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成果统计

合作作者[TOP 5]

  • Gu, Junjie

    合作成果数：6

  • Tang, Fan

    合作成果数：5

  • Fang, Zhuoqing

    合作成果数：4

  • Li, Chunliang

    合作成果数：3

  • Liao, Bing

    合作成果数：3
金颖 其他
所在学院： 生命科学与技术学院
职务： --
研究方向： 多能干细胞和胚胎早期发育分子调控机制（中科院上海生命科学研究院健康科学研究所研究员）
备注： --
金颖

研究内容

揭示多能干细胞（包括胚胎干细胞、iPS细胞和哺乳类动物发育早期细胞）自我更新和发育全能性的分子机制。采取的主要策略是通过对已知参与多能干细胞特性调控的重要信号通路及细胞内因子作用机制的研究结合全基因组的表达谱式和功能筛选，揭示多能干细胞维持自我更新与定向分化之间转化的分子基础。同时，建立各种多能干细胞系，并探索多能干细胞定向神经分化的调控机制。这些研究将有助于多能干细胞的体外扩增、定向分化和临床应用。

科研成果

10 4873 1123 465 0 7
Items Views Downloads TC[WOS] TC[CSCD] H-index
排序方式：
 [1] Liu, Xinyuan.,Fang, Zhuoqing.,Wen, Jing.,Tang, Fan.,Liao, Bing.,...&Jin, Ying.(2020).SOX1 Is Required for the Specification of Rostral Hindbrain Neural Progenitor Cells from Human Embryonic Stem Cells.ISCIENCE,23(9).浏览/下载:362/0; 被引[WOS]:6; IF:4.6/5.0评论推荐收藏
 [2] Fang, Zhuoqing.,Liu, Xinyuan.,Wen, Jing.,Tang, Fan.,Zhou, Yang.,...&Jin, Ying.(2019).SOX21 Ensures Rostral Forebrain Identity by Suppression of WNT8B during Neural Regionalization of Human Embryonic Stem Cells.STEM CELL REPORTS,13(6),1038-1052.浏览/下载:1034/352; 被引[WOS]:14; IF:5.9/5.9评论推荐收藏
 [3] Ding, Jianyi.,Fang, Zhuoqing.,Liu, Xinyuan.,Zhu, Zhexin.,Wen, Chunsheng.,...&Jin, Ying.(2019).CDK11 safeguards the identity of human embryonic stem cells via fine-tuning signaling pathways.JOURNAL OF CELLULAR PHYSIOLOGY.浏览/下载:450/12; 被引[WOS]:2; IF:4.5/5.3评论推荐收藏
 [4] Hu, Jing.,Li, Shuang.,Sun, Xiaozhi.,Fang, Zhuoqing.,Wang, Lina.,...&Jin, Ying.(2019).Stk40 deletion elevates c-JUN protein level and impairs mesoderm differentiation.JOURNAL OF BIOLOGICAL CHEMISTRY,294(25),9959-9972.浏览/下载:474/0; 被引[WOS]:7; IF:4.0/4.4评论推荐收藏
 [5] Qu, Zepeng.,Guan, Yuan.,Cui, Lu.,Song, Jian.,Gu, Junjie.,...&Xu, Guo-Tong.(2015).Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration.STEM CELL RESEARCH & THERAPY,6.浏览/下载:1362/423; 被引[WOS]:20; IF:7.1/7.9评论推荐收藏
 [6] Zhang, Hui.,Ma, Yu.,Gu, Junjie.,Liao, Bing.,Li, Jiwen.,...&Jin, Ying.(2012).Reprogramming of somatic cells via TAT-mediated protein transduction of recombinant factors.BIOMATERIALS,33(20),5047-5055.浏览/下载:95/0; 被引[WOS]:62; IF:12.8/13.1评论推荐收藏
 [7] Li, Xiang.,Zhu, Lili.,Yang, Acong.,Lin, Jiangwei.,Tang, Fan.,...&Jin, Ying.(2011).Calcineurin-NFAT Signaling Critically Regulates Early Lineage Specification in Mouse Embryonic Stem Cells and Embryos.CELL STEM CELL,8(1),46-58.浏览/下载:109/0; 被引[WOS]:87; IF:19.8/22.6评论推荐收藏
 [8] Fang, Hai.,Yang, Ying.,Li, Chunliang.,Fu, Shijun.,Yang, Zuqing.,...&Jin, Ying.(2010).Transcriptome Analysis of Early Organogenesis in Human Embryos.DEVELOPMENTAL CELL,19(1),174-184.浏览/下载:79/0; 被引[WOS]:58; IF:10.7/11.5评论推荐收藏
 [9] Li, Lingjie.,Sun, Lei.,Gao, Furong.,Jiang, Jing.,Yang, Ying.,...&Jin, Ying.(2010).Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,107(4),1402-1407.浏览/下载:458/193; 被引[WOS]:62; IF:9.4/10.8评论推荐收藏
 [10] Li, Chunliang.,Zhou, Junmei.,Shi, Guilai.,Ma, Yu.,Yang, Ying.,...&Jin, Ying.(2009).Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells.HUMAN MOLECULAR GENETICS,18(22),4340-4349.浏览/下载:450/143; 被引[WOS]:147; IF:3.1/4.2评论推荐收藏