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Excision of HIV-1 Provirus in Human Primary Cells with Nanocapsuled TALEN Proteins
期刊论文
ACS APPLIED BIO MATERIALS, 2025, 卷号: 8, 期号: 2, 页码: 1227-1239
作者:
Zhao, Ming
;
Wen, Jing
;
Chen, Irvin S. Y.
;
Liu, Jia
;
Lu, Yunfeng
Adobe PDF(6801Kb)
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浏览/下载:52/2
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提交时间:2025/02/28
T-cells
Transcription
Gene editing
Human immunodeficiency virus
Human immunodeficiency virus provirus elimination
Primary T cell
Protein delivery
Response elements
Trans-activation response
Trans-activation response element
Transcription activator-like effector nuclease nanoparticle
Transcription activators
Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
;
He, Yayi
;
Zhu, Weikang
Adobe PDF(7984Kb)
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浏览/下载:175/3
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提交时间:2024/12/30
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
Rab2B promotes chaperonin-mediated actin folding and prevents developmental transcription reprogramming and quiescence in trypanosomes
预印本
2024
作者:
Li, Feng-Jun
;
Dong, Xiaoduo
;
Huang, Yameng
;
Hu, Donghui
;
Chae, Eunyoung
Adobe PDF(15673Kb)
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浏览/下载:137/11
|
提交时间:2025/01/13
Rab2B
autophagy
differentiation
chaperonin (CCT/TRiC)
actin
folding
RNA polymerase II
transcription
Trypanosoma brucei
life cycle
Functional characterization of two reductase KshBs in Mycobacterium fortuitum and their applications to C9 non-hydroxylated steroid production
期刊论文
PROCESS BIOCHEMISTRY, 2024, 卷号: 145, 页码: 22-31
作者:
He, Beiru
;
Liu, Xiangcen
;
Zhai, Xinghui
Adobe PDF(3741Kb)
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浏览/下载:305/7
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提交时间:2024/07/05
Alcohols
Enzyme activity
Hydroxylation
Metabolism
Strain
Transcription
17-dione (4-androstene-3,17-dione)
3-ketosteroid-9α-hydroxylase
4-androstene-3
Functional characterization
Hydroxylases
Kshb
Monooxygenases
Mycobacteria
Phytosterol
Two-component
PPARγ and C/EBPα enable adipocyte differentiation upon inhibition of histone methyltransferase PRC2 in malignant tumors
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 10
作者:
Zhao, Jiaqi
Adobe PDF(8402Kb)
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浏览/下载:301/7
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提交时间:2024/11/08
Cell culture
Transcription
Adipocyte differentiation
C/EBPα sarcoma
Histone methyltransferases
Malignant tumors
Mesenchymal stem cell
Peroxisome proliferator-activated receptor
Polycomb
Polycomb repressive complex 2 inhibitor
PPARγ
Terminal differentiation
DNFE: Directed-network flow entropy for detecting the tipping points during biological processes
预印本
2024
作者:
Peng, Xueqing
;
Li, Peiluan
;
Luonan, Chen
收藏
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浏览/下载:198/0
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提交时间:2024/10/08
directed network
scRNA-seq
critical states
dynamic network biomarker
transcription factor
The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 5
作者:
Wu, Mengying
;
Hu, Liqiao
;
He, Lingli
Adobe PDF(2194Kb)
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浏览/下载:272/3
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提交时间:2024/05/11
Acylation
Cell signaling
Transcription
Transcription factors
Tumors
Coactivators
Crucial functions
Direct interactions
Direct links
Hippo pathway
Palmitoylation
Protein-protein interactions
Signalling pathways
TEAD4
Tumour suppressor
GTF2H4 regulates partial EndMT via NF-κB activation through NCOA3 phosphorylation in ischemic diseases
期刊论文
INNOVATION, 2024, 卷号: 5, 期号: 2
作者:
Fang, Zheyan
;
Zhao, Gang
;
Zhao, Shuang
;
Yu, Xueting
;
Feng, Runyang
Adobe PDF(11456Kb)
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浏览/下载:410/2
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提交时间:2024/03/08
Amino acids
Chemical activation
Endothelial cells
Molecular biology
Transcription
Angiogenesis
Coactivators
Complementation
Endothelial-cells
Excision repair
Ischemic conditions
Neo-vascularization
Proteomics
Site directed mutagenesis
Target proteins
Epigenetic regulation in adult neural stem cells
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2024, 卷号: 12
作者:
Shi,Jiajia
;
Wang,zilin
;
Wang,zhijun
;
Shao,guofeng
;
Li,xiajun
Adobe PDF(1308Kb)
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浏览/下载:365/10
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提交时间:2024/03/18
neural stem cell (NSC)
epigenetic
transcription
adult brain
DNA methylation
CRISPR-dCas13-tracing reveals transcriptional memory and limited mRNA export in developing zebrafish embryos
期刊论文
GENOME BIOLOGY;, 2023, 卷号: 24, 期号: 1
作者:
Huang, Youkui
;
Gao, Bao-Qing
;
Meng, Quan
;
Yang, Liang-Zhong
;
Ma, Xu-Kai
Adobe PDF(6885Kb)
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收藏
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浏览/下载:1016/262
|
提交时间:2023/03/24
De novo transcription
Developmental embryos
Modified gRNAs
mRNP export
Post-mitotic
Zygotic microinjection
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