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Histone Modifications in NAFLD: Mechanisms and Potential Therapy 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 19
作者:  Shi, Yulei;  Qi, Wei
Adobe PDF(1344Kb)  |  收藏  |  浏览/下载：619/104  |  提交时间：2023/10/31
EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 4
作者:  Chu, Liping;  Tan, Dongxia;  Zhu, Meimei;  Qu, Yuxiu;  Ma, Xin
Adobe PDF(3768Kb)  |  收藏  |  浏览/下载：601/1  |  提交时间：2023/04/07
TMELand: An end-to-end Pipeline for Quantification and Visualization of Waddingtons Epigenetic Landscape based on Gene Regulatory Network 期刊论文
IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2023, 卷号: PP, 期号: 99, 页码: 1-9
作者:  Lin Zhu;  Xin Kang;  Chunhe Li;  Jie Zheng
Adobe PDF(4456Kb)  |  收藏  |  浏览/下载：277/0  |  提交时间：2023/07/14
Chromatin Methylation Abnormalities in Autosomal Dominant Polycystic Kidney Disease 期刊论文
FRONTIERS IN MEDICINE, 2022, 卷号: 9
作者:  Xu, Jing;  Xue, Cheng;  Wang, Xiaodong;  Zhang, Lei;  Mei, Changlin
Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：811/188  |  提交时间：2022/08/15
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 124
作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu
Adobe PDF(2004Kb)  |  收藏  |  浏览/下载：178/0  |  提交时间：2022/05/05
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
Adobe PDF(5109Kb)  |  收藏  |  浏览/下载：381/1  |  提交时间：2021/05/14
The Potential to Fight Obesity with Adipogenesis Modulating Compounds 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 4
作者:  Zhao, Jiaqi;  Zhou, Ailin;  Qi, Wei
Adobe PDF(3281Kb)  |  收藏  |  浏览/下载：824/237  |  提交时间：2022/04/12
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52
作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：329/0  |  提交时间：2022/04/12
Cancer metabolism and tumor microenvironment: fostering each other? 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021
作者:  Yuan, Yiyuan;  Li, Huimin;  Pu, Wang;  Chen, Leilei;  Guo, Dong
Adobe PDF(3311Kb)  |  收藏  |  浏览/下载：267/1  |  提交时间：2021/12/10
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:  Lu, Wenchao;  Xiong, Huan;  Chen, Yu
Adobe PDF(5322Kb)  |  收藏  |  浏览/下载：507/0  |  提交时间：2018/12/10
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