1.
Efficient generation of mouse models of human diseases via ABE- an..
[1584]
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2.
Efficient base editing in G/C-rich regions to model androgen insen..
[1384]
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3.
A Cas-embedding strategy for minimizing off-target effects of DNA ..
[1323]
|
4.
BE-PLUS: a new base editing tool with broadened editing window and..
[1298]
|
5.
Harnessing A3G for efficient and selective C-to-T conversion at C-..
[1172]
|
6.
Highly efficient and precise base editing by engineered dCas9-guid..
[1078]
|
7.
Developing ABEmax-NG with Precise Targeting and Expanded Editing S..
[1066]
|
8.
EasyCatch, a convenient, sensitive and specific CRISPR detection s..
[1037]
|
9.
Precise tumor immune rewiring via synthetic CRISPRa circuits gated..
[927]
|
10.
Enhancement of prime editing via xrRNA motif-joined pegRNA
[910]
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11.
Structure-guided engineering of adenine base editor with minimized..
[894]
|
12.
High-resolution annotation of the mouse preimplantation embryo tra..
[877]
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13.
Efficient Generation of Pathogenic A-to-G Mutations in Human Tripr..
[872]
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14.
Increasing the targeting scope and efficiency of base editing with..
[830]
|
15.
Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Meth..
[767]
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16.
Rapid and Sensitive Diagnosis of Drug-Resistant FLT3-F691L Mutatio..
[758]
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17.
Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base..
[679]
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18.
REPAIRx, a specific yet highly efficient programmable A > I RNA ba..
[673]
|
19.
Site-directed RNA editing (SDRE): Off-target effects and their cou..
[593]
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20.
Enhancing prime editing efficiency by modified pegRNA with RNA G-q..
[558]
|
21.
Efficient Gene Silencing by Adenine Base Editor-Mediated Start Cod..
[494]
|
22.
Deletion of ARGLU1 causes global defects in alternative splicing i..
[492]
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23.
PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM..
[478]
|
24.
Locus-specific DNA methylation of Mecp2 promoter leads to autism-l..
[467]
|
25.
CABE-RY: A PAM-flexible dual-mutation base editor for reliable mod..
[462]
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26.
Engineering an adenine base editor in human embryonic stem cells w..
[439]
|
27.
Comparison of gene disruption induced by cytosine base editing-med..
[415]
|
28.
Correction of the pathogenic mutation in TGM1 gene by adenine base..
[392]
|
29.
Broadening prime editing toolkits using RNA-Pol-II-driven engineer..
[369]
|
30.
Epigenetic editing alleviates Angelman syndrome phenotype in mice ..
[315]
|
31.
融合蛋白及其在碱基编辑中的用途
[314]
|
32.
一种融合蛋白及其在碱基编辑中的用途
[299]
|
33.
Modeling a cataract disorder in mice with prime editing
[289]
|
34.
Engineering of near-PAMless adenine base editor with enhanced edit..
[289]
|
35.
Modes of genetic adaptations underlying functional innovations in ..
[268]
|
36.
Base Editing Tool And Use Thereof
[266]
|
37.
Base editing-mediated perturbation of endogenous PKM1/2 splicing f..
[252]
|
38.
利用三代测序技术识别小鼠早期胚胎等位基因特异的转录本和剪切事件
[193]
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39.
开发利用碱基编辑器和先导编辑器调控RNA剪接并研究其在小鼠早期胚胎发..
[90]
|
40.
Viral N protein hijacks deaminase-containing RNA granules to enhan..
[81]
|