-induced inactivation of human mus.. [885]
18. Activation and Signaling Mechanism Revealed by Cannabinoid Recepto.. [878]
19. Rational Remodeling of Atypical Scaffolds for the Design of Photos.. [874]
20. Structural basis of selective cannabinoid CB2 receptor activation [865]
21. Two-Dimensional Detergent Expansion Strategy for Membrane Protein .. [828]
22. Activation and allosteric modulation of muscarinic acetylcholine M.. [791]
23. Structural features of activated GPCR signaling complexes [764]
24. A Genetically Encoded F-19 NMR Probe Reveals the Allosteric Modula.. [742]
25. 一种基于喹诺酮结构的光控配体及其应用 [733]
26. Structural insights into the activation of chemokine receptor CXCR.. [727]
27. Carbon-silicon switch led to the discovery of novel synthetic cann.. [694]
28. Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a.. [689]
29. 一种噻吩并哒嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [677]
30. Unlocking TAS2R14 activation through intricate multi-ligand bindin.. [618]
31. 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用 [614]
32. 一种大麻素类化合物,其制备方法、组合物和用途 [613]
33. 人源大麻素受体CB2的晶体结构 [611]
34. 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [582]
35. Bitter taste TAS2R14 activation by intracellular tastants and chol.. [569]
36. 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用 [548]
37. 人源大麻素受体的结构生物学研究 [544]
38. 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [517]
39. 趋化因子受体的结构与信号转导机制 [505]
40. Structural basis of antagonist selectivity in endothelin receptors [488]
41. The chordata olfactory receptor database [474]
42. Structure basis of ligand recognition and activation of GPR55 [380]
43. Goods and Bads of the Endocannabinoid System as a Therapeutic Targ.. [346]
44. Cryo-EM structure of the human adenosine A2B receptor-Gs signaling.. [334]
45. Highly Selective Drug-Derived Fluorescent Probes for the Cannabino.. [330]
46. Structural insights into the high basal activity and inverse agoni.. [311]
47. Visualization of membrane localization and the functional state of.. [288]
48. Flipping the GPCR Switch: Structure-Based Development of Selective.. [278]
49. 稠杂环类化合物与其制备方法、药物组合物及应用 [257]
50. Cryo-EM structure of cannabinoid receptor CB1-β-arrestin complex [109]
51. Structural basis of stepwise proton sensing-mediated GPCR activati.. [105]
52. Structural basis of β-glucopyranosides salicin recognition by a h.. [103]
53. Structural basis of oligomerization-modulated activation and autoi.. [94]
54. STRUCTURAL AND FUNCTIONAL STUDIES ON BITTER TASTE RECEPTORS [62]
55. 吡咯并三嗪酮类化合物、包含其的药物组合物及其制备方法和用途 [20]

下载量

1. Crystal Structure of the Human Cannabinoid Receptor CB2 [1217]
2. Crystal Structure of the Human Cannabinoid Receptor CB1 [701]
3. Structure of the RNA-dependent RNA polymerase from COVID-19 virus [641]
4. Molecular insights into ligand recognition and G protein coupling .. [423]
5. Design and Synthesis of Novel GPR139 Agonists with Therapeutic Eff.. [373]
6. Organized cannabinoid receptor distribution in neurons revealed by.. [354]
7. The unconventional activation of the muscarinic acetylcholine rece.. [337]
8. Structural insights into the activation initiation of full-length .. [327]
9. Structural basis of selective cannabinoid CB2 receptor activation [227]
10. MD Simulations Revealing Special Activation Mechanism of Cannabino.. [199]
11. Unlocking TAS2R14 activation through intricate multi-ligand bindin.. [103]
12. Goods and Bads of the Endocannabinoid System as a Therapeutic Targ.. [61]
13. Bitter taste TAS2R14 activation by intracellular tastants and chol.. [26]
14. Functionality-Independent DNA Encoding of Complex Natural Products [21]
15. Structure basis of ligand recognition and activation of GPR55 [21]
16. Structural basis for strychnine activation of human bitter taste r.. [17]
17. Structural basis of antagonist selectivity in endothelin receptors [17]
18. The chordata olfactory receptor database [16]
19. Crystal structures of agonist-bound human cannabinoid receptor CB1 [15]
20. 一种噻吩并哒嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [14]
21. Structural insights into the high basal activity and inverse agoni.. [12]
22. Structural basis of oligomerization-modulated activation and autoi.. [11]
23. Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a.. [8]
24. Two-Dimensional Detergent Expansion Strategy for Membrane Protein .. [8]
25. Cryo-EM structure of cannabinoid receptor CB1-β-arrestin complex [8]
26. Structural basis of stepwise proton sensing-mediated GPCR activati.. [7]
27. Activation and allosteric modulation of muscarinic acetylcholine M.. [6]
28. Structural insight into the constitutive activity of human orphan .. [6]
29. 稠杂环类化合物与其制备方法、药物组合物及应用 [6]
30. Rational Remodeling of Atypical Scaffolds for the Design of Photos.. [4]
31. 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [4]
32. 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用 [4]
33. 一种大麻素类化合物,其制备方法、组合物和用途 [3]
34. 人源大麻素受体CB2的晶体结构 [3]
35. Visualization of membrane localization and the functional state of.. [3]
36. Structural basis of β-glucopyranosides salicin recognition by a h.. [3]
37. Structural and Functional Insights into Cannabinoid Receptors [2]
38. 一种基于喹诺酮结构的光控配体及其应用 [2]
39. Carbon-silicon switch led to the discovery of novel synthetic cann.. [2]
40. 趋化因子受体的结构与信号转导机制 [2]
41. STRUCTURAL AND FUNCTIONAL STUDIES ON BITTER TASTE RECEPTORS [2]
42. Activation and Signaling Mechanism Revealed by Cannabinoid Recepto.. [1]
43. The structural study of mutation-induced inactivation of human mus.. [1]
44. Structural basis of CXC chemokine receptor 2 activation and signal.. [1]
45. Structural features of activated GPCR signaling complexes [1]
46. Novel Functionalized Cannabinoid Receptor Probes: Development of E.. [1]
47. Structural insights into the activation of chemokine receptor CXCR.. [1]
48. 人源大麻素受体的结构生物学研究 [1]
49. 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用 [1]
50. 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用 [1]
51. Highly Selective Drug-Derived Fluorescent Probes for the Cannabino.. [1]
52. 吡咯并三嗪酮类化合物、包含其的药物组合物及其制备方法和用途 [1]