A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics
Gao, Zehang1,2,3; Peng, Huo1,3; Zhu, Minjie1,4; Wu, Lei1; Jia, Chunping1; Zhou, Hongbo1; Zhao, Jianlong1
2019-05
发表期刊MICROMACHINES
ISSN2072-666X
卷号10期号:5
发表状态已发表
DOI10.3390/mi10050291
摘要In droplet-based microfluidics, visualizing and modulating of droplets is often prerequisite. In this paper, we report a facile strategy for visualizing and modulating high-throughput droplets in microfluidics. In the strategy, by modulating the sampling frequency of a flash light with the droplet frequency, we are able to map a real high frequency signal to a low frequency signal, which facilitates visualizing and feedback controlling. Meanwhile, because of not needing synchronization signals, the strategy can be directly implemented on any droplet-based microfluidic chips. The only cost of the strategy is an additional signal generator. Moreover, the strategy can catch droplets with frequency up to several kilohertz, which covers the range of most high-throughput droplet-based microfluidics. In this paper, the principle, setup and procedure were introduced. Finally, as a demonstration, the strategy was also implemented in a miniaturized picoinjector in order to monitor and control the injection dosage to droplets. We expect that this facile strategy supplies a low-cost yet effective imaging system that can be easily implemented in miniaturized microfluidic systems or general laboratories.
关键词microfluidics droplets high-throughput modulate
收录类别SCI ; SCIE ; EI
语种英语
资助项目Science and technology support plan of the Shanghai Science and Technology Committee[17441904300]
WOS研究方向Science & Technology - Other Topics ; Instruments & Instrumentation
WOS类目Nanoscience & Nanotechnology ; Instruments & Instrumentation
WOS记录号WOS:000470966700014
出版者MDPI
EI主题词Drops ; Fluidic devices
WOS关键词THROUGHPUT ; GENERATION ; DYNAMICS ; PLATFORM ; BREAKUP
原始文献类型Article
引用统计
文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/49003
专题信息科学与技术学院_博士生
通讯作者Zhou, Hongbo; Zhao, Jianlong
作者单位1.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, State Key Lab Transducer Technol, Shanghai 200050, Peoples R China
2.ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai 201210, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Shanghai Univ, Dept Chem, Coll Sci, Shanghai 200444, Peoples R China
第一作者单位信息科学与技术学院
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GB/T 7714
Gao, Zehang,Peng, Huo,Zhu, Minjie,et al. A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics[J]. MICROMACHINES,2019,10(5).
APA Gao, Zehang.,Peng, Huo.,Zhu, Minjie.,Wu, Lei.,Jia, Chunping.,...&Zhao, Jianlong.(2019).A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics.MICROMACHINES,10(5).
MLA Gao, Zehang,et al."A Facile Strategy for Visualizing and Modulating Droplet-Based Microfluidics".MICROMACHINES 10.5(2019).
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