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3D B1+corrected simultaneous myocardial T1 and T1Ï mapping with subject-specific respiratory motion correction and water-fat separation | |
2025-02 | |
发表期刊 | MAGNETIC RESONANCE IN MEDICINE (IF:3.0[JCR-2023],3.3[5-Year]) |
ISSN | 0740-3194 |
EISSN | 1522-2594 |
卷号 | 93期号:2页码:751-760 |
发表状态 | 已发表 |
DOI | 10.1002/mrm.30317 |
摘要 | PurposeTo develop a 3D free-breathing cardiac multi-parametric mapping framework that is robust to confounders of respiratory motion, fat, and B1+ inhomogeneities and validate it for joint myocardial T1 and T1 rho mapping at 3T. MethodsAn electrocardiogram-triggered sequence with dual-echo Dixon readout was developed, where nine cardiac cycles were repeatedly acquired with inversion recovery and T1 rho preparation pulses for T1 and T1 rho sensitization. A subject-specific respiratory motion model relating the 1D diaphragmatic navigator to the respiration-induced 3D translational motion of the heart was constructed followed by respiratory motion binning and intra-bin 3D translational and inter-bin non-rigid motion correction. Spin history B1+ inhomogeneities were corrected with optimized dual flip angle strategy. After water-fat separation, the water images were matched to the simulated dictionary for T1 and T1 rho quantification. Phantoms and 10 heathy subjects were imaged to validate the proposed technique. ResultsThe proposed technique achieved strong correlation (T1: R-2 = 0.99; T1 rho: R-2 = 0.98) with the reference measurements in phantoms. 3D cardiac T1 and T1 rho maps with spatial resolution of 2 x 2 x 4 mm were obtained with scan time of 5.4 +/- 0.5 min, demonstrating comparable T1 (1236 +/- 59 ms) and T1 rho (50.2 +/- 2.4 ms) measurements to 2D separate breath-hold mapping techniques. The estimated B1+ maps showed spatial variations across the left ventricle with the septal and inferior regions being 10%-25% lower than the anterior and septal regions. ConclusionThe proposed technique achieved efficient 3D joint myocardial T1 and T1 rho mapping at 3T with respiratory motion correction, spin history B1+ correction and water-fat separation. |
关键词 | B1+correction cardiac multi-parametric mapping free-breathing T1 mapping T1 rho mapping |
URL | 查看原文 |
收录类别 | SCI ; EI |
语种 | 英语 |
资助项目 | National Natural Science Foundation of China[82102027] ; Shanghai Science and Technology Commission[23TS1400300] ; Cross-disciplinary Research Fund of Shanghai Ninth People's Hospital, Shanghai JiaoTong university School of Medicine[JYJC202134] |
WOS研究方向 | Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:001329656200001 |
出版者 | WILEY |
EI入藏号 | 20244117171064 |
EI主题词 | Phantoms |
EI分类号 | 101.1 ; 101.2.1 ; 101.3 ; 101.4 ; 103 ; 1106.3.1 ; 203 ; 405.3 Surveying ; 701.2 Magnetism: Basic Concepts and Phenomena |
原始文献类型 | Article in Press |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/436495 |
专题 | 生物医学工程学院 信息科学与技术学院_博士生 生物医学工程学院_PI研究组_齐海坤组 生物医学工程学院_PI研究组_胡鹏组 |
通讯作者 | Qi, Haikun |
作者单位 | 1.ShanghaiTech Univ, Sch Biomed Engn, Shanghai, Peoples R China 2.ShanghaiTech Univ, State Key Lab Adv Med Mat & Devices, Shanghai, Peoples R China 3.Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Shanghai, Peoples R China 4.United Imaging Healthcare, Shanghai, Peoples R China 5.UIH Amer Inc, Houston, TX USA 6.Kings Coll London, Sch Biomed Engn & Imaging Sci, London, England 7.Pontificia Univ Catolica Chile, Sch Engn, Santiago, Chile 8.Millenium Inst Intelligent Healthcare Engn, Santiago, Chile |
第一作者单位 | 生物医学工程学院; 上海科技大学 |
通讯作者单位 | 生物医学工程学院; 上海科技大学 |
第一作者的第一单位 | 生物医学工程学院 |
推荐引用方式 GB/T 7714 | Qi, Haikun,Lv, Zhenfeng,Diao, Jiameng,et al. 3D B1+corrected simultaneous myocardial T1 and T1Ï mapping with subject-specific respiratory motion correction and water-fat separation[J]. MAGNETIC RESONANCE IN MEDICINE,2025,93(2):751-760. |
APA | Qi, Haikun.,Lv, Zhenfeng.,Diao, Jiameng.,Tao, Xiaofeng.,Hu, Junpu.,...&Hu, Peng.(2025).3D B1+corrected simultaneous myocardial T1 and T1Ï mapping with subject-specific respiratory motion correction and water-fat separation.MAGNETIC RESONANCE IN MEDICINE,93(2),751-760. |
MLA | Qi, Haikun,et al."3D B1+corrected simultaneous myocardial T1 and T1Ï mapping with subject-specific respiratory motion correction and water-fat separation".MAGNETIC RESONANCE IN MEDICINE 93.2(2025):751-760. |
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