Simulation study on the production of medical radioisotopes 186gRe by photonuclear reaction

doi:10.1016/j.radphyschem.2024.111599

	Simulation study on the production of medical radioisotopes 186gRe by photonuclear reaction
	Yang, Y.X.1,2,4; Zhao, W.J.1; Cao, X.G.2,4,5; Wang, H.W.2,4,5; Fan, G.T.2,4,5; Liu, L.X.2; Xu, H.H.2; Hu, X.R.4,5; Li, X.X.4,5; Hao, Z.R.2; Jin, S.4,5; Chen, K.J.4,6 ; Ma, Y.G.3,4
	2024-05
发表期刊	RADIATION PHYSICS AND CHEMISTRY (IF:2.8[JCR-2023],2.6[5-Year])
ISSN	0969-806X
EISSN	1879-0895
卷号	218
发表状态	已发表
DOI	10.1016/j.radphyschem.2024.111599
摘要	The conflict between the production capacity and demand for medical radioisotopes has become more prominent. In addition, for some new types of medical radioisotopes, neutron, and proton-induced reactions are not the best way to generate them with high specific activity. The research status of medical radioisotopes is introduced, then the gamma facility and potential new medical radioisotope candidates based on photonuclear reaction are widely surveyed. The production of medical radioisotope 186gRe is simulated based on the Laser Compton Scattering (LCS) gamma source and bremsstrahlung gamma source. It is found that the next generation quasi-monochromatic, high-flux LCS gamma source can produce medical radioisotope 186gRe with less than 0.05% 188Re impurity with around 400 mb cross section. Meanwhile, the bremsstrahlung gamma source can produce around 200 MBq/g specific activity medical radioisotope 186gRe with realistic electron intensity 3.125 mA. This study and simulations show that photonuclear reaction can be regarded as an alternative route for producing medical radioisotopes. © 2024 Elsevier Ltd
关键词	Compton scattering Radioisotopes Bremsstrahlung Gamma source GEANT4 Laser Compton scattering Medical radioisotopes Neutron-induced reactions Photonuclear reaction Production capacity Production demand Simulation studies
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收录类别	EI ; SCI
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDB34030000] ; National Natural Science Foundation["U1832129","11975210"] ; Youth Innovation Promotion Association Chinese Academy of Sciences[2017309] ; National Key Research and Development Program of China[2022YFA1602404] ; Chinese Academy of Sciences President's International Fellowship Initiative[2021VMA0025]
WOS研究方向	Chemistry ; Nuclear Science & Technology ; Physics
WOS类目	Chemistry, Physical ; Nuclear Science & Technology ; Physics, Atomic, Molecular & Chemical
WOS记录号	WOS:001196624300001
出版者	Elsevier Ltd
EI入藏号	20240815608816
EI主题词	Photons
EI分类号	622.1.1 Radioisotopes ; 931.3 Atomic and Molecular Physics ; 932.1 High Energy Physics
原始文献类型	Journal article (JA)
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/349970
专题	物质科学与技术学院物质科学与技术学院_博士生
通讯作者	Cao, X.G.
作者单位	1.School of Physics and Microeletronics, Zhengzhou university, Zhengzhou; 450001, China; 2.Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai; 201210, China; 3.Key Laboratory of Nuclear Physics and Ion-beam Application (MOE), Institute of Modern Physics, Fudan University, Shanghai; 200433, China; 4.Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai; 201800, China; 5.University of Chinese Academy of Sciences, Beijing; 100049, China; 6.School of Physical Science and Technology, ShanghaiTech University, Shanghai; 201210, China
推荐引用方式 GB/T 7714	Yang, Y.X.,Zhao, W.J.,Cao, X.G.,et al. Simulation study on the production of medical radioisotopes 186gRe by photonuclear reaction[J]. RADIATION PHYSICS AND CHEMISTRY,2024,218.
APA	Yang, Y.X..,Zhao, W.J..,Cao, X.G..,Wang, H.W..,Fan, G.T..,...&Ma, Y.G..(2024).Simulation study on the production of medical radioisotopes 186gRe by photonuclear reaction.RADIATION PHYSICS AND CHEMISTRY,218.
MLA	Yang, Y.X.,et al."Simulation study on the production of medical radioisotopes 186gRe by photonuclear reaction".RADIATION PHYSICS AND CHEMISTRY 218(2024).