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Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background
2021-05
发表期刊STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year])
ISSN1873-5061
卷号53
发表状态已发表
DOI10.1016/j.scr.2021.102314
摘要

A healthy 31-year-old Chinese Han female donated peripheral blood mononuclear cells (PBMC). Her PBMCs were reprogrammed with human OKSM (OCT3/4, KLF4 SOX2, and c-MYC) transcription factors by the non-integrating episomal vector system. Immunocytochemistry for pluripotency markers confirmed the pluripotency of transgene-free iPSCs. Their ability to differentiate spontaneously three germ layers in vitro is also confirmed. The iPSC line displayed a normal karyotype. This model can be used as a control in pathological mechanism studies.

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收录类别SCI ; SCIE
语种英语
WOS研究方向Cell Biology ; Biotechnology & Applied Microbiology
WOS类目Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology
WOS记录号WOS:000663438300009
出版者ELSEVIER
原始文献类型Article
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文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/126982
专题生命科学与技术学院_硕士生
共同第一作者Di,Weihao; Zhang,Bei
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Dai,Qiuting,Di,Weihao,Zhang,Yi,et al. Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background[J]. STEM CELL RESEARCH,2021,53.
APA Dai,Qiuting.,Di,Weihao.,Zhang,Yi.,Gu,Shixin.,Zhao,Jian.,...&Wang,Ying.(2021).Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background.STEM CELL RESEARCH,53.
MLA Dai,Qiuting,et al."Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background".STEM CELL RESEARCH 53(2021).
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