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An Engineered Intravitreal Injection Retinal-Pigment-Epithelium-Tropic Adeno-Associated Virus Vector Expressing a Bispecific Antibody Binding VEGF-A and ANG-2 Rescues Neovascular Age-Related Macular Degeneration in Animal Models and Patients 期刊论文
RESEARCH, 2025, 卷号: 8
作者:  Cai, Yuan;  Gu, Yonghao;  Zhang, Jie;  Zhu, Ying;  Ma, Zhen
Adobe PDF(9093Kb)  |  收藏  |  浏览/下载：18/3  |  提交时间：2025/06/09
Deciphering enhancers of hearing loss genes for efficient and targeted gene therapy of hereditary deafness 期刊论文
NEURON, 2025
作者:  Simeng Zhao;  Qiuxiang Yang;  Zehua Yu;  Cenfeng Chu;  Shengqi Dai
Adobe PDF(9318Kb)  |  收藏  |  浏览/下载：60/10  |  提交时间：2025/05/12
Lung-Specific mRNA Delivery by Ionizable Lipids with Defined Structure-Function Relationship and Unique Protein Corona Feature 期刊论文
ADVANCED SCIENCE, 2025, 卷号: 12, 期号: 14
作者:  He, Xiaoyan;  Wang, Runyuan;  Cao, Yan;  Ding, Yan;  Chang, Yan
Adobe PDF(14333Kb)  |  收藏  |  浏览/下载：106/12  |  提交时间：2025/03/03
Targeted Delivery of mRNA with Polymer-Lipid Nanoparticles for In Vivo Base Editing 期刊论文
ACS NANO, 2025, 卷号: 19, 期号: 8, 页码: 7835-7850
作者:  Chen, Qimingxing;  Chang, Yan;  He, Xiaoyan;  Ding, Yan;  Wang, Runyuan
Adobe PDF(12364Kb)  |  收藏  |  浏览/下载：155/27  |  提交时间：2025/02/28
A novel AAV Vector for gene therapy of RPE-related retinal degenerative diseases via intravitreal delivery 期刊论文
MOLECULAR NEURODEGENERATION, 2024, 卷号: 19, 期号: 1
作者:  Gong, Yajun;  Huang, Xianyu;  Tu, Tianxiang;  Chu, Cenfeng;  Xian, Chunrui
Adobe PDF(1205Kb)  |  收藏  |  浏览/下载：289/8  |  提交时间：2024/12/17
Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases 期刊论文
CELL STEM CELL, 2024, 卷号: 31, 期号: 8
作者:  Zhang, Kun;  Wan, Ping;  Wang, Liren;  Wang, Zhen;  Tan, Fangzhi
Adobe PDF(9769Kb)  |  收藏  |  浏览/下载：388/10  |  提交时间：2024/08/26
Critical role of TPRN rings in the stereocilia for hearing 期刊论文
MOLECULAR THERAPY, 2024, 卷号: 32, 期号: 1, 页码: 204-217
作者:  Qi, Jieyu;  Tan, Fangzhi;  Zhang, Liyan;  Zhou, Yinyi;  Zhang, Ziyu
Adobe PDF(6596Kb)  |  收藏  |  浏览/下载：464/5  |  提交时间：2024/03/04
具有变体衣壳蛋白的腺相关病毒及其用途 专利
申请号:EP19912419，申请日期: 2023-10-18，类型:检索报告，状态:撤回
发明人:  Tan Fangzhi;  Zhong Guisheng;  Chu Cenfeng;  Qi Jieyu
Unknown(3721Kb)  |  收藏  |  浏览/下载：456/0  |  提交时间：2023/10/20
A Screening Strategy of Synthetic AAVs for Cell Type-Specific Targeting and Precise Gene Therapy 会议论文
MOLECULAR THERAPY
作者:  Chu, Cenfeng;  Zhang, Huifang;  Jia, Guodong;  Zhong, Guisheng
收藏  |  浏览/下载：324/0  |  提交时间：2023/10/31
Developing Novel AAV Capsids for Ophthalmic Gene Therapy 会议论文
MOLECULAR THERAPY
作者:  Chu, Cenfeng;  Zhang, Huifang;  Jia, Guodong;  Zhong, Guisheng
收藏  |  浏览/下载：336/0  |  提交时间：2023/10/31
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