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Detection of 2,2 '-Azobis(2-amidinopropane) Dihydrochloride in Polyvinylpyrrolidone by Capillary Electrophoresis with Field-Amplified Sample Injection | |
2019-10 | |
发表期刊 | CHROMATOGRAPHIA (IF:1.2[JCR-2023],1.7[5-Year]) |
ISSN | 0009-5893 |
卷号 | 82期号:10页码:1579-1583 |
发表状态 | 已发表 |
DOI | 10.1007/s10337-019-03765-2 |
摘要 | A sensitive method was developed for detecting 2,2 '-azobis(2-amidinopropane) dihydrochloride in polyvinylpyrrolidone by capillary electrophoresis with indirect UV detection. The detection sensitivity was improved significantly using the field-amplified sample injection technique. The background electrolyte was composed of 25 mM imidazole-HCl solution (pH 4.0), in which imidazole acted as the cation probe for the indirect detection at UV 214 nm. Effects of the experimental parameters including pH, the concentration of imidazole as well as the sample injection time on sample preconcentration were investigated and optimized. Under the optimized conditions, baseline separation of 2,2 '-azobis(2-amidinopropane) ion with other ions in the polyvinylpyrrolidone samples was achieved within 8 min. The RSD% for the repeatability of the migration time and the peak area were determined as 0.95% and 3.47%, respectively. The limit of detection (LOD, S/N = 3) and the limit of quantitation (LOQ, S/N = 10) were determined as 1.11 x 10(-5) M and 2.77 x 10(-5) M, respectively. The measured recovery at three concentration levels was in the range of 101-104%. This method was successfully applied to detect 2,2 '-azobis(2-amidinopropane) in the commercial polyvinylpyrrolidone samples. |
关键词 | Capillary electrophoresis Field-amplified sample injection Polyvinylpyrrolidone 2 2 '-Azobis(2-amidinopropane) dihydrochloride |
收录类别 | SCI ; SCIE |
语种 | 英语 |
资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDB20020200] |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
WOS类目 | Biochemical Research Methods ; Chemistry, Analytical |
WOS记录号 | WOS:000485313700014 |
出版者 | SPRINGER HEIDELBERG |
WOS关键词 | SENSITIVITY ENHANCEMENT ; STACKING ; PRECONCENTRATION ; ANIONS |
原始文献类型 | Article |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/80227 |
专题 | 物质科学与技术学院_硕士生 物质科学与技术学院_特聘教授组_康经武组 |
通讯作者 | Kang, Jingwu |
作者单位 | 1.ShanghaiTech Univ, Sch Phys Sci & Technol, Haike Rd 100, Shanghai 200120, Peoples R China 2.Chinese Acad Sci, State Key Lab Bioorgan & Nat Prod Chem, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19, Beijing 100049, Peoples R China |
第一作者单位 | 物质科学与技术学院 |
通讯作者单位 | 物质科学与技术学院 |
第一作者的第一单位 | 物质科学与技术学院 |
推荐引用方式 GB/T 7714 | Lou, Chunli,Zheng, Mengmeng,Xu, Yao,et al. Detection of 2,2 '-Azobis(2-amidinopropane) Dihydrochloride in Polyvinylpyrrolidone by Capillary Electrophoresis with Field-Amplified Sample Injection[J]. CHROMATOGRAPHIA,2019,82(10):1579-1583. |
APA | Lou, Chunli,Zheng, Mengmeng,Xu, Yao,Shen, Yuting,&Kang, Jingwu.(2019).Detection of 2,2 '-Azobis(2-amidinopropane) Dihydrochloride in Polyvinylpyrrolidone by Capillary Electrophoresis with Field-Amplified Sample Injection.CHROMATOGRAPHIA,82(10),1579-1583. |
MLA | Lou, Chunli,et al."Detection of 2,2 '-Azobis(2-amidinopropane) Dihydrochloride in Polyvinylpyrrolidone by Capillary Electrophoresis with Field-Amplified Sample Injection".CHROMATOGRAPHIA 82.10(2019):1579-1583. |
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