Silk-Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural Encoding/Decoding

doi:10.1002/advs.201801617

	Silk-Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural Encoding/Decoding
	Shi, Zhifeng 1; Zheng, Faming 2; Zhou, Zhitao 2; Li, Meng 3; Fan, Zhen 1; Ye, Huanpeng 4; Zhang, Shan 2,5; Xiao, Ting 2,6; Chen, Liang 1; Tao, Tiger H.2,5,7,8 ; Sun, Yun-Lu 9; Mao, Ying 1
	2019-05-03
发表期刊	ADVANCED SCIENCE
ISSN	2198-3844
卷号	6 期号:9
发表状态	已发表
DOI	10.1002/advs.201801617
摘要	Flexible electronics can serve as powerful tools for biomedical diagnosis and therapies of neurological disorders, particularly for application cases with brain-machine interfaces (BMIs). Existing conformal soft bioelectrodes are applicable for basic electrocorticogram (ECoG) collecting/monitoring. Nevertheless, as an emerging and promising approach, further multidisciplinary efforts are still demanded for in-depth exploitations with these conformal soft electronics toward their practical neurophysiological applications in both scientific research and real-world clinical operation. Here, clinically-friendly silk-supported/delivered soft bioelectronics are developed, and multiple functions and features valuable for customizable intracranial applications (e.g., biocompatible and spontaneously conformal coupling with cortical surface, spatiotemporal ECoG detecting/monitoring, electro-neurophysiological neural stimulating/decoding, controllable loading/delivery of therapeutic molecules, and parallel optical readouts of operating states) are integrated.
关键词	brain-machine interfaces conformal transient bioelectronics electrocorticogram neural decoding silk
收录类别	SCI ; SCIE ; EI
语种	英语
资助项目	Shanghai Natural Science Fund[16ZR1442500]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science
WOS类目	Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS记录号	WOS:000467524500009
出版者	WILEY
WOS关键词	ELECTRODE ARRAY ; FIBROIN ; POLYGLYCOLIDE ; DEVICES ; FILMS
原始文献类型	Article
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/40887
专题	物质科学与技术学院_特聘教授组_陶虎组
通讯作者	Tao, Tiger H.; Sun, Yun-Lu; Mao, Ying
作者单位	1.Fudan Univ, Huashan Hosp, Dept Neurosurg, Wulumuqi Zhong Rd 12, Shanghai 200040, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, State Key Lab Transducer Technol, Shanghai 200050, Peoples R China 3.Harvard Univ, Rowland Inst, Cambridge, MA 02142 USA 4.Shanghai Jiao Tong Univ, State Key Lab Mech Syst & Vibrat, Shanghai 200240, Peoples R China 5.Univ Chinese Acad Sci, Sch Grad Study, Beijing 100049, Peoples R China 6.Shanghai Normal Univ, Key Lab Resource Chem, Minist Educ, Shanghai 200234, Peoples R China 7.Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Beijing 100049, Peoples R China 8.Shanghai Tech Univ, Sch Phys Sci & Technol, Shanghai 200031, Peoples R China 9.Jilin Univ, Coll Elect Sci & Engn, State Key Lab Integrated Optoelect, 2699 Qianjin St, Changchun 130012, Jilin, Peoples R China
通讯作者单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Shi, Zhifeng,Zheng, Faming,Zhou, Zhitao,et al. Silk-Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural Encoding/Decoding[J]. ADVANCED SCIENCE,2019,6(9).
APA	Shi, Zhifeng.,Zheng, Faming.,Zhou, Zhitao.,Li, Meng.,Fan, Zhen.,...&Mao, Ying.(2019).Silk-Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural Encoding/Decoding.ADVANCED SCIENCE,6(9).
MLA	Shi, Zhifeng,et al."Silk-Enabled Conformal Multifunctional Bioelectronics for Investigation of Spatiotemporal Epileptiform Activities and Multimodal Neural Encoding/Decoding".ADVANCED SCIENCE 6.9(2019).