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A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
Adobe PDF(18107Kb)
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浏览/下载:76/2
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提交时间:2025/02/12
Ablation
Biological organs
Chemotherapy
Gene expression
Gene therapy
Lung cancer
Mammals
Nanoparticles
Oligonucleotides
Transplantation (surgical)
Docetaxel
Endosomal escapes
Nano-devices
PH-responsive
Prodrug nanoparticle
Prodrugs
Receptor 1 small interference RNA
Receptor-1
Small interference RNA
Triple-negative breast cancers
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors
期刊论文
ARCHIV DER PHARMAZIE, 2024
作者:
An, Yuxiang
;
Peng, Xia
;
Wang, Tianchen
;
Liu, Kaiyuan
;
Feng, Dazhi
Adobe PDF(3528Kb)
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浏览/下载:185/2
|
提交时间:2024/12/04
inhibitor
pharmacokinetic study
pyridazin-4-one
receptor-interacting protein kinase 1
selectivity
Evaluation of a Positron Emission Tomography Tracer Targeting Colony-Stimulating Factor 1 Receptor for Detecting Pulmonary Inflammation
期刊论文
MOLECULAR PHARMACEUTICS, 2024
作者:
Hui, Wenxue
;
Pu, Suyun
;
Gao, Xinyan
;
Wang, Yunze
;
Zha, Xiaochuan
Adobe PDF(9669Kb)
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浏览/下载:208/5
|
提交时间:2024/07/15
colony-stimulating factor 1 receptor
positronemissiontomography
radiotracer
PET imaging
pulmonaryinflammation
Resting State Brain Networks under Inverse Agonist versus Complete Knockout of the Cannabinoid Receptor 1
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 8
作者:
Li, Hui
;
Ye, Qiong
;
Wang, Da
;
Shi, Bowen
;
Xu, Wenjing
Adobe PDF(7070Kb)
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浏览/下载:275/1
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提交时间:2024/05/14
cannabinoid receptor 1
gene knockout
rimonabant
magnetic resonance imaging
network activity
directional uniformity
BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma
期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 12
作者:
Liu, Dongdong
;
Li, Zhen
;
Tan, Dongxia
;
An, Yang
;
Chu, Liping
Adobe PDF(14405Kb)
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浏览/下载:521/6
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提交时间:2024/02/02
Bone
Cell signaling
Cytology
Oncology
Proteins
Activin A receptor type 1
B cells
B-Cell Lymphoma
Bone morphogenetic proteins
Cancer therapeutics
Catalytic subunits
Germinal centers
Histone methyltransferases
Polycomb
Polycomb repressive complex 2 inhibitor
Fenofibrate Recognition and Gq Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1
期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 14
作者:
Wang, Tianxin
;
Tang, Wenqin
;
Zhao, Ziyi
;
Zhao, Ran
;
Lv, Zhenyu
Adobe PDF(4903Kb)
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浏览/下载:220/13
|
提交时间:2024/09/21
Cryo-electron microscopy
Cannabinoid receptors
Coupling mechanism
Fenofibrate
Electron microscopes
Electron microscopy
Medical imaging
G protein
Gq coupling
Human cannabinoid receptor 1
Human cannabinoid receptors
Ligand recognition
Receptor-1
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules
期刊论文
AUTOPHAGY, 2023, 卷号: 19, 期号: 7, 页码: 1934-1951
作者:
Yang, Cuiwei
;
Wang, Zhangshun
;
Kang, Yingjin
;
Yi, Qianqian
;
Wang, Tong
Adobe PDF(5826Kb)
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收藏
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浏览/下载:656/1
|
提交时间:2023/02/24
Autophagy receptor
CALCOCO2
G3BP1
SQSTM1
stress granule
TRIM21
ubiquitination
Affinity selection of double-click triazole libraries for rapid discovery of allosteric modulators for GLP-1 receptor
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 11, 页码: e2220767120
作者:
Xin, Ye
;
Liu, Shuo
;
Liu, Yan
;
Qian, Zhen
;
Liu, Hongyue
Adobe PDF(4481Kb)
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浏览/下载:636/4
|
提交时间:2023/03/13
click chemistry
affinity selection mass spectrometry
GLP-1 receptor
allosteric modulators
Fluoxetine reverses hyperactivity of anterior cingulate cortex and attenuates chronic stress-induced hyperalgesia
期刊论文
NEUROPHARMACOLOGY, 2022, 卷号: 220
作者:
Qi, Meiru
;
Li, Chenglin
;
Li, Jie
;
Zhu, Xiao na
;
Lu, Chen
Adobe PDF(5266Kb)
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收藏
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浏览/下载:412/1
|
提交时间:2022/10/08
5-HT1A receptor
Anterior cingulate cortex
Chronic stress
Fluoxetine
Hyperalgesia
A phosphate starvation response-regulated receptor-like kinase, OsADK1, is required for mycorrhizal symbiosis and phosphate starvation responses
期刊论文
NEW PHYTOLOGIST, 2022, 卷号: 236, 期号: 6, 页码: 2282-2293
作者:
Shi, Jincai
;
Zhao, Boyu
;
Jin, Rui
;
Hou, Ling
;
Zhang, Xiaowei
Adobe PDF(3179Kb)
|
收藏
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浏览/下载:250/0
|
提交时间:2022/11/22
arbuscular mycorrhizal symbiosis
arbuscule development
DAP-seq
OsADK1
OsPHR1
2
3
receptor-like kinase
rice (Oryza sativa)
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