上海科技大学知识管理系统

本公开涉及式(I)的基于戊二酰亚胺骨架的化合物或其盐、对映异构体、立体异构体、溶剂化物、多晶型物及其应用。本公开还涉及包含作为活性成分的式(I)的基于戊二酰亚胺骨架的化合物或其盐、对映异构体、立体异构体、溶剂化物、多晶型物的药物组合物及其应用。本公开设计合成的一系列化合物能有效地预防和//或治疗肿瘤。。

The present disclosure relates to glutarimide skeleton-based compounds of formula (I) or salts, enantiomers, stereoisomers, solvates, polymorphs thereof and uses thereof. The present disclosure also relates to pharmaceutical compositions comprising, as active ingredient, a glutarimide skeleton-based compound of formula (I) or a salt, enantiomer, stereoisomer, solvate, polymorph thereof and uses thereof. A series of compounds designed and synthesized by the invention can effectively prevent and//or treat tumors. .