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Recent advances in targeted degradation in the RAS pathway 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6
作者:  Ge, Zhiming;  Fan, Zisheng;  He, Wei;  Zhou, Guizhen;  Zhou, Yidi
Adobe PDF(2827Kb)  |  收藏  |  浏览/下载：29/2  |  提交时间：2025/03/25
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1
作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei
Adobe PDF(14589Kb)  |  收藏  |  浏览/下载：80/3  |  提交时间：2025/03/03
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3- d ]pyrimidin-7-one-based SOS1 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107
作者:  Wang, Kun;  Zhou, Zehui;  Ma, Xinyi;  Xu, Jiahang;  Xu, Wangyang
Adobe PDF(1940Kb)  |  收藏  |  浏览/下载：244/2  |  提交时间：2024/06/17
Identification and characterization of Sofosbuvir-resistant mutations of hepatitis C virus genotype 3a replicon 期刊论文
JOURNAL OF MEDICAL VIROLOGY, 2023, 卷号: 95, 期号: 12
作者:  Ngari, Jackline Wangu;  Leumi, Steve;  Han, Lin;  Liu, Chaolun;  Tong, Yimin
Adobe PDF(3576Kb)  |  收藏  |  浏览/下载：226/0  |  提交时间：2024/03/03
Effect on cell survival and cytoophidium assembly of the adRP-10-related IMPDH1 missense mutation Asp226Asn 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2023, 卷号: 11
作者:  Keppeke, Gerson Dierley;  Chang, Chia-Chun;  Zhang, Ziheng;  Liu, Ji-Long
Adobe PDF(5111Kb)  |  收藏  |  浏览/下载：559/101  |  提交时间：2023/10/16
PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 8
作者:  Song, Ziguo;  Zhang, Guiquan;  Huang, Shuhong;  Liu, Yao;  Li, Guanglei
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载：624/1  |  提交时间：2023/07/28
Effects of novel variants in BMP15 gene on litter size in Mongolia and Ujimqin sheep breeds 期刊论文
THERIOGENOLOGY;, 2023, 卷号: 198, 页码: 1-11
作者:  Wang, Yilin;  Chi, Zhijiao;  Jia, Shunan;  Zhao, Suwen;  Cao, Guifang
Adobe PDF(3070Kb)  |  收藏  |  浏览/下载：371/2  |  提交时间：2023/03/24
Point mutations of homologs as an adaptive solution to the gene loss 期刊论文
JOURNAL OF GENETICS AND GENOMES, 2023, 卷号: 50, 期号: 7
作者:  Ma, Guosheng;  Zhao, Xiaojing;  Shentu, Xinyi;  Zhang, Liye
Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：319/3  |  提交时间：2023/04/14
Direct evidence of CRISPR-Cas9-mediated mitochondrial genome editing 期刊论文
INNOVATION, 2022, 卷号: 3, 期号: 6
作者:  Bi, Rui;  Li, Yu;  Xu, Min;  Zheng, Quanzhen;  Zhang, Deng-Feng
Adobe PDF(7305Kb)  |  收藏  |  浏览/下载：272/0  |  提交时间：2023/04/28
Design, synthesis and biological evaluation of novel osimertinib derivatives as reversible EGFR kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238
作者:  Ding, Shi;  Gao, Ziye;  Hu, Ziqiang;  Qi, Rui;  Zheng, Xiangshan
Adobe PDF(8843Kb)  |  收藏  |  浏览/下载：352/0  |  提交时间：2022/08/15
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