Site-Selective Pyridine Carbamoylation Enabled by Consecutive Photoinduced Electron Transfer

doi:10.1021/acscatal.4c04032

	Site-Selective Pyridine Carbamoylation Enabled by Consecutive Photoinduced Electron Transfer
	Wang, Zhan-Jie; Chen, Jun-Jie; Huang, Huan-Ming
	2024-10-01
发表期刊	ACS CATALYSIS (IF:11.3[JCR-2023],12.6[5-Year])
ISSN	2155-5435
EISSN	2155-5435
卷号	14 期号:20 页码:15521-15527
发表状态	已发表
DOI	10.1021/acscatal.4c04032
摘要	The development of innovative approaches for synthesizing amide motifs is consistently in high demand. Herein, we successfully employ readily available oxamic acids as carbamoyl radical precursors to couple with pyridinium salts under metal-free conditions, selectively introducing the amide group into pyridine architectures. The key innovation lies in the successful integration of an acridinium-based photocatalyst, which enables the formation of amide bonds through a consecutive photoinduced electron transfer process. This open-shell strategy exhibits remarkable tolerance toward a wide range of functional groups. Furthermore, the applicability of this method has been extended to complex motifs, demonstrating its versatility. Importantly, this approach serves as a complementary strategy to classical amidation synthesis, offering potential advantages such as improved selectivity and expanded synthetic possibilities.
关键词	site selective carbamoylation pyridine consecutive PET radical
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收录类别	SCI ; EI
语种	英语
资助项目	National Natural Science Foundation of China[22201179]
WOS研究方向	Chemistry
WOS类目	Chemistry, Physical
WOS记录号	WOS:001330094500001
出版者	AMER CHEMICAL SOC
EI入藏号	20244217206806
EI主题词	Pyridine
EI分类号	802.2 Chemical Reactions ; 804.1 Organic Compounds
原始文献类型	Article in Press
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/430830
专题	物质科学与技术学院物质科学与技术学院_硕士生物质科学与技术学院_博士生物质科学与技术学院_PI研究组_黄焕明组
通讯作者	Huang, Huan-Ming
作者单位	ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China
第一作者单位	物质科学与技术学院
通讯作者单位	物质科学与技术学院
第一作者的第一单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Wang, Zhan-Jie,Chen, Jun-Jie,Huang, Huan-Ming. Site-Selective Pyridine Carbamoylation Enabled by Consecutive Photoinduced Electron Transfer[J]. ACS CATALYSIS,2024,14(20):15521-15527.
APA	Wang, Zhan-Jie,Chen, Jun-Jie,&Huang, Huan-Ming.(2024).Site-Selective Pyridine Carbamoylation Enabled by Consecutive Photoinduced Electron Transfer.ACS CATALYSIS,14(20),15521-15527.
MLA	Wang, Zhan-Jie,et al."Site-Selective Pyridine Carbamoylation Enabled by Consecutive Photoinduced Electron Transfer".ACS CATALYSIS 14.20(2024):15521-15527.