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Drug discovery targeting thyroid hormone receptor f3 (THRf3) for the treatment of liver diseases and other medical indications 期刊论文
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1
作者:  Wang, Kean;  Chen, Feiyang;  Wang, Jiang;  Liu, Hong
Adobe PDF(2638Kb)  |  收藏  |  浏览/下载：76/2  |  提交时间：2025/03/03
Structural basis for activation of somatostatin receptor 5 by cyclic neuropeptide agonists 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 26
作者:  Li, Jingru;  You, Chongzhao;  Li, Yang;  Li, Changyao;  Fan, Wenjia
Adobe PDF(9327Kb)  |  收藏  |  浏览/下载：256/4  |  提交时间：2024/07/08
Selection of Leptin Surrogates by a General Phenotypic Screening Method for Receptor Agonists 期刊论文
BIOMOLECULES, 2024, 卷号: 14, 期号: 4
作者:  Wang T(王涛);  Xixi Chen;  Guang Yang;  Xiaojie Shi
Adobe PDF(1762Kb)  |  收藏  |  浏览/下载：517/58  |  提交时间：2024/04/28
Structural optimizations and bioevaluation of N-H aporphine analogues as Gq-biased and selective serotonin 5-HT2C receptor agonists 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 123
作者:  Mao, Qi;  Zhang, Bingjie;  Tian, Sheng;  Qin, Wangzhi;  Chen, Jiaojiao
Adobe PDF(3797Kb)  |  收藏  |  浏览/下载：279/2  |  提交时间：2022/11/08
Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors 预印本
2021
作者:  Zhao, Fenghui;  Zhou, Qingtong;  Cong, Zhaotong;  Hang, Kaini;  Zou, Xinyu
Adobe PDF(20536Kb)  |  收藏  |  浏览/下载：306/0  |  提交时间：2024/01/09
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110
作者:  Lin, Lin
Adobe PDF(4286Kb)  |  收藏  |  浏览/下载：233/0  |  提交时间：2021/07/23
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.
Adobe PDF(2565Kb)  |  收藏  |  浏览/下载：296/0  |  提交时间：2022/12/09
Identification of Novel 1-O-Substituted Aporphine Analogues as Potent 5-HT2C Receptor Agonists 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 549-559
作者:  Mao, Qi;  Zhang, Bingjie;  Li, Wanwan;  Tian, Sheng;  Shui, Wenqing
Adobe PDF(2903Kb)  |  收藏  |  浏览/下载：354/2  |  提交时间：2020/03/16
Design of fluorinated cyclopropane derivatives of 2-phenylcyclopropylmethylamine leading to identification of a selective serotonin 2C (5-HT2C) receptor agonist without 5-HT2B agonism 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182
作者:  Zhang, Guiping;  McCorvy, John D.;  Shen, Sida;  Cheng, Jianjun;  Roth, Bryan L.
Adobe PDF(1237Kb)  |  收藏  |  浏览/下载：401/10  |  提交时间：2019/12/19
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