Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui

doi:10.1016/j.scr.2021.102645

	Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui
	Zhang, Yi 1,2,3,4; Shou, Jiajun 1,2,3,4; Gu, Wentao 1,2,3,4; Di, Weihao5,6,7,8 ; Zhao, Jian5,6,7,8 ; Wang, Ying5,6,7,8 ; Gu, Shixin 1,2,3,4
	2022-04
发表期刊	STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year])
ISSN	1873-5061
EISSN	1876-7753
卷号	60
发表状态	已发表
DOI	10.1016/j.scr.2021.102645
摘要	With the development of cytology, the establishment of cell models in vitro has become a powerful means to study the mechanism and treatment of diseases. Here we successfully generated the IPSC-derived modeling system of a 25-year-old healthy male. His peripheral blood mononuclear cells (PBMC) were reprogrammed using human OKSM (SOX2, OCT3/4, KLF4, and C-MYC) transcription factors using a non-integrated additional vector system. Immunocytochemistry demonstrated that IPSCS expressed all the markers of pluripotency and demonstrated their ability to differentiate spontaneously from three hypoderms in vitro. Karyotype is normal.
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收录类别	SCIE ; SCI
语种	英语
资助项目	national natural science foundation of China[81870970]
WOS研究方向	Cell Biology ; Biotechnology & Applied Microbiology
WOS类目	Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology
WOS记录号	WOS:000788511600006
出版者	ELSEVIER
Scopus 记录号	2-s2.0-85123576386
来源库	Scopus
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/153585
专题	生命科学与技术学院_博士生免疫化学研究所_PI研究组_赵简组
通讯作者	Wang, Ying; Gu, Shixin
作者单位	1.Fudan Univ, Huashan Hosp, Shanghai Med Coll, Dept Neurosurg, Shanghai, Peoples R China 2.Shanghai Clin Med Ctr Neurosurg, Shanghai, Peoples R China 3.Fudan Univ, Neurosurg Inst, Shanghai, Peoples R China 4.Shanghai Key Lab Brain Funct & Restorat & Neural, Shanghai, Peoples R China 5.ShanghaiTech Univ, Lab Regenerat Med & Neural Repair, Shanghai 201210, Peoples R China 6.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China 7.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 8.Shanghai Clin Res & Trial Ctr, Shanghai 201210, Peoples R China
通讯作者单位	上海科技大学; 免疫化学研究所; 生命科学与技术学院
推荐引用方式 GB/T 7714	Zhang, Yi,Shou, Jiajun,Gu, Wentao,et al. Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui[J]. STEM CELL RESEARCH,2022,60.
APA	Zhang, Yi.,Shou, Jiajun.,Gu, Wentao.,Di, Weihao.,Zhao, Jian.,...&Gu, Shixin.(2022).Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui.STEM CELL RESEARCH,60.
MLA	Zhang, Yi,et al."Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui".STEM CELL RESEARCH 60(2022).