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Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
Adobe PDF(7984Kb)
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浏览/下载:178/3
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提交时间:2024/12/30
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
DNFE: Directed-network flow entropy for detecting the tipping points during biological processes
预印本
2024
作者:
Peng, Xueqing
;
Li, Peiluan
;
Luonan, Chen
收藏
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浏览/下载:206/0
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提交时间:2024/10/08
directed network
scRNA-seq
critical states
dynamic network biomarker
transcription factor
Gramine protects against pressure overload-induced pathological cardiac hypertrophy through Runx1-TGFBR1 signaling
期刊论文
PHYTOMEDICINE, 2023, 卷号: 114
作者:
Xu, Longwei
;
Su, Yuanyuan
;
Yang, Xiaolin
;
Bai, Xueyang
;
Wang, Yu
Adobe PDF(16432Kb)
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浏览/下载:323/0
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提交时间:2023/05/15
Cardiac hypertrophy
Gramine
Transforming growth factor beta signaling
Runt-related transcription factor 1
Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment
期刊论文
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 4
作者:
Tang, Shijie
;
Xue, Yun
;
Qin, Zhen
;
Fang, Zhaoyuan
;
Sun, Yihua
Adobe PDF(12565Kb)
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浏览/下载:671/184
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提交时间:2023/06/09
Biological organs
Diagnosis
Genome
Transcription
Tumors
ALK fusion
Counteracting transcription factor regulatory network
CXCL3/CXCL5
Genomics
LSD1
LUAS
Microenvironments
Regulatory network
Transcriptomics
Transdifferentiation
Current and future: Targeted therapy for RUNX1-mutated acute myeloid leukemia
会议论文
PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, Virtual, Online, United kingdom, September 2, 2023 - September 9, 2023
作者:
Jiang, Zhaoyang
Adobe PDF(146Kb)
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浏览/下载:187/0
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提交时间:2024/02/23
Blood
Diagnosis
Diseases
Patient treatment
'current
Acute myeloid leukemia
Bone marrow
Clinical study
Malignant tumors
Runt related transcription factor
RUNX1-related cytotherapy
Survival rate
Targeted therapy
Tissue development
FindIT2: an R/Bioconductor package to identify influential transcription factor and targets based on multi-omics data
期刊论文
BMC GENOMICS, 2022, 卷号: 23
作者:
Shang, Guan Dong
;
Xu, Zhou Geng
;
Wan, Mu Chun
;
Wang, Fu Xiang
;
Wang, Jia Wei
Adobe PDF(2884Kb)
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浏览/下载:411/111
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提交时间:2022/05/05
ATAC-seq
ChIP-seq
Chromatin accessibility
Gene regulation
R package
Transcription factor
Identification of key transcription factors associated with cerebral ischemia-reperfusion injury based on gene-set enrichment analysis
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: 43, 期号: 6, 页码: 2429-2439
作者:
Adobe PDF(1495Kb)
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浏览/下载:1215/402
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提交时间:2019/06/04
ischemic stroke
cerebral ischemia-reperfusion injury
transcription factor
gene-set enrichment analysis
functional pathway enrichment
Distinct Proteome Remodeling of Industrial Saccharomyces cerevisiae in Response to Prolonged Thermal Stress or Transient Heat Shock
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1812-1825
作者:
Xiao, Weidi
;
Duan, Xiaoxiao
;
Lin, Yuping
;
Cao, Qichen
;
Li, Shanshan
Adobe PDF(5074Kb)
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浏览/下载:574/7
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提交时间:2018/06/13
industrial yeast
thermotolerance
heat shock response
transcription factor
DIA
SWATH
TGF-beta signaling pathway in early mouse development and embryonic stem cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 1, 页码: 68-73
作者:
Liu, Chang
;
Peng, Guangdun
;
Jing, Naihe
Adobe PDF(328Kb)
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浏览/下载:1052/332
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提交时间:2018/03/01
TGF-beta
mouse embryo
embryonic stem cells
Smad
transcription factor
chromatin modification
Local network component analysis for quantifying transcription factor activities
期刊论文
METHODS, 2017, 卷号: 124, 页码: 25-35
作者:
Shi, Qianqian
;
Zhang, Chuanchao
;
Guo, Weifeng
;
Zeng, Tao
;
Lu, Lina
Adobe PDF(2169Kb)
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浏览/下载:507/0
|
提交时间:2017/08/26
Network component analysis
Integrative analysis
Data heterogeneity
Transcription factor activities
Adaptive optimization strategy
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