High-Frequency 64-Element Ring-Annular Array Transducer: Development and Preclinical Validation for Intravascular Ultrasound Imaging

doi:10.3390/bios15030169

	High-Frequency 64-Element Ring-Annular Array Transducer: Development and Preclinical Validation for Intravascular Ultrasound Imaging
	Liu, Xi; Li, Yuanlong; Qin, Haiguo; Peng, Chang
	2025-03-05
发表期刊	BIOSENSORS-BASEL (IF:4.9[JCR-2023],5.2[5-Year])
EISSN	2079-6374
卷号	15 期号:3
发表状态	已发表
DOI	10.3390/bios15030169
摘要	Intravascular ultrasound (IVUS) imaging has become an essential method for diagnosing coronary artery disease. However, traditional mechanically rotational IVUS catheters encounter issues such as mechanical wear and imaging distortions in curved vessels. The ring-annular IVUS array has gained attention because it offers superior imaging performance without the need for mechanical rotational parts, thereby avoiding rotational imaging distortion. An optimized mechanical micromachining process employing precision dicing technology is proposed in this study, with the objective of achieving higher operating frequencies and minimized outer diameters for a 64-element ring-annular array. This method broadens the range of fabrication options and improves the imaging sensitivity of ring-annular IVUS arrays, as well as eliminating imaging distortion in rotational IVUS catheters, particularly in curved vessels. The probe has a 7.5 Fr (2.5 mm) outer diameter, with key fabrication steps including precision dicing, flexible circuit integration, and Parylene C encapsulation. The ring-annular array has a center frequency of 21.51 MHz with 67.87% bandwidth, with a 56 mu m axial resolution and a 276 mu m lateral resolution. The imaging performance is further validated by in vitro phantom imaging and ex vivo imaging.
关键词	intravascular ultrasound ring-annular array ultrasound imaging ultrasound transducer
URL	查看原文
收录类别	SCI ; EI
语种	英语
资助项目	National Natural Science Foundation of China[12204307] ; null[22YF1428900]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Nanoscience & Nanotechnology ; Instruments & Instrumentation
WOS记录号	WOS:001452968000001
出版者	MDPI
EI入藏号	20251318142122
EI主题词	Catheters
EI分类号	101.2 Biomedical Equipment ; 715 Electronic Equipment, General Purpose and Industrial ; 746 Imaging Techniques ; 753.2 Ultrasonic Devices ; 753.3 Ultrasonic Applications
原始文献类型	Journal article (JA)
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/493559
专题	生物医学工程学院信息科学与技术学院_硕士生生物医学工程学院_PI研究组_彭畅组生物医学工程学院_硕士生生物医学工程学院_硕士生
通讯作者	Peng, Chang
作者单位	ShanghaiTech Univ, Sch Biomed Engn, Shanghai 201210, Peoples R China
第一作者单位	生物医学工程学院
通讯作者单位	生物医学工程学院
第一作者的第一单位	生物医学工程学院
推荐引用方式 GB/T 7714	Liu, Xi,Li, Yuanlong,Qin, Haiguo,et al. High-Frequency 64-Element Ring-Annular Array Transducer: Development and Preclinical Validation for Intravascular Ultrasound Imaging[J]. BIOSENSORS-BASEL,2025,15(3).
APA	Liu, Xi,Li, Yuanlong,Qin, Haiguo,&Peng, Chang.(2025).High-Frequency 64-Element Ring-Annular Array Transducer: Development and Preclinical Validation for Intravascular Ultrasound Imaging.BIOSENSORS-BASEL,15(3).
MLA	Liu, Xi,et al."High-Frequency 64-Element Ring-Annular Array Transducer: Development and Preclinical Validation for Intravascular Ultrasound Imaging".BIOSENSORS-BASEL 15.3(2025).