ShanghaiTech University Knowledge Management System
A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics | |
Gao, Zehang1,2,3; Peng, Huo1,3; Zhu, Minjie1,4; Wu, Lei1; Jia, Chunping1; Zhou, Hongbo1; Zhao, Jianlong1 | |
2019-05 | |
发表期刊 | MICROMACHINES |
ISSN | 2072-666X |
卷号 | 10期号:5 |
发表状态 | 已发表 |
DOI | 10.3390/mi10050291 |
摘要 | In droplet-based microfluidics, visualizing and modulating of droplets is often prerequisite. In this paper, we report a facile strategy for visualizing and modulating high-throughput droplets in microfluidics. In the strategy, by modulating the sampling frequency of a flash light with the droplet frequency, we are able to map a real high frequency signal to a low frequency signal, which facilitates visualizing and feedback controlling. Meanwhile, because of not needing synchronization signals, the strategy can be directly implemented on any droplet-based microfluidic chips. The only cost of the strategy is an additional signal generator. Moreover, the strategy can catch droplets with frequency up to several kilohertz, which covers the range of most high-throughput droplet-based microfluidics. In this paper, the principle, setup and procedure were introduced. Finally, as a demonstration, the strategy was also implemented in a miniaturized picoinjector in order to monitor and control the injection dosage to droplets. We expect that this facile strategy supplies a low-cost yet effective imaging system that can be easily implemented in miniaturized microfluidic systems or general laboratories. |
关键词 | microfluidics droplets high-throughput modulate |
收录类别 | SCI ; SCIE ; EI |
语种 | 英语 |
资助项目 | Science and technology support plan of the Shanghai Science and Technology Committee[17441904300] |
WOS研究方向 | Science & Technology - Other Topics ; Instruments & Instrumentation |
WOS类目 | Nanoscience & Nanotechnology ; Instruments & Instrumentation |
WOS记录号 | WOS:000470966700014 |
出版者 | MDPI |
EI主题词 | Drops ; Fluidic devices |
WOS关键词 | THROUGHPUT ; GENERATION ; DYNAMICS ; PLATFORM ; BREAKUP |
原始文献类型 | Article |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/49003 |
专题 | 信息科学与技术学院_博士生 |
通讯作者 | Zhou, Hongbo; Zhao, Jianlong |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, State Key Lab Transducer Technol, Shanghai 200050, Peoples R China 2.ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai 201210, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Shanghai Univ, Dept Chem, Coll Sci, Shanghai 200444, Peoples R China |
第一作者单位 | 信息科学与技术学院 |
推荐引用方式 GB/T 7714 | Gao, Zehang,Peng, Huo,Zhu, Minjie,et al. A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics[J]. MICROMACHINES,2019,10(5). |
APA | Gao, Zehang.,Peng, Huo.,Zhu, Minjie.,Wu, Lei.,Jia, Chunping.,...&Zhao, Jianlong.(2019).A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics.MICROMACHINES,10(5). |
MLA | Gao, Zehang,et al."A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics".MICROMACHINES 10.5(2019). |
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