Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration

doi:10.1186/s13287-015-0207-x

	Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration
	Qu, Zepeng 1; Guan, Yuan 1; Cui, Lu 1; Song, Jian5 ; Gu, Junjie 4; Zhao, Hanzhi 4; Xu, Lei 6,7; Lu, Lixia 2,3,6,7; Jin, Ying1,4,5 ; Xu, Guo-Tong 2,3,6,7
	2015-11-09
发表期刊	STEM CELL RESEARCH & THERAPY
ISSN	1757-6512
卷号	6
发表状态	已发表
DOI	10.1186/s13287-015-0207-x
摘要	Introduction: Degenerative retinal diseases like age-related macular degeneration (AMD) are the leading cause of blindness. Cell transplantation showed promising therapeutic effect for such diseases, and embryonic stem cell (ESC) is one of the sources of such donor cells. Here, we aimed to generate retinal progenitor cells (RPCs) from rat ESCs (rESCs) and to test their therapeutic effects in rat model.
关键词	Rat embryonic stem cell Degenerative retinal diseases Retinal progenitor cell (RPC) Transplantation Royal College of Surgeons (RCS) rat
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[31171419]
WOS研究方向	Cell Biology ; Research & Experimental Medicine
WOS类目	Cell & Tissue Engineering ; Cell Biology ; Medicine, Research & Experimental
WOS记录号	WOS:000364284700001
出版者	BMC
WOS关键词	IN-VITRO DIFFERENTIATION ; HUMAN NEURAL PROGENITORS ; LONG-TERM PRESERVATION ; ERG B-WAVE ; RCS RATS ; MACULAR DEGENERATION ; RETINITIS-PIGMENTOSA ; VISUAL FUNCTION ; PHOTORECEPTOR PRECURSORS ; CORTICAL TISSUES
原始文献类型	Article
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/2093
专题	生命科学与技术学院生命科学与技术学院_特聘教授组_金颖组生命科学与技术学院_硕士生
通讯作者	Jin, Ying
作者单位	1.Shanghai Jiao Tong Univ, Sch Med, Lab Mol Dev Biol, Shanghai 200025, Peoples R China 2.Shanghai Tenth Peoples Hosp, Dept Ophthalmol, Shanghai 200092, Peoples R China 3.Tongji Univ, Sch Med, Lab Clin Visual Sci, Tongji Eye Inst, Shanghai 200092, Peoples R China 4.Shanghai Jiao Tong Univ, Chinese Acad Sci, Key Lab Stem Cell Biol, Inst Hlth Sci,Shanghai Inst Biol Sci,Sch Med, Shanghai 200031, Peoples R China 5.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 6.Tongji Univ, Sch Med, Stem Cell Res Ctr, Dept Regenerat Med, Shanghai 200092, Peoples R China 7.Tongji Univ, Sch Med, Inst Nutr Sci, Shanghai 200092, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Qu, Zepeng,Guan, Yuan,Cui, Lu,et al. Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration[J]. STEM CELL RESEARCH & THERAPY,2015,6.
APA	Qu, Zepeng.,Guan, Yuan.,Cui, Lu.,Song, Jian.,Gu, Junjie.,...&Xu, Guo-Tong.(2015).Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration.STEM CELL RESEARCH & THERAPY,6.
MLA	Qu, Zepeng,et al."Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration".STEM CELL RESEARCH & THERAPY 6(2015).