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"Living Detergents": an in Situ Detergent Tailoring Strategy for Efficient Membrane Protein Stabilization and Analysis
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2025, 卷号: 31, 期号: 28
作者:
Dai, Yili
;
Yang, Meifang
;
Luo, Weiling
;
Qiu, Yanli
;
Zhou, Fang
Adobe PDF(1188Kb)
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浏览/下载:31/2
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提交时间:2025/05/06
bioorthogonal reaction
living detergent
membrane proteins
micelle
Introduction
Enzyme Surface Residues Direct Encapsulation into Metal–Organic Frameworks for Performance Regulation
期刊论文
ANGEWANDTE CHEMIE - INTERNATIONAL EDITION, 2025, 卷号: 64, 期号: 20
作者:
Wu, Mengyao
;
Du, Yuexin
;
Xu, Hui
;
Zhang, Xiehaoran
;
Ma, Jialong
Adobe PDF(11670Kb)
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浏览/下载:84/4
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提交时间:2025/03/14
Crystalline materials - Enzyme activity - Enzyme immobilization - Metal-Organic Frameworks
Cytochrome c - Enzyme catalysis - Immobilisation - Metalorganic frameworks (MOFs) - Modified proteins - Performance - Structure-activity relationships - Surface residues - Surface-modification - Template synthesis
metal-organic frameworks
enzyme catalysis
template synthesis
immobilization
structure-activity relationships
Aberrant outputs of glutamatergic neurons in deep cerebellar nuclei mediate dystonic movements
期刊论文
SCIENCE ADVANCES, 2025, 卷号: 11, 期号: 19
作者:
Wu, Xue-Mei
;
Lu, Bin
;
He, Jun-Yan
;
Zhang, Yu-Xian
;
Wu, Zhi-Ying
Adobe PDF(7313Kb)
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收藏
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浏览/下载:13/1
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提交时间:2025/05/26
Rats
Animal model
GABAergic
Kainic acid
Mice models
Mutant mice
Neuronal populations
Optogenetics
Selective ablations
Trans-membrane proteins
Transmembrane proteins
Combined treatment targeting Ca2+store mediated Ca2+release and store-operated calcium entry reduces secondary axonal degeneration and improves functional outcome after SCI
期刊论文
EXPERIMENTAL NEUROLOGY, 2025, 卷号: 386
作者:
Jones, Emma
;
Ames, Spencer O.
;
Brooks, Jesse
;
Morehouse, Johnny
;
Hill, Norah
Adobe PDF(5086Kb)
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浏览/下载:112/4
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提交时间:2025/03/03
Spinal cord injury
Store-operated calcium entry (SOCE)
Axoplasmic reticulum
Stromal interaction molecule proteins (STIM)
Orai
IP3R
Axonal degeneration
Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer disease phenotypes in mouse models
期刊论文
NATURE BIOTECHNOLOGY, 2025
作者:
Feng, Xin
;
Jiang, Bo-Wen
;
Zhai, Si-Nan
;
Liu, Chu-Xiao
;
Wu, Hao
收藏
|
浏览/下载:56/0
|
提交时间:2025/04/11
Disease control
Neurodegenerative diseases
Neurons
Adeno-associated virus
Alzheimers disease
Disease phenotypes
Mice models
Neuroinflammation
Proinflammatory molecules
Protein kinase
RNA aptamer
Small-molecule inhibitors
Target proteins
Peptide-Scaffolded Detergents for Membrane Protein Studies
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2025, 卷号: 31, 期号: 16
作者:
Yang, Meifang
;
Dai, Yili
;
Zhou, Fang
;
Zhou, Xin
;
Qiu, Yanli
Adobe PDF(3689Kb)
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收藏
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浏览/下载:86/3
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提交时间:2025/03/10
Peptide-scaffolded detergents
Membrane proteins
Micelle
Click reaction
Exploring Enzyme Encapsulation Efficiency in MOFs Using Eco-Friendly Approaches
期刊论文
CHEMSUSCHEM, 2025, 卷号: 18, 期号: 3
作者:
Hieu Vo, Trung
;
Lin, Shang-Wei
;
Lin, Miao-Chun
;
Kuan, Pu-Yun
;
Chen, Jing-Hui
Adobe PDF(3315Kb)
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收藏
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浏览/下载:216/2
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提交时间:2024/11/22
Controlled drug delivery
Crystalline materials
Encapsulation
Metal-Organic Frameworks
Eco-friendly
Encapsulation efficiency
Encapsulation of proteins
Enzyme encapsulation
Enzyme loading
Iso-electric points
Mechano-chemistry
Metalorganic frameworks (MOFs)
Point value
Water based
Therapeutic application of circular RNA aptamers in a mouse model of psoriasis
期刊论文
NATURE BIOTECHNOLOGY, 2025, 卷号: 43, 期号: 2
作者:
Guo, Si-Kun
;
Liu, Chu-Xiao
;
Xu, Yi-Feng
;
Wang, Xiao
;
Nan, Fang
Adobe PDF(16045Kb)
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收藏
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浏览/下载:382/0
|
提交时间:2024/05/11
Biosynthesis
Dermatology
Activated proteins
Down-stream
Immunogenicity
Mice models
Protein kinase
RNA aptamer
Synthesised
Therapeutic Application
Therapeutic modality
Therapeutic potentials
The integration of artificial intelligence and protein science: the protein structure prediction and protein design revolution behind the 2024 Nobel Prize in Chemistry
期刊论文
CHINESE SCIENCE BULLETIN, 2025, 卷号: 70, 期号: 10, 页码: 1421-1427
作者:
Liu, Shenhui
;
Liu, Zhi-Jie
Adobe PDF(781Kb)
|
收藏
|
浏览/下载:10/1
|
提交时间:2025/05/30
Bioinformatics
Biomineralization
Elastin
Peptides
Vaccines
Alphafold2
Amino acid sequence
Artificial intelligence
Intelligence science
Nobel prize in chemistry
Nobel prizes
Protein design
Protein science
Protein structure prediction
Proteins structures
Exploring Protein Conformational Changes Using a Large-Scale Biophysical Sampling Augmented Deep Learning Strategy
期刊论文
ADVANCED SCIENCE, 2024, 卷号: 11, 期号: 44
作者:
Yao Hu
;
Hao Yang
;
Mingwei Li
;
Zhicheng Zhong
;
Yongqi Zhou
Adobe PDF(6212Kb)
|
收藏
|
浏览/下载:503/10
|
提交时间:2024/09/11
conformational changes
deep learning
proteins
transition pathway
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