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Bridging mechanical properties with atomic structures of polymorphic α-synuclein fibrils by single-molecule analysis and molecular dynamics simulations 期刊论文
AGGREGATE, 2025, 卷号: 6, 页码: e70023
作者:  Bi, Lulu;  Li, Linge;  Li, Xiang;  Wu, Shaojuan;  Zhang, Xia
Adobe PDF(4227Kb)  |  收藏  |  浏览/下载：96/5  |  提交时间：2025/02/24
RPA transforms RNase H1 to a bidirectional exonuclease for efficient RNA–DNA hybrid cleavage 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 页码: 7464
作者:  Li, Yanan;  Liu, Chao;  Jia, Xinshuo;  Bi, Lulu;  Ren, Zhiyun
Adobe PDF(4386Kb)  |  收藏  |  浏览/下载：348/16  |  提交时间：2024/08/29
Phase-separated ParB enforces diverse DNA compaction modes and stabilizes the parS-centered partition complex 期刊论文
NUCLEIC ACIDS RESEARCH, 2024, 卷号: 52, 页码: 8385-8398
作者:  Zhao, Yilin;  Guo, Lijuan;  Hu, Jiaojiao;  Ren, Zhiyun;  Li, Yanan
Adobe PDF(2133Kb)  |  收藏  |  浏览/下载：459/86  |  提交时间：2024/06/24
Joint efforts of replicative helicase and SSB ensure inherent replicative tolerance of G-quadruplex 期刊论文
ADVANCED SCIENCE, 2023, 卷号: 11, 期号: 9, 页码: 2307696
作者:  Guo, Lijuan;  Bao, Yanling;  Zhao, Yilin;  Ren, Zhiyun;  Bi, Lulu
Adobe PDF(7682Kb)  |  收藏  |  浏览/下载：370/8  |  提交时间：2023/12/18
Enlarged DNA unwinding by Nme2Cas9 permits a broadened base editing window beyond the protospacer 期刊论文
SCIENCE CHINA LIFE SCIENCES, 2023, 卷号: 67, 页码: 424-427
作者:  Chen, Ziting;  Li, Xiangyang;  Zhang, Qian;  Sun, Wenjun;  Song, Xiaoxuan
Adobe PDF(892Kb)  |  收藏  |  浏览/下载：434/11  |  提交时间：2023/08/11
Discrete RNA–DNA hybrid cleavage by the EXD2 exonuclease pinpoints two rate-limiting steps 期刊论文
THE EMBO JOURNAL, 2023, 卷号: 42, 页码: e111703
作者:  Jia, Xinshuo;  Li, Yanan;  Wang, Teng;  Bi, Lulu;  Guo, Lijuan
Adobe PDF(2383Kb)  |  收藏  |  浏览/下载：541/8  |  提交时间：2022/11/06
Bloom syndrome helicase compresses single-stranded DNA into phase-separated condensates 期刊论文
ANGEWANDTE CHEMIE INTERNATIONAL EDITION, 2022, 卷号: 61, 页码: e202209463
作者:  Wang, Teng;  Hu, Jiaojiao;  Li, Yanan;  Bi, Lulu;  Guo, Lijuan
Adobe PDF(7496Kb)  |  收藏  |  浏览/下载：318/1  |  提交时间：2022/08/26
Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis 期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 16, 页码: 9294-9305
作者:  Guo, Lijuan;  Zhao, Yilin;  Zhang, Qian;  Feng, Ying;  Bi, Lulu
Adobe PDF(4955Kb)  |  收藏  |  浏览/下载：879/259  |  提交时间：2022/08/15
The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 23, 页码: e2116462119
作者:  Bi, Lulu;  Qin, Zhenheng;  Wang, Teng;  Li, Yanan;  Jia, Xinshuo
Adobe PDF(1844Kb)  |  收藏  |  浏览/下载：498/3  |  提交时间：2022/06/20
Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer 期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: 21, 页码: 12433-12444
作者:  Zhang, Qian;  Chen, Ziting;  Wang, Fangzhu;  Zhang, Siqi;  Chen, Hongyu
Adobe PDF(4976Kb)  |  收藏  |  浏览/下载：389/2  |  提交时间：2021/12/13
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