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Site-selective Csp(3)-H aryloxylation of natural product Tanshinone IIA and its analogues | |
2017-05-10 | |
发表期刊 | TETRAHEDRON LETTERS (IF:1.5[JCR-2023],1.6[5-Year]) |
ISSN | 0040-4039 |
卷号 | 58期号:19页码:1822-1825 |
发表状态 | 已发表 |
DOI | 10.1016/j.tetlet.2017.03.078 |
摘要 | A novel catalyst-free Csp(3)-H aryloxylation approach allowing for rapid installation of a wide range of aryloxyl groups regioselectively at the C-4 position of Tanshinone IIA under simple and mild conditions was developed. This unique protocol exhibited atom-/step-economy, low cost, high efficiency and robust functional-group tolerance, which will greatly facilitate to diversify the A-ring of the bioactive natural product. (C) 2017 Elsevier Ltd. All rights reserved. |
关键词 | Natural product Tanshinone IIA Chemical modification Aryloxylation C-H activation |
收录类别 | SCI ; IC ; CCR |
语种 | 英语 |
资助项目 | "Personalized Medicines Molecular Signature-based Drug Discovery and Development", Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020320] |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Organic |
WOS记录号 | WOS:000401204400004 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS关键词 | SALVIA-MILTIORRHIZA BUNGE ; VASODILATIVE ACTIVITY ; OXIDATIVE STRESS ; DERIVATIVES ; ABSORPTION ; ACTIVATION ; EXPRESSION |
原始文献类型 | Article |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/1374 |
专题 | 生命科学与技术学院 生命科学与技术学院_特聘教授组_张翱组 生命科学与技术学院_博士生 |
通讯作者 | Ding, Chunyong |
作者单位 | 1.Univ Sci & Technol China, Nano Sci & Technol Inst, Suzhou 215123, Peoples R China 2.ShanghaiTech Univ, Shanghai 20120, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res Synthet Organ & Med Chem, Shanghai 201203, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Liang, Bing,Yu, Shujuan,Li, Jie,et al. Site-selective Csp(3)-H aryloxylation of natural product Tanshinone IIA and its analogues[J]. TETRAHEDRON LETTERS,2017,58(19):1822-1825. |
APA | Liang, Bing.,Yu, Shujuan.,Li, Jie.,Wang, Fan.,Liang, Gaolin.,...&Ding, Chunyong.(2017).Site-selective Csp(3)-H aryloxylation of natural product Tanshinone IIA and its analogues.TETRAHEDRON LETTERS,58(19),1822-1825. |
MLA | Liang, Bing,et al."Site-selective Csp(3)-H aryloxylation of natural product Tanshinone IIA and its analogues".TETRAHEDRON LETTERS 58.19(2017):1822-1825. |
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